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  1. Content type: Review

    Optogenetics has become widely recognized for its success in real-time control of brain neurons by utilizing non-mammalian photosensitive proteins to open or close membrane channels. Here we review a less well...

    Authors: Oksana Polesskaya, Ancha Baranova, Sarah Bui, Nikolai Kondratev, Evgeniya Kananykhina, Olga Nazarenko, Tatyana Shapiro, Frances Barg Nardia, Vladimir Kornienko, Vikas Chandhoke, Istvan Stadler, Raymond Lanzafame and Max Myakishev-Rempel

    Citation: BMC Neuroscience 2018 19(Suppl 1):12

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  2. Content type: Research

    APOE ε4 allele is most common genetic risk factor for Alzheimer’s disease (AD) and cognitive decline. However, it remains poorly understood why only some carriers of APOE ε4 develop AD and how ethnic variabilitie...

    Authors: Vladimir N. Babenko, Dmitry A. Afonnikov, Elena V. Ignatieva, Anton V. Klimov, Fedor E. Gusev and Evgeny I. Rogaev

    Citation: BMC Neuroscience 2018 19(Suppl 1):16

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  3. Content type: Research article

    Stroke is among the leading causes of death and disability. Although intense research efforts have provided promising treatment options in animals, most clinical trials in humans have failed and the therapeuti...

    Authors: Edvin Ingberg, Hua Dock, Elvar Theodorsson, Annette Theodorsson and Jakob O. Ström

    Citation: BMC Neuroscience 2018 19:24

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  4. Content type: Research article

    Numerous studies have investigated the neural underpinnings of passive and active deviance and target detection in the well-known auditory oddball paradigm by means of event-related potentials (ERPs) or functiona...

    Authors: Christoph Justen and Cornelia Herbert

    Citation: BMC Neuroscience 2018 19:25

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  5. Content type: Research

    The dominant hypothesis about the pathogenesis of Alzheimer’s disease (AD) is the “amyloid cascade” concept and modulating the expression of proteins involved in the metabolism of amyloid-beta (Aβ) is propose...

    Authors: Maria A. Tikhonova, Tamara G. Amstislavskaya, Victor M. Belichenko, Larisa A. Fedoseeva, Sergey P. Kovalenko, Ekaterina E. Pisareva, Alla S. Avdeeva, Nataliya G. Kolosova, Nikolai D. Belyaev and Lyubomir I. Aftanas

    Citation: BMC Neuroscience 2018 19(Suppl 1):13

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  6. Content type: Research

    A challenge of understanding the mechanisms underlying cognition including neurodevelopmental and neuropsychiatric disorders is mainly given by the potential severity of cognitive disorders for the quality of ...

    Authors: Leonid O. Bryzgalov, Elena E. Korbolina, Ilja I. Brusentsov, Elena Y. Leberfarb, Natalia P. Bondar and Tatiana I. Merkulova

    Citation: BMC Neuroscience 2018 19(Suppl 1):22

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  7. Content type: Research article

    Apoptotic changes after cerebral hemorrhage in brain samples of humans have been found. Caspase-cleaved cytokeratin (CCCK)-18 could be detected in the bloodstream during apoptosis. Higher circulating CCCK-18 l...

    Authors: Leonardo Lorente, María M. Martín, Antonia Pérez-Cejas, Luis Ramos, Mónica Argueso, Jordi Solé-Violán, Juan J. Cáceres, Alejandro Jiménez and Victor García-Marín

    Citation: BMC Neuroscience 2018 19:23

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  8. Content type: Research article

    Stroke is a leading cause of death and disability worldwide, yet there are limited treatments available. Intranasal administration is a novel non-invasive strategy to deliver cell therapy into the brain. Cell...

    Authors: Monica J. Chau, Todd C. Deveau, Xiaohuan Gu, Yo Sup Kim, Yun Xu, Shan Ping Yu and Ling Wei

    Citation: BMC Neuroscience 2018 19:20

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  9. Content type: Research article

    Cerebrovascular reactivity (CVR) refers to the responsiveness of cerebral vasculature to vasoactive stimuli. CVR is an indicator of brain health and can be assessed using vasodilatory techniques and magnetic r...

    Authors: Sarah J. Catchlove, Andrew Pipingas, Matthew E. Hughes and Helen Macpherson

    Citation: BMC Neuroscience 2018 19:21

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  10. Content type: Research article

    Autonomic nervous system (ANS) activity has been shown to vary with the state of brain arousal. In a previous study, this association of ANS activity with distinct states of brain arousal was demonstrated usin...

    Authors: Jue Huang, Christine Ulke, Christian Sander, Philippe Jawinski, Janek Spada, Ulrich Hegerl and Tilman Hensch

    Citation: BMC Neuroscience 2018 19:18

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  11. Content type: Research article

    Accumulation of the α-synuclein (α-syn) protein is a hallmark of a group of brain disorders collectively known as synucleinopathies. The mechanisms responsible for α-syn accumulation are not well understood. S...

    Authors: Jared Schommer, Gurdeep Marwarha, Trevor Schommer, Travis Flick, Jonah Lund and Othman Ghribi

    Citation: BMC Neuroscience 2018 19:17

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  12. Content type: Research article

    Chronic opioid therapy for non-malignant pain conditions has significantly increased over the last 15 years. Recently, the correlation between opioid analgesics and alternations in brain structure, such as leu...

    Authors: Ruping Fan, Lisa M. Schrott, Thomas Arnold, Stephen Snelling, Meghana Rao, Derrel Graham, Angela Cornelius and Nadejda L. Korneeva

    Citation: BMC Neuroscience 2018 19:15

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  13. Content type: Methodology article

    Amyotrophic lateral sclerosis (ALS) is a clinically and histopathologically heterogeneous neurodegenerative disorder, in which therapy is hindered by the rapid progression of disease and lack of biomarkers. Ma...

    Authors: Menuka Pallebage-Gamarallage, Sean Foxley, Ricarda A. L. Menke, Istvan N. Huszar, Mark Jenkinson, Benjamin C. Tendler, Chaoyue Wang, Saad Jbabdi, Martin R. Turner, Karla L. Miller and Olaf Ansorge

    Citation: BMC Neuroscience 2018 19:11

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  14. Content type: Research article

    Labor subjects the fetus to an hypoxic episode and concomitant adrenomodullary catecholamine surge that may provide protection against the hypoxic insult. The beta1-adrenergic agonist dobutamine protects again...

    Authors: Tina Markus, David Ley, Stefan R. Hansson, Tadeusz Wieloch and Karsten Ruscher

    Citation: BMC Neuroscience 2018 19:9

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  15. Content type: Research article

    Sleep deprivation impairs learning, causes stress, and can lead to death. Notch and JNK-1 pathways impact C. elegans sleep in complex ways; these have been hypothesized to involve compensatory sleep. C. elegans D...

    Authors: Heather L. Bennett, Yulia Khoruzhik, Dustin Hayden, Huiyan Huang, Jarred Sanders, Melissa B. Walsh, David Biron and Anne C. Hart

    Citation: BMC Neuroscience 2018 19:10

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  16. Content type: Software

    Quantification of axon regeneration in spinal cord tissue sections is a fundamental step to adequately determine if an applied treatment leads to an anatomical benefit following spinal cord injury. Recent adva...

    Authors: Akash Patel, Zhongzhi Li, Philip Canete, Hans Strobl, Jennifer Dulin, Ken Kadoya, Dan Gibbs and Gunnar H. D. Poplawski

    Citation: BMC Neuroscience 2018 19:8

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  17. Content type: Research article

    Understanding the process of relapse to abused drugs and ultimately developing treatments that can reduce the incidence of relapse remains the primary goal for the study of substance dependence. Therefore, exp...

    Authors: Tingting Ning, Changlong Leng, Lin Chen, Baomiao Ma and Xiaokang Gong

    Citation: BMC Neuroscience 2018 19:4

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  18. Content type: Research article

    Neuroinflammation and the presence of amyloid beta protein (Aβ) and neurofibrillary tangles are key pathologies in Alzheimer’s disease (AD). As a potent anti-amyloid and anti-inflammatory natural polyphenol, c...

    Authors: Panchanan Maiti, Leela Paladugu and Gary L. Dunbar

    Citation: BMC Neuroscience 2018 19:7

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  19. Content type: Methodology article

    Brain pericytes ensheathe the endothelium and contribute to formation and maintenance of the blood–brain-barrier. Additionally, pericytes are involved in several aspects of the CNS immune response including sc...

    Authors: Justin Rustenhoven, Leon C. Smyth, Deidre Jansson, Patrick Schweder, Miranda Aalderink, Emma L. Scotter, Edward W. Mee, Richard L. M. Faull, Thomas I.-H. Park and Mike Dragunow

    Citation: BMC Neuroscience 2018 19:6

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  20. Content type: Research article

    The recent Zika virus (ZIKV) outbreak has linked ZIKV with microcephaly and other central nervous system pathologies in humans. Astrocytes are among the first cells to respond to ZIKV infection in the brain an...

    Authors: Michal Stefanik, Petra Formanova, Tomas Bily, Marie Vancova, Ludek Eyer, Martin Palus, Jiri Salat, Carla Torres Braconi, Paolo M. de A. Zanotto, Ernest A. Gould and Daniel Ruzek

    Citation: BMC Neuroscience 2018 19:5

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  21. Content type: Research article

    Real-time reverse transcription quantitative polymerase chain reaction (RT-qPCR) is a critical tool for evaluating the levels of mRNA transcribed from genes. Reliable RT-qPCR results largely depend on normaliz...

    Authors: Yingbo Kang, Zhuomin Wu, De Cai and Binger Lu

    Citation: BMC Neuroscience 2018 19:3

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  22. Content type: Research article

    Alzheimer’s disease (AD) is characterized by the deposition of amyloid-β (Aβ) in brain parenchyma and cerebral blood vessels as cerebral amyloid angiopathy (CAA). Clusterin, a chaperon protein associated with ...

    Authors: Xue-Mei Qi, Cheng Wang, Xing-Kun Chu, Gen Li and Jian-Fang Ma

    Citation: BMC Neuroscience 2018 19:2

    Published on:

Page 1 of 179

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