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  1. The SCN11A gene, encoded Nav1.9 TTX resistant sodium channels, is a main effector in peripheral inflammation related pain in nociceptive neurons. The role of SCN11A gene in the auditory system has not been well c...

    Authors: Mian Zu, Wei-Wei Guo, Tao Cong, Fei Ji, Shi-Li Zhang, Yue Zhang, Xin Song, Wei Sun, David Z. Z. He, Wei-Guo Shi and Shi-Ming Yang
    Citation: BMC Neuroscience 2021 22:18
  2. Several studies have shown that glutamate neurotransmission in the nucleus accumbens (NAc) is required for the development of morphine-induced conditional place preference (CPP). In addition, metabotropic glut...

    Authors: Zahra Ebrahimi, Nazanin Kahvandi, Alireza Komaki, Seyed Asaad Karimi, Marzieh Naderishahab and Abdolrahman Sarihi
    Citation: BMC Neuroscience 2021 22:17
  3. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Laszlo Szpisjak, Gabor Szaraz, Andras Salamon, Viola L. Nemeth, Noemi Szepfalusi, Gabor Veres, Balint Kincses, Zoltan Maroti, Tibor Kalmar, Malgorzata Rydzanicz, Rafal Ploski, Peter Klivenyi and Denes Zadori
    Citation: BMC Neuroscience 2021 22:16

    The original article was published in BMC Neuroscience 2021 22:7

  4. Rupture of intracranial aneurysm (IA) is the main cause of devastating subarachnoid hemorrhage, which urges our understanding of the pathogenesis and regulatory mechanisms of IA. However, the regulatory roles ...

    Authors: Yuan-Bo Pan, Jianan Lu, Biao Yang, Cameron Lenahan, Jianmin Zhang and Anwen Shao
    Citation: BMC Neuroscience 2021 22:15
  5. Alzheimer’s disease (AD) is characterized by cognitive impairment that eventually develops into dementia. Amyloid-beta (Aβ) accumulation is a widely described hallmark in AD, and has been reported to cause olf...

    Authors: Mara A. Guzmán-Ruiz, Amor Herrera-González, Adriana Jiménez, Alan Candelas-Juárez, Crystal Quiroga-Lozano, Claudia Castillo-Díaz, Erika Orta-Salazar, Diana Organista-Juárez, Sofía Díaz-Cintra and Rosalinda Guevara-Guzmán
    Citation: BMC Neuroscience 2021 22:14

    The Correction to this article has been published in BMC Neuroscience 2021 22:27

  6. Aside from the homeostatic and circadian components, light has itself an important, direct as well as indirect role in sleep regulation. Light exerts indirect sleep effect by modulating the circadian rhythms. ...

    Authors: Örs Szalontai, Attila Tóth, Máté Pethő, Dóra Keserű, Tünde Hajnik and László Détári
    Citation: BMC Neuroscience 2021 22:13
  7. Men and women show differences in sensitivity to reward and punishment, which may impact behavior in health and disease. However, the neural bases of these sex differences remain under-investigated. Here, by c...

    Authors: Isha Dhingra, Sheng Zhang, Simon Zhornitsky, Wuyi Wang, Thang M. Le and Chiang-Shan R. Li
    Citation: BMC Neuroscience 2021 22:12
  8. Attachment theory demonstrates that early attachment experience shapes internal working models with mental representations of self and close relationships, which affects personality traits and interpersonal re...

    Authors: Min Deng, Xing Zhang, Xiaoyan Bi and Chunhai Gao
    Citation: BMC Neuroscience 2021 22:11
  9. There is growing evidence for a positive correlation between measures of muscular strength and cognitive abilities. However, the neurophysiological correlates of this relationship are not well understood so fa...

    Authors: Fabian Herold, Tom Behrendt, Alexander Törpel, Dennis Hamacher, Notger G. Müller and Lutz Schega
    Citation: BMC Neuroscience 2021 22:10
  10. We previously reported that heat shock protein 27 (HSP27) phosphorylation plays an important role in the activation of glucose-6-phosphate dehydrogenase (G6PD), resulting in the upregulation of the pentose pho...

    Authors: Kazuya Matsuo, Kohkichi Hosoda, Jun Tanaka, Yusuke Yamamoto, Taichiro Imahori, Tomoaki Nakai, Yasuhiro Irino, Masakazu Shinohara, Takashi Sasayama and Eiji Kohmura
    Citation: BMC Neuroscience 2021 22:9
  11. It has been shown that eosinophils are decreased and monocytes are elevated in patients with acute ischemic stroke (AIS), but the impact of eosinophil-to-monocyte ratio (EMR) on clinical outcomes among AIS pat...

    Authors: Shuhong Yu, Yi Luo, Tan Zhang, Chenrong Huang, Yu Fu, Qiang Zhang, Fangyue Zeng, Hao Huang, Chunyuan Zhang and Zhiliang Guo
    Citation: BMC Neuroscience 2021 22:8
  12. SYNE1 ataxia is an autosomal recessive hereditary condition, the main characteristic features of which are gait and limb ataxia and cerebellar dysarthria. Reports have revealed that the clinical phenotype of SYNE...

    Authors: Laszlo Szpisjak, Gabor Szaraz, Andras Salamon, Viola L. Nemeth, Noemi Szepfalusi, Gabor Veres, Balint Kincses, Zoltan Maroti, Tibor Kalmar, Malgorzata Rydzanicz, Rafal Ploski, Peter Klivenyi and Denes Zadori
    Citation: BMC Neuroscience 2021 22:7

    The Correction to this article has been published in BMC Neuroscience 2021 22:16

  13. Neuropathic pain (NeuP) is a complex, debilitating condition of the somatosensory system, where dysregulation between pro- and anti-inflammatory cytokines and chemokines are believed to play a pivotal role. As...

    Authors: Mika Jönsson, Björn Gerdle, Bijar Ghafouri and Emmanuel Bäckryd
    Citation: BMC Neuroscience 2021 22:6
  14. The Period Circadian Regulator 2 (Per2) gene is important for the modulation of circadian rhythms that influence biological processes. Circadian control of the hypothalamus-pituitary-adrenal (HPA) axis is critica...

    Authors: Ashley L. Russell, Lauren Miller, Hannah Yi, Rita Keil, Robert J. Handa and T. John Wu
    Citation: BMC Neuroscience 2021 22:5
  15. Astrocytes are responsible for a broad range of functions that maintain homeostasis in the brain. However, their response to the pro-inflammatory cytokines released by activated microglia in various neurologic...

    Authors: Emilia Zgórzyńska, Dawid Stulczewski, Barbara Dziedzic, Kuan-Pin Su and Anna Walczewska
    Citation: BMC Neuroscience 2021 22:4
  16. Status epilepticus (SE) is a life-threatening neurological disorder. The hippocampus, as an important area of the brain that regulates cognitive function, is usually damaged after SE, and cognitive deficits of...

    Authors: Xin-Ming Luo, Jing Zhao, Wen-Yue Wu, Jie Fu, Zheng-Yu Li, Ming Zhang and Jie Lu
    Citation: BMC Neuroscience 2021 22:2
  17. A common problem in neurophysiological signal processing is the extraction of meaningful information from high dimension, low sample size data (HDLSS). We present RoLDSIS (regression on low-dimension spanned i...

    Authors: Adrielle C. Santana, Adriano V. Barbosa, Hani C. Yehia and Rafael Laboissière
    Citation: BMC Neuroscience 2021 22:1
  18. Conditioned pain modulation (CPM) evaluates the effect of a painful conditioning stimulus (CS) on a painful test stimulus (TS). Using painful cutaneous electrical stimulation (PCES) as TS and painful cold wate...

    Authors: A. T. L. Do, E. K. Enax-Krumova, Ö. Özgül, L. B. Eitner, S. Heba, M. Tegenthoff, C. Maier and O. Höffken
    Citation: BMC Neuroscience 2020 21:53
  19. Ventromedial hypothalamic nucleus (VMN) gluco-regulatory transmission is subject to sex-specific control by estradiol. The VMN is characterized by high levels of aromatase expression.

    Authors: Md. Main Uddin, Mostafa M. H. Ibrahim and Karen P. Briski
    Citation: BMC Neuroscience 2020 21:51
  20. Transcription factor 4 (TCF4) has been linked to human neurodevelopmental disorders such as intellectual disability, Pitt-Hopkins Syndrome (PTHS), autism, and schizophrenia. Recent work demonstrated that TCF4 par...

    Authors: Katharina Braun, Benjamin M. Häberle, Marie-Theres Wittmann and D. Chichung Lie
    Citation: BMC Neuroscience 2020 21:50
  21. Previous studies have demonstrated that individuals with autism spectrum disorder (ASD) exhibit dysfunction in the three attention systems (i.e., alerting, orienting, and executive control) as well as atypical re...

    Authors: Sayaka Yoshimura, Kei Kobayashi, Tsukasa Ueno, Takashi Miyagi, Naoya Oishi, Toshiya Murai and Hironobu Fujiwara
    Citation: BMC Neuroscience 2020 21:49
  22. To identify mechanisms of cortical plasticity of the visual cortex and to quantify their significance, sensitive parameters are warranted. In this context, multifocal visual evoked potentials (mfVEPs) can make...

    Authors: Robert Kolbe, Aykut Aytulun, Ann-Kristin Müller, Marius Ringelstein, Orhan Aktas, Alfons Schnitzler, Hans-Peter Hartung, Stefan Jun Groiss and Philipp Albrecht
    Citation: BMC Neuroscience 2020 21:48
  23. We present first-time evidence for the immediate neural and behavioral effects of bifocal emotional processing via visualized tapping for two different types of negative emotions (fear and disgust) in a sample...

    Authors: Dina Wittfoth, Antonia Pfeiffer, Michael Bohne, Heinrich Lanfermann and Matthias Wittfoth
    Citation: BMC Neuroscience 2020 21:47
  24. As a noninvasive perfusion-weighted MRI technique, arterial spin-labeling (ASL) was becoming increasingly used to evaluate cerebral hemodynamics in many studies. The relation between ASL-MRI and crossed cerebe...

    Authors: Juan Wang, Li-Jun Pan, Bin Zhou, Jin-Yan Zu, Yi-Xu Zhao, Yang Li, Wan-Qiu Zhu, Lei Li, Jian-Rong Xu and Zeng-Ai Chen
    Citation: BMC Neuroscience 2020 21:46
  25. Cardiac arrest (CA) is the most common cause of acute neurologic insult in children. Many survivors have significant neurocognitive deficits at 1 year of recovery. Epoxyeicosatrienoic acids (EETs) are multifun...

    Authors: Caitlin E. O’Brien, Polan T. Santos, Ewa Kulikowicz, Jennifer K. Lee, Raymond C. Koehler and Lee J. Martin
    Citation: BMC Neuroscience 2020 21:43
  26. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative fatal disease that can affect the neurons of brain and spinal cord. ALS genetics has identified various genes to be associated with diseas...

    Authors: Surinder Pal, Abha Tiwari, Kaushal Sharma and Suresh Kumar Sharma
    Citation: BMC Neuroscience 2020 21:42
  27. During voluntary muscle contraction, sensory information induced by electrostimulation of the nerves supplying the contracting muscle is inhibited and the somatosensory evoked potentials (SEPs) amplitude decre...

    Authors: Terumasa Takahara, Hidetaka Yamaguchi, Kazutoshi Seki and Sho Onodera
    Citation: BMC Neuroscience 2020 21:41
  28. Serotonin is a neurotransmitter that has been linked to a wide variety of behaviors including feeding and body-weight regulation, social hierarchies, aggression and suicidality, obsessive compulsive disorder, ...

    Authors: Janet Best, William Duncan, Farrah Sadre-Marandi, Parastoo Hashemi, H. Frederik Nijhout and Michael Reed
    Citation: BMC Neuroscience 2020 21:40
  29. ADHD is one of the most common psychiatric disorders in children and adolescents. Altered functional connectivity has been associated with ADHD symptoms. This study aimed to investigate abnormal changes in the...

    Authors: Huayu Zhang, Yue Zhao, Weifang Cao, Dong Cui, Qing Jiao, Weizhao Lu, Hongyu Li and Jianfeng Qiu
    Citation: BMC Neuroscience 2020 21:39
  30. Glucose fluctuation promotes neuronal apoptosis, which plays a central role in diabetic encephalopathy (DE). Nerve growth factor (NGF), and its interaction with high-affinity (TrkA) and low-affinity (p75NTR) r...

    Authors: Ting Yan, Zhihui Zhang and Danqing Li
    Citation: BMC Neuroscience 2020 21:38
  31. Although previous studies have shown that intra-network abnormalities in brain functional networks are correlated with clinical/cognitive impairment in multiple sclerosis (MS), there is little information rega...

    Authors: Lin Wu, Muhua Huang, Fuqing Zhou, Xianjun Zeng and Honghan Gong
    Citation: BMC Neuroscience 2020 21:37
  32. Frontotemporal dementia (FTD) is the second leading cause of early onset dementia following Alzheimer’s disease. It involves atrophy of the frontal and temporal regions of the brain affecting language, memory,...

    Authors: Lalitha Venkataraman, Ping He, Galam Khan, Brent T. Harris and Michael R. Sierks
    Citation: BMC Neuroscience 2020 21:36
  33. The inter-scanner reproducibility of brain volumetry is important in multi-site neuroimaging studies, where the reliability of automated brain segmentation (ABS) tools plays an important role. This study aimed...

    Authors: Sirui Liu, Bo Hou, Yiwei Zhang, Tianye Lin, Xiaoyuan Fan, Hui You and Feng Feng
    Citation: BMC Neuroscience 2020 21:35
  34. When planning nerve conduction studies using animal models, the sciatic nerve is often used and the upper extremity nerves are not preferred due to the size of laboratory animals. This study aimed to present t...

    Authors: Basak Mansiz-Kaplan, Secil Pervane-Vural, Koray Gursoy and Baris Nacir
    Citation: BMC Neuroscience 2020 21:34
  35. Alzheimer’s disease (AD) is a progressive neuro-degenerative disease with a major manifestation of dementia. MicroRNAs were reported to regulate the transcript expression in patients with Alzheimer’s disease (...

    Authors: Jin Miao, Jin Jing, Yixiang Shao and Huaichang Sun
    Citation: BMC Neuroscience 2020 21:33
  36. Recent research has revealed that the community of microorganisms inhabiting the gut affects brain development, function and behaviour. In particular, disruption of the gut microbiome during critical developme...

    Authors: Katerina V. A. Johnson and Philip W. J. Burnet
    Citation: BMC Neuroscience 2020 21:32
  37. Parkinson’s disease (PD) is a disease of the central nervous system that progressively affects the motor system. Epidemiological studies have provided evidence that exposure to agriculture-related occupations ...

    Authors: Rodney C. P. Go, Michael J. Corley, G. Webster Ross, Helen Petrovitch, Kamal H. Masaki, Alika K. Maunakea, Qimei He and Maarit I. Tiirikainen
    Citation: BMC Neuroscience 2020 21:31
  38. One of the most basic human traits is language. Linguistic ability, and disability, have been shown to have a strong genetic component in family and twin studies, but molecular genetic studies of language phen...

    Authors: Ron Nudel, Camilla A. J. Christiani, Jessica Ohland, Md Jamal Uddin, Nicoline Hemager, Ditte Ellersgaard, Katrine S. Spang, Birgitte K. Burton, Aja N. Greve, Ditte L. Gantriis, Jonas Bybjerg-Grauholm, Jens Richardt M. Jepsen, Anne A. E. Thorup, Ole Mors, Thomas Werge and Merete Nordentoft
    Citation: BMC Neuroscience 2020 21:30
  39. Hypoxia inhibits the uptake of glutamate (a major neurotransmitter in the brain closely related to cognitive function) into brain cells, and the initial response of cells to cortical hypoxia depends on glutama...

    Authors: Young-Sung Kim, Young Ju Won, Byung Gun Lim, Too Jae Min, Yeon-Hwa Kim and Il Ok Lee
    Citation: BMC Neuroscience 2020 21:29
  40. Precise regulation of neural precursor cell (NPC) proliferation and differentiation is essential to ensure proper brain development and function. The HCFC1 gene encodes a transcriptional co-factor that regulates ...

    Authors: Victoria L. Castro, Joel F. Reyes, Nayeli G. Reyes-Nava, David Paz and Anita M. Quintana
    Citation: BMC Neuroscience 2020 21:27
  41. Cerebral stroke occurs following ischemic and hemorrhagic lesions in the brain. Survival and recovery of stroke patients depend on the severity of the initial injury but also the therapeutic approaches applied...

    Authors: Ewen Tu, Qiong Chen, Li Tan and Yan Wang
    Citation: BMC Neuroscience 2020 21:24
  42. Alexithymia is a personality trait characterized by difficulties identifying and describing feelings, an externally oriented style of thinking, and a reduced inclination to imagination. Previous research has s...

    Authors: Nicole Rosenberg, Klas Ihme, Vladimir Lichev, Julia Sacher, Michael Rufer, Hans Jörgen Grabe, Harald Kugel, André Pampel, Jöran Lepsien, Anette Kersting, Arno Villringer and Thomas Suslow
    Citation: BMC Neuroscience 2020 21:23

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