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  1. Content type: Research article

    Immunization with neural derived peptides (INDP) as well as scar removal—separately—have shown to induce morphological and functional improvement after spinal cord injury (SCI). In the present study, we compar...

    Authors: Roxana Rodríguez-Barrera, Adrián Flores-Romero, Ana María Fernández-Presas, Elisa García-Vences, Raúl Silva-García, Mina Konigsberg, Liliana Blancas-Espinoza, Vinnitsa Buzoianu-Anguiano, Karla Soria-Zavala, Paola Suárez-Meade and Antonio Ibarra

    Citation: BMC Neuroscience 2017 18:7

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  2. Content type: Research article

    It is well-established that organizational effects of sex steroids during early development are fundamental for sex-typical displays of, for example, mating and aggressive behaviors in rodents and other specie...

    Authors: Anna Zettergren, Sara Karlsson, Erik Studer, Anna Sarvimäki, Petronella Kettunen, Annika Thorsell, Carina Sihlbom and Lars Westberg

    Citation: BMC Neuroscience 2017 18:9

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  3. Content type: Research article

    Previous neuroimaging studies have shown the hemodynamic effect of either preconditioning or postconditioning anesthesia in ischemic stroke model. However, the anesthetic effect in hemodynamics during and imm...

    Authors: Hongyang Lu, Yao Li, Bin Bo, Lu Yuan, Xiaodan Lu, Hangdao Li and Shanbao Tong

    Citation: BMC Neuroscience 2017 18:10

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  4. Content type: Research article

    Ultraviolet B irradiation confers strong resistance against experimental autoimmune encephalomyelitis, a model of multiple sclerosis. This protection by ultraviolet B is independent of vitamin D production but...

    Authors: Amy A. Irving, Steven J. Marling, Lori A. Plum and Hector F. DeLuca

    Citation: BMC Neuroscience 2017 18:8

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  5. Content type: Research article

    In view of age-related brain changes, identifying factors that are associated with healthy aging are of great interest. In the present study, we compared the functional brain network characteristics of three g...

    Authors: Julia C. Binder, Ladina Bezzola, Aurea I. S. Haueter, Carina Klein, Jürg Kühnis, Hansruedi Baetschmann and Lutz Jäncke

    Citation: BMC Neuroscience 2017 18:2

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  6. Content type: Research article

    Patients with medication-overuse headache suffer not only from chronic headache, but often from psychiatric comorbidities, such as anxiety and depression. The mechanisms underlying these comorbidities are uncl...

    Authors: Aree Wanasuntronwong, Ukkrit Jansri and Anan Srikiatkhachorn

    Citation: BMC Neuroscience 2017 18:1

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  7. Content type: Research Article

    Recording of motor evoked potentials (MEPs) is used during navigated transcranial magnetic stimulation (nTMS) motor mapping to locate motor function in the human brain. However, factors potentially underlying ...

    Authors: Nico Sollmann, Lucia Bulubas, Noriko Tanigawa, Claus Zimmer, Bernhard Meyer and Sandro M. Krieg

    Citation: BMC Neuroscience 2017 18:5

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  8. Content type: Research article

    Yawning is a stereotyped behavior that enhances blood flow to the skull, and the resulting counterflow has been hypothesized as a mechanism for brain cooling. Studies have shown that yawns are strongly associa...

    Authors: Jose R. Eguibar, Carlos A. Uribe, Carmen Cortes, Amando Bautista and Andrew C. Gallup

    Citation: BMC Neuroscience 2017 18:3

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  9. Content type: Research article

    Sugammadex (SGX) is a modified γ-cyclodextrin used for reversal of steroidal neuromuscular blocking agents during general anesthesia. Despite its application in clinical use, whether SGX treatment exerts any e...

    Authors: Hung-Te Hsu, Yi-Ching Lo, Yan-Ming Huang, Yu-Ting Tseng and Sheng-Nan Wu

    Citation: BMC Neuroscience 2017 18:6

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  10. Content type: Research Article

    A fundamental feature of early nervous system development is the guidance of axonal projections to their targets in order to assemble neural circuits that control behavior. Spinal commissural neurons are an at...

    Authors: Simon D. Sun, Ashley M. Purdy and Gregory S. Walsh

    Citation: BMC Neuroscience 2016 17:83

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  11. Content type: Research Article

    Diffusion magnetic resonance imaging (MRI) is the current-state-of-the-art technique to clinically investigate acute (0–24 h) ischemic stroke tissue. However, reduced apparent diffusion coefficient (ADC)—cons...

    Authors: Friedrich Wetterling, Eva Chatzikonstantinou, Laurent Tritschler, Stephen Meairs, Marc Fatar, Lothar R. Schad and Saema Ansar

    Citation: BMC Neuroscience 2016 17:82

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  12. Content type: Research Article

    It is known that tooth loss is known to be a risk factor for Alzheimer’s disease and soft diet feeding induces memory impairment. Recent studies have shown that brain-derived neurotrophic factor (BDNF) is asso...

    Authors: Yosuke Takeda, Hiroshi Oue, Shinsuke Okada, Akira Kawano, Katsunori Koretake, Makoto Michikawa, Yasumasa Akagawa and Kazuhiro Tsuga

    Citation: BMC Neuroscience 2016 17:81

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  13. Content type: Research Article

    Bone morphogenetic protein-2 (BMP-2) is a pleiotropic, secreted molecule with diverse effects. The potent ability of BMP-2 to stimulate bone growth prompted its widespread clinical use for arthrodesis (spine f...

    Authors: Kendall Mitchell, Jill P. Shah, Clifton L. Dalgard, Lyubov V. Tsytsikova, Ashley C. Tipton, Anton E. Dmitriev and Aviva J. Symes

    Citation: BMC Neuroscience 2016 17:80

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  14. Content type: Research Article

    α-Synuclein (αSYN) has been genetically implicated in familial and sporadic Parkinson’s disease (PD), and is associated with disease susceptibility, progression and pathology. Excess amounts of αSYN are toxic ...

    Authors: Tatsunori Maekawa, Toshikuni Sasaoka, Sadahiro Azuma, Takafumi Ichikawa, Heather L. Melrose, Matthew J. Farrer and Fumiya Obata

    Citation: BMC Neuroscience 2016 17:77

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  15. Content type: Research Article

    Myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) is a widely used animal model for multiple sclerosis. The characteristic feature of the MOG-EAE model in Brown...

    Authors: Sabine Herold, Prateek Kumar, Klaus Jung, Irina Graf, Henrike Menkhoff, Xenia Schulz, Mathias Bähr and Katharina Hein

    Citation: BMC Neuroscience 2016 17:78

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  16. Content type: Research Article

    Obsessive–compulsive disorder (OCD) is a chronic neurodevelopmental disorder that affects up to 3% of the general population. Although epigenetic mechanisms play a role in neurodevelopment disorders, epigenet...

    Authors: Carolina Cappi, Juliana Belo Diniz, Guaraci L. Requena, Tiaya Lourenço, Bianca Cristina Garcia Lisboa, Marcelo Camargo Batistuzzo, Andrea H. Marques, Marcelo Q. Hoexter, Carlos A. Pereira, Euripedes Constantino Miguel and Helena Brentani

    Citation: BMC Neuroscience 2016 17:79

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  17. Content type: Research article

    The neuropeptide arginine vasopressin (Avp) modulates social behaviors via its two centrally expressed receptors, the Avp 1a receptor and the Avp 1b receptor (Avpr1b). Recent work suggests that, at least in mi...

    Authors: Shannah K. Witchey, Erica L. Stevenson and Heather K. Caldwell

    Citation: BMC Neuroscience 2016 17:75

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  18. Content type: Research article

    Sleep disruptions are common in epilepsy patients. Our previous study demonstrates that homeostatic factors and circadian rhythm may mediate epilepsy-induced sleep disturbances when epilepsy occurs at differen...

    Authors: Tzu-Rung Huang, Shuo-Bin Jou, Yu-Ju Chou, Pei-Lu Yi, Chun-Jen Chen and Fang-Chia Chang

    Citation: BMC Neuroscience 2016 17:74

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  19. Content type: Review

    Epilepsy is one of the most common neurological diseases characterized by excessive hyperexcitability of neurons. Molecular mechanisms of epilepsy are diverse and not really understood. All in common is the mi...

    Authors: Helena F. Pernice, Rico Schieweck, Michael A. Kiebler and Bastian Popper

    Citation: BMC Neuroscience 2016 17:73

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  20. Content type: Research article

    The AP-2 transcription factor APTF-1 is crucially required for developmentally controlled sleep behavior in Caenorhabditis elegans larvae. Its human ortholog, TFAP-2beta, causes Char disease and has also been lin...

    Authors: Mariya M. Kucherenko, Vinodh Ilangovan, Bettina Herzig, Halyna R. Shcherbata and Henrik Bringmann

    Citation: BMC Neuroscience 2016 17:72

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  21. Content type: Methodology article

    Cone photoreceptors are specialised sensory retinal neurons responsible for photopic vision, colour perception and visual acuity. Retinal degenerative diseases are a heterogeneous group of eye diseases in whic...

    Authors: Antonino Glaviano, Andrew J. Smith, Alfonso Blanco, Sarah McLoughlin, Maria L. Cederlund, Theresa Heffernan, Beata Sapetto-Rebow, Yolanda Alvarez, Jun Yin and Breandán N. Kennedy

    Citation: BMC Neuroscience 2016 17:71

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  22. Content type: Research article

    Reinforcement learning is a fundamental form of learning that may be formalized using the Bellman equation. Accordingly an agent determines the state value as the sum of immediate reward and of the discounted ...

    Authors: Judit Zsuga, Klara Biro, Gabor Tajti, Magdolna Emma Szilasi, Csaba Papp, Bela Juhasz and Rudolf Gesztelyi

    Citation: BMC Neuroscience 2016 17:70

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  23. Content type: Research article

    Fused in sarcoma (FUS) is an RNA-binding protein associated with the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration. ALS manifests in patients as a progres...

    Authors: Kasey L. Jackson, Hemangini A. Dhaibar, Robert D. Dayton, Sergio G. Cananzi, William G. Mayhan, Edward Glasscock and Ronald L. Klein

    Citation: BMC Neuroscience 2016 17:69

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  24. Content type: Research article

    Transcranial focused ultrasound (FUS) is gaining momentum as a novel non-invasive brain stimulation method, with promising potential for superior spatial resolution and depth penetration compared to transcrani...

    Authors: Wonhye Lee, Yong An Chung, Yujin Jung, In-Uk Song and Seung-Schik Yoo

    Citation: BMC Neuroscience 2016 17:68

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  25. Content type: Research article

    The spatial resolution of repetitive navigated transcranial magnetic stimulation (rTMS) for language mapping is largely unknown. Thus, to determine a minimum spatial resolution of rTMS for language mapping, we...

    Authors: Nico Sollmann, Theresa Hauck, Lorena Tussis, Sebastian Ille, Stefanie Maurer, Tobias Boeckh-Behrens, Florian Ringel, Bernhard Meyer and Sandro M. Krieg

    Citation: BMC Neuroscience 2016 17:67

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  26. Content type: Research article

    Limited surveys have assessed the performance of 5-hydroxytreptamine receptor 1A and its antagonist WAY-100635 in pharmacological manipulations targeting delirium therapies. The purpose of this paper was to as...

    Authors: Yimin Qiu, Dongmei Chen, Xiaojing Huang, Lina Huang, Liang Tang, Jihong Jiang, Lianhua Chen and Shitong Li

    Citation: BMC Neuroscience 2016 17:66

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  27. Content type: Research article

    There is evidence that experimentally elicited auditory illusions in the general population index risk for psychotic symptoms. As little is known about underlying cortical mechanisms of auditory illusions, an ...

    Authors: E. Schepers, L. Bodar, J. van Os and R. Lousberg

    Citation: BMC Neuroscience 2016 17:65

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  28. Content type: Research article

    Cerebral oedema is closely related to the permeability of blood–brain barrier, vascular endothelial growth factor (VEGF) and its receptor vascular endothelial growth factor receptor 2 (VEGFR2) all of which are...

    Authors: Linqiang Huang, Wei Cao, Yiyu Deng, Gaofeng Zhu, Yongli Han and Hongke Zeng

    Citation: BMC Neuroscience 2016 17:64

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  29. Content type: Research article

    Larval zebrafish, with a simple and transparent vertebrate brain composed of ~100 K neurons, is well suited for deciphering entire neural circuit activity underlying behavior. Moreover, their small body size (...

    Authors: Yiming Bai, Harrison Liu, Bo Huang, Mahendra Wagle and Su Guo

    Citation: BMC Neuroscience 2016 17:63

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  30. Content type: Research article

    Bilateral adrenalectomy has been shown to damage the hippocampal neurons. Although the effects of long-term adrenalectomy have been studied extensively there are few publications on the effects of short-term a...

    Authors: Naserddine Hamadi, Azimullah Sheikh, Nather Madjid, Loai Lubbad, Naheed Amir, Safa Al-Deen Saudi Shehab, Fatima Khelifi-Touhami and Abdu Adem

    Citation: BMC Neuroscience 2016 17:61

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  31. Content type: Research article

    Astaxanthin is a carotenoid pigment that possesses potent antioxidative, anti-inflammatory, antitumor, and immunomodulatory activities. Previous studies have demonstrated that astaxanthin displays potential ne...

    Authors: Mingkun Zhang, Zhenwen Cui, Hua Cui, Yang Cao, Yong Wang and Chunlong Zhong

    Citation: BMC Neuroscience 2016 17:60

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  32. Content type: Research article

    Rehabilitation, which is essential for amputees with myoelectric hands, can improve the quality of daily life by remodeling the neuron network. In our study, we aim to develop a cerebral blood perfusion (CBF) ...

    Authors: Qiufang Liu, Xiujuan Zheng, Panli Li, Lian Xu, Longwen He, Zhao Mei, Yinyan Zhu, Gang Huang, Chunlong Zhong and Shaoli Song

    Citation: BMC Neuroscience 2016 17:59

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  33. Content type: Research article

    Parkinson disease (PD) is a movement disorder affecting 1 % of people over the age of 60. The etiology of the disease is unknown; however, accumulating evidence suggests that mitochondrial defects, oxidative s...

    Authors: Hayate Javed, Sheikh Azimullah, Salema B. Abul Khair, Shreesh Ojha and M. Emdadul Haque

    Citation: BMC Neuroscience 2016 17:58

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  34. Content type: Meeting abstracts

    A1 Functional advantages of cell-type heterogeneity in neural circuits

    Authors: Tatyana O. Sharpee, Alain Destexhe, Mitsuo Kawato, Vladislav Sekulić, Frances K. Skinner, Daniel K. Wójcik, Chaitanya Chintaluri, Dorottya Cserpán, Zoltán Somogyvári, Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett, Kresimir Josić, Irene Elices, David Arroyo, Rafael Levi…

    Citation: BMC Neuroscience 2016 17(Suppl 1):54

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    This article is part of a Supplement: Volume 17 Supplement 1

  35. Content type: Research article

    Mechanosensitive afferents innervating the bladder increase their firing rate as the bladder fills and pressure rises. However, the relationship between afferent firing rates and intravesical pressure is not a...

    Authors: Shani E. Ross, Zachariah J. Sperry, Colin M. Mahar and Tim M. Bruns

    Citation: BMC Neuroscience 2016 17:57

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  36. Content type: Research article

    Recurrent convulsions can cause irreversible astrocyte death, impede neuron regeneration, and further aggravate brain damage. MicroRNAs have been revealed as players in the progression of numerous diseases inc...

    Authors: Liqun Liu, Lingjuan Liu, Jiayun Shi, Menglin Tan, Jie Xiong, Xingfang Li, Qingpeng Hu, Zhuwen Yi and Ding’an Mao

    Citation: BMC Neuroscience 2016 17:56

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  37. Content type: Research article

    Understanding the relationship between a stimulus and how it is perceived reveals fundamental principles about the mechanisms of sensory perception. While this stimulus-percept problem is mostly understood for...

    Authors: Andreas Keller and Leslie B. Vosshall

    Citation: BMC Neuroscience 2016 17:55

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  38. Content type: Research article

    Polymorphisms in the gene for phosphatidylinositol binding clathrin assembly protein (PICALM), an endocytic-related protein, are associated with a small, increased risk of developing Alzheimer’s disease (AD), ...

    Authors: Rhian S. Thomas, Alex Henson, Amy Gerrish, Lesley Jones, Julie Williams and Emma J. Kidd

    Citation: BMC Neuroscience 2016 17:50

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  39. Content type: Research article

    Amyloid-beta (Aβ) accumulation is a hallmark of Alzheimer’s disease (AD) that can lead to neuronal dysfunction and apoptosis. Tumor necrosis factor, alpha-induced protein 1 (TNFAIP1) is an apoptotic protein th...

    Authors: Ning Liu, Zhanyang Yu, Yu Xun, Miaomiao Li, Xiaoning Peng, Ye Xiao, Xiang Hu, Yi Sun, Manjun Yang, Shiquan Gan, Shishan Yuan, Xiaoying Wang, Shuanglin Xiang and Jian Zhang

    Citation: BMC Neuroscience 2016 17:51

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  40. Content type: Research article

    Perivascular stromal cells (PSCs) are a recently identified cell type that comprises a small percentage of the platelet derived growth factor receptor-β+ cells within the CNS perivascular space. PSCs are activ...

    Authors: Kathleen K. Kelly, Amber M. MacPherson, Himmat Grewal, Frank Strnad, Jace W. Jones, Jianshi Yu, Keely Pierzchalski, Maureen A. Kane, Paco S. Herson and Julie A. Siegenthaler

    Citation: BMC Neuroscience 2016 17:49

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  41. Content type: Methodology article

    In many functional magnetic resonance imaging (fMRI) studies, experimental design often depends on the eye state (i.e., whether the participants had their eyes open or closed). Closed eyes during an fMRI is th...

    Authors: Stefan Brodoehl, Otto W. Witte and Carsten M. Klingner

    Citation: BMC Neuroscience 2016 17:48

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  42. Content type: Research article

    Peripheral neuropathy is a common and dose-limiting side effect of many cancer chemotherapies. The taxane agents, including paclitaxel (Taxol®), are effective chemotherapeutic drugs but cause degeneration of pred...

    Authors: Aniqa Tasnim, Zoe Rammelkamp, Amy B. Slusher, Krystyna Wozniak, Barbara S. Slusher and Mohamed H. Farah

    Citation: BMC Neuroscience 2016 17:47

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  43. Content type: Research article

    We previously reported the production of transgenic rats (APP21 line) that over-express human amyloid precursor protein (APP) containing Swedish and Indiana mutations. In order to generate a better model for A...

    Authors: Cansu Agca, Diana Klakotskaia, Todd R. Schachtman, Anthony W. Chan, James J. Lah and Yuksel Agca

    Citation: BMC Neuroscience 2016 17:46

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  44. Content type: Research article

    Recent research has documented structural brain abnormalities in various criminal offenders. However, there have been few brain imaging studies of sex offenders, and none on white matter integrity. The curren...

    Authors: Chiao-Yun Chen, Adrian Raine, Kun-Hsien Chou, I-Yun Chen, Daisy Hung and Ching-Po Lin

    Citation: BMC Neuroscience 2016 17:45

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  45. Content type: Research article

    Murine models of Alzheimer’s disease (AD) are mainly based on overexpression of pathologic amyloid precursor protein and/or presenilins. Those genes resemble underlying cause of early onset type of AD while ab...

    Authors: Kristina Endres, Sven Reinhardt, Anastasia Geladaris, Julia Knies, Marcus Grimm, Tobias Hartmann and Ulrich Schmitt

    Citation: BMC Neuroscience 2016 17:44

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