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  1. Obstructive sleep apnea (OSA) is mainly characterized by sleep fragmentation and chronic intermittent hypoxia (CIH), the latter one being associated with multiple organ injury. Recently, OSA-induced cognition ...

    Authors: Ningning She, Yewen Shi, Yani Feng, Lina Ma, Yuqi Yuan, Yitong Zhang, Zine Cao, Xi Chen, Bingjie Zhao, Haiqin Liu and Xiaoyong Ren
    Citation: BMC Neuroscience 2022 23:70
  2. Arginine-Vasopressin (AVP) is a nonapeptide that exerts multiple functions within the central nervous system and in the blood circulation that might contribute to outcome in critically ill patients. Sex differ...

    Authors: A. H. Podtschaske, J. Martin, B. Ulm, B. Jungwirth and S. M. Kagerbauer
    Citation: BMC Neuroscience 2022 23:69
  3. The multicomponent drug Neurexan (Nx4) was shown to reduce the neural stress network activation. We now investigated its effects on stress-induced resting state functional connectivity (RSFC) in dependence of ...

    Authors: Melanni Nanni-Zepeda, Sarah Alizadeh, Tara Chand, Vanessa Kasties, Yan Fan, Johan van der Meer, Luisa Herrmann, Johannes C. Vester, Myron Schulz, Britta Naschold and Martin Walter
    Citation: BMC Neuroscience 2022 23:68
  4. Esketamine upregulates Zn2+-dependent matrix metalloproteinase 9 (MMP9) and increases the neuronal apoptosis in retinal ganglion cell layer during the early development. We aimed to test whether albumin can allev...

    Authors: Kan Zhang, Ruijing Ma, Luping Feng, Peiwen Liu, Shuang Cai, Chaoyang Tong and Jijian Zheng
    Citation: BMC Neuroscience 2022 23:66
  5. One of the most serious nervous system diseases is spinal cord injury(SCI), which is increasing for various reasons. Although no definitive treatment has yet been identified for SCI, one possible treatment is ...

    Authors: Arvin Naeimi, Arash Zaminy, Naser Amini, Raziye Balabandi and Zoleikha Golipoor
    Citation: BMC Neuroscience 2022 23:65
  6. The pathogenesis of neuropathic pain (NP) has not been fully elucidated. Gene changes in dorsal root ganglia (DRG) may contribute to the development of NP. Circular RNAs (circRNAs) are a class of endogenous no...

    Authors: Wanxia Xiong, Min Wei, Li Zhang, Jie Wang, Fan Liu and Zhiyao Wang
    Citation: BMC Neuroscience 2022 23:64
  7. Retinal ganglion cells (RGCs) are important retinal neurons that connect visual receptors to the brain, and lysine-specific demethylase 1 (LSD1) is implicated in the development of RGCs. This study expounded t...

    Authors: Xiuling Yu, Tongtong Niu and Chi Liu
    Citation: BMC Neuroscience 2022 23:63
  8. Inflammation and glutamate (GLU) are widely thought to participate in the pathogenesis of depression, and current evidence suggests that the development of depression is associated with the activation of the k...

    Authors: Xingying Wu, Bowen Chen, Zhong Di, Shuo Jiang, Haipeng Xu, Mengting Shi, Rong Hu, Shaopeng Sun, Zhujin Song, Jiapeng Liu, Ruijie Ma and Qin Guo
    Citation: BMC Neuroscience 2022 23:62
  9. In brain, microvascular endothelial cells are exposed to various forces, including shear stress (SS). However, little is known about the effects of high shear stress (HSS) on human brain microvascular endothel...

    Authors: Zhe Li, Jia-Nan Li, Qiang Li, Chun Liu, Lin-Hua Zhou, Qi Zhang and Yi Xu
    Citation: BMC Neuroscience 2022 23:61
  10. Chondroitinase ABC (chABC) is an enzyme could improve regeneration and thereby improving functional recovery of spinal cord injury (SCI) in rodent models. Degradation of the active enzyme and diffusion away fr...

    Authors: Atousa Sharifi, Ali Zandieh, Zahra Behroozi, Michael R. Hamblin, Sara Mayahi, Mahmoud Yousefifard and Fatemeh Ramezani
    Citation: BMC Neuroscience 2022 23:60
  11. The hooded seal (Cystophora cristata) exhibits impressive diving skills and can tolerate extended durations of asphyxia, hypoxia and oxidative stress, without suffering from irreversible neuronal damage. Thus, wh...

    Authors: Gerrit A. Martens, Cornelia Geßner, Carina Osterhof, Thomas Hankeln and Thorsten Burmester
    Citation: BMC Neuroscience 2022 23:59
  12. Opioids are among the most effective and commonly prescribed analgesics for the treatment of acute pain after spinal cord injury (SCI). However, morphine administration in the early phase of SCI undermines loc...

    Authors: Mabel N. Terminel, Carla Bassil, Josephina Rau, Amanda Trevino, Cristina Ruiz, Robert Alaniz and Michelle A. Hook
    Citation: BMC Neuroscience 2022 23:58
  13. Auditory steady-state responses (ASSRs) are periodic evoked responses to constant periodic auditory stimuli, such as click trains, and are suggested to be associated with higher cognitive functions in humans. ...

    Authors: Tomoya Nakamura, Trong Ha Dinh, Makoto Asai, Hiroshi Nishimaru, Jumpei Matsumoto, Tsuyoshi Setogawa, Hiroyuki Ichijo, Sokichi Honda, Hiroshi Yamada, Takuma Mihara and Hisao Nishijo
    Citation: BMC Neuroscience 2022 23:57
  14. Dysregulation of long noncoding RNA (lncRNA) expression is related to aging and age-associated neurodegenerative diseases, and the lncRNA expression profile in the aging hippocampus is not well characterized. ...

    Authors: Li Qi, Xiao Li, Shi-min Liu, Dan-li Jiao, Dan Hu, Xin-yao Ju, Shu-yu Zhao, Shu-han Si, Li Hu, Guo-na Li, Bing-zhe Ma, Shuang Zhou and Chen Zhao
    Citation: BMC Neuroscience 2022 23:56
  15. Neuronal injury induced in young rats by cerebral ischemia reperfusion (CIR) is known to differ substantially from that in adult rats. In the present study, we investigated the specific differences in neuronal...

    Authors: Jie Wang, Zihao Xia, Peng Sheng, Mengmeng Shen, Lidong Ding, Dezhi Liu and Bing Chun Yan
    Citation: BMC Neuroscience 2022 23:55
  16. Exercise boosts the health of some brain parts, such as the hippocampus and hypothalamus. Several studies show that long-term exercise improves spatial learning and memory, enhances hypothalamic leptin sensiti...

    Authors: Shu-Jing Liu, Tong-Hui Cai, Chun-Lu Fang, Shao-Zhang Lin, Wen-Qi Yang, Yuan Wei, Fu Zhou, Ling Liu, Yuan Luo, Zi-Yi Guo, Ge Zhao, Ya-Ping Li and Liang-Ming Li
    Citation: BMC Neuroscience 2022 23:54
  17. Glioblastoma (GBM) is an aggressive and malignant brain tumor with extremely poor prognosis. Despite advances in treatment, the pathogenesis of GBM remains elusive. Mounting studies have revealed the critical ...

    Authors: Qingjiu Zhou, Mahati Shaya, Yalikun Kugeluke, Qiang Fu, Shaoshan Li and Yisireyili Dilimulati
    Citation: BMC Neuroscience 2022 23:53
  18. Paraoxonase 2 (PON2) is an intracellular antioxidant enzyme located at the inner mitochondrial membrane. Previous studies have found PON2 to be an important antioxidant in a variety of cellular systems, such a...

    Authors: Jacqueline M. Garrick, Khoi Dao, Lucio G. Costa, Judit Marsillach and Clement E. Furlong
    Citation: BMC Neuroscience 2022 23:52
  19. Spinal cord injury (SCI) is a common trauma in clinical practices. Subacute SCI is mainly characterized by neuronal apoptosis, axonal demyelination, Wallerian degeneration, axonal remodeling, and glial scar fo...

    Authors: Lei Yan, Jiawei Fu, Xiong Dong, Baishen Chen, Hongxiang Hong and Zhiming Cui
    Citation: BMC Neuroscience 2022 23:51
  20. Evidences indicate that inflammasome compounds participate in amyotrophic lateral sclerosis (ALS), a fatal progressive motoneuron degenerative disease. Researchers have observed the expressions of nucleotide o...

    Authors: Haoyun Zhang, Hao Li, Bingkun Huang, Shaoye Wang, Ying Gao, Fandi Meng, Yanchun Chen, Fenghua Zhou, Yingjun Guan and Xin Wang
    Citation: BMC Neuroscience 2022 23:50
  21. Microglia assume opposite phenotypes in response to ischemic brain injury, exerting neurotoxic and neuroprotective effects under different ischemic stages. Modulating M1/M2 polarization is a potential therapy ...

    Authors: Ye Hong, Jinfeng Lyu, Lin Zhu, Xixi Wang, Mengna Peng, Xiangliang Chen, Qiwen Deng, Jie Gao, Zhenhua Yuan, Di Wang, Gelin Xu and Mengyi Xu
    Citation: BMC Neuroscience 2022 23:49
  22. During neurodegenerative diseases, the brain undergoes morphological and pathological changes; Iron deposits are one of the causes of pathological changes in the brain. The Quantitative susceptibility mapping ...

    Authors: Farzaneh Nikparast, Zohreh Ganji and Hoda Zare
    Citation: BMC Neuroscience 2022 23:48
  23. Stem cell-based therapy has received considerable attention as a potential candidate in the treatment of ischemic stroke; however, employing an appropriate type of stem cells and an effective delivery route ar...

    Authors: Seyedeh Maryam Mousavi, Bijan Akbarpour, Saeideh Karimi-Haghighi, Sareh Pandamooz, Ivaldo Jesus Almeida Belém-Filho, Marianella Masís-Calvo, Haniye Salimi, Ramin Lashanizadegan, Alireza Pouramini, Maryam Owjfard, Etrat Hooshmandi, Mahnaz Bayat, Seyedeh Shaghayegh Zafarmand, Mehdi Dianatpour, Mohammad Saied Salehi and Afshin Borhani-Haghighi
    Citation: BMC Neuroscience 2022 23:47
  24. Following one mild traumatic brain injury (mTBI), there is a window of vulnerability during which subsequent mTBIs can cause substantially exacerbated impairments. Currently, there are no known methods to moni...

    Authors: Prashanth S. Velayudhan, Jordan J. Mak, Lisa M. Gazdzinski and Anne L. Wheeler
    Citation: BMC Neuroscience 2022 23:46
  25. Physical exercise and neurorehabilitation involve repetitive training that can induce changes in motor performance arising from neuroplasticity. Retention of these motor changes occurs via an encoding process,...

    Authors: Martin V. Sale and Anastasiia Kuzovina
    Citation: BMC Neuroscience 2022 23:45
  26. Following Spinal Cord Injury (SCI), innumerable inflammatory and degenerative fluctuations appear in the injured site, and even remotely in manifold areas of the brain. Howbeit, inflammatory, degenerative, and...

    Authors: Ahad Karimzadeh Kalkhoran, Mohammad Reza Alipour, Mohsen Jafarzadehgharehziaaddin, Hamid Soltani Zangbar and Parviz Shahabi
    Citation: BMC Neuroscience 2022 23:44
  27. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly contagious, and the neurological symptoms of SARS-CoV-2 infection have already been reported. However, the mechanisms underlying the effec...

    Authors: Rui-Cheng Yang, Kun Huang, Hui-Peng Zhang, Liang Li, Chen Tan, Huan-Chun Chen, Mei-Lin Jin and Xiang-Ru Wang
    Citation: BMC Neuroscience 2022 23:43
  28. Cervical spondylotic myelopathy (CSM) is a clinically symptomatic condition due to spinal cord compression, leading to spinal cord dysfunction. Surgical decompression is the main treatment of CSM, but the mech...

    Authors: Peisheng Liu, Xiaofeng Li, Jing Liu, Hengjia Zhang, Zhitao You and Jianfeng Zhang
    Citation: BMC Neuroscience 2022 23:42
  29. Exercise could prevent physical and psychological deteriorations, especially during pandemic times of lock-down scenarios and social isolation. But to meet both, the common exercise protocols require optimizat...

    Authors: V. Abeln, E. Fomina, J. Popova, L. Braunsmann, J. Koschate, F. Möller, S. O. Fedyay, G. Y. Vassilieva, S. Schneider, H. K. Strüder and T. Klein
    Citation: BMC Neuroscience 2022 23:41
  30. Corticotropin-releasing factor (CRF) is the major neuromodulator orchestrating the stress response, and is secreted by neurons in various regions of the brain. Cerebellar CRF is released by afferents from infe...

    Authors: Guang-Gao Li, Chun-Jian Piao, Peng Wan, Shu-Yu Li, Yu-Xuan Wei, Guo-Jun Zhao, Wen-Yuan Wu, Lan Hong, Chun-Ping Chu and De-Lai Qiu
    Citation: BMC Neuroscience 2022 23:39
  31. Critical development period of intestinal microbiota occurs concurrently with brain development, and their interaction is influenced by the microbiota–gut–brain axis. This study examined how antibiotics exposu...

    Authors: Yujie Zhang, Huijing Liang, Yimie Wang, Ruyue Cheng, Fangfang Pu, Yang Yang, Jinxing Li, Simou Wu, Xi Shen and Fang He
    Citation: BMC Neuroscience 2022 23:38
  32. Autologous vein wrapping (VW) is used in the treatment of recurrent chronic constriction neuropathy and traumatic peripheral nerve injury. However, use of autologous veins is limited by the inability to obtain...

    Authors: Michiaki Mukai, Kentaro Uchida, Naoya Hirosawa, Kenichi Murakami, Gen Inoue, Masayuki Miyagi, Yasuhiro Shiga, Hiroyuki Sekiguchi, Kazuhide Inage, Sumihisa Orita, Takane Suzuki, Yusuke Matsuura, Masashi Takaso and Seiji Ohtori
    Citation: BMC Neuroscience 2022 23:37
  33. To examine the pathological effect of a mesial temporal seizure onset zone (SOZ) on local and inter-regional response to faces in the amygdala and other structures of the temporal lobe.

    Authors: Ji-Won Kim, Katja E. Brückner, Celina Badenius, Wolfgang Hamel, Miriam Schaper, Michel Le Van Quyen, Elisa K. El-Allawy-Zielke, Stefan R. G. Stodieck, Jonas M. Hebel and Michael Lanz
    Citation: BMC Neuroscience 2022 23:36
  34. Temporal envelope cues are conveyed by cochlear implants (CIs) to hearing loss patients to restore hearing. Although CIs could enable users to communicate in clear listening environments, noisy environments st...

    Authors: Yang Guo, Zhong Zheng, Keyi Li, Yuanyuan Sun, Liang Xia, Di Qian and Yanmei Feng
    Citation: BMC Neuroscience 2022 23:35
  35. Natural nutrition and physical training have been defined as non-pharmacochemical complementary and alternative medicines to prevent and treat various pathogenesis. Royal jelly possesses various pharmacologica...

    Authors: Maryam Lohrasbi, Farzaneh Taghian, Khosro Jalali Dehkordi and Seyed Ali Hosseini
    Citation: BMC Neuroscience 2022 23:34
  36. Fragile X syndrome, the major cause of inherited intellectual disability among men, is due to deficiency of the synaptic functional regulator FMR1 protein (FMRP), encoded by the FMRP translational regulator 1 (FM...

    Authors: Juliana C. Corrêa-Velloso, Alessandra M. Linardi, Talita Glaser, Fernando J. Velloso, Maria P. Rivas, Renata E P. Leite, Lea T. Grinberg, Henning Ulrich, Michael R. Akins, Silvana Chiavegatto and Luciana A. Haddad
    Citation: BMC Neuroscience 2022 23:32
  37. Therapeutic agents stimulating the process of myelination could be beneficial for the treatment of demyelinating diseases, such as multiple sclerosis. The efficient translation of compounds promoting myelinati...

    Authors: Karen Lariosa-Willingham, Dmitri Leonoudakis, Timo Bragge, Laura Tolppanen, Antti Nurmi, Megan Flanagan, Janelle Gibson, David Wilson, Jennifer Stratton, Kimmo K. Lehtimäki and Diana Miszczuk
    Citation: BMC Neuroscience 2022 23:30
  38. The kaolin induced obstructive hydrocephalus (OHC) model is well known for its ability to increase intracranial pressure (ICP) in experimental animals. Papilledema (PE) which is a predominant hallmark of eleva...

    Authors: Snorre Malm Hagen, Sajedeh Eftekhari, Steffen Hamann, Marianne Juhler and Rigmor H. Jensen
    Citation: BMC Neuroscience 2022 23:29
  39. Psychological disorders including depression, anxiety, and stress comprise a huge public health problem. The aim of this cross-sectional study is to assess the relationship between dietary glycemic index (DGI)...

    Authors: Ali Amirinejad, Mina Darand, Ian G. Davies, Mohsen Mazidi, Azadeh Nadjarzadeh, Masoud Mirzaei and Sayyed Saeid Khayyatzadeh
    Citation: BMC Neuroscience 2022 23:28
  40. Transcranial magneto-acoustical stimulation (TMAS) is a noninvasive technique that has advantages in spatial resolution and penetration depth. It changes the firing properties of neurons through the current ge...

    Authors: Song Zhao, Dan Liu, Minzhuang Liu, Xiaoyuan Luo and Yi Yuan
    Citation: BMC Neuroscience 2022 23:26
  41. Hashimoto’s thyroiditis (HT) is an autoimmune illness that renders individuals vulnerable to neuropsychopathology even in the euthyroid state, the mechanisms involved remain unclear. We hypothesized that activ...

    Authors: Fen Wang, Yao-Jun Cai, Xiao Ma, Nan Wang, Zhang-Bi Wu, Yan Sun, Yong-xia Xu, Hao Yang, Tian-tian Liu, Qin Xia, Zhen Yu and De-Fa Zhu
    Citation: BMC Neuroscience 2022 23:25
  42. visual expertise and experience modulate evoked brain activity in response to training-related stimuli. However, few studies have considered how the visual experience is represented in the resting state brain ...

    Authors: Ting Zhang, Minghao Dong, Hongmei Wang, Rui Jia, Fu Li, Xiaoli Ni and Chenwang Jin
    Citation: BMC Neuroscience 2022 23:24
  43. Some degree of spontaneous recovery is usually observed after stroke. Experimental studies have provided information about molecular mechanisms underlying this recovery. However, the majority of pre-clinical s...

    Authors: Maryam Mostajeran, Lars Edvinsson, Hilda Ahnstedt, Kajsa Arkelius and Saema Ansar
    Citation: BMC Neuroscience 2022 23:23
  44. The preventive role of muscular strength on diminishing neuroinflammation is yet unknown. In this study, the role of the prophylactic muscular strength exercise was investigated in order to verify whether it w...

    Authors: Elizama de Gregório, Gabriela Cristiane Mendes, Lincon Bordignon Somensi, Cassio Geremia Freire, Luiza Freitas Lopes, Karine Ramires Lima, Guilherme Salgado Carrazoni, Ben-Hur Souto Neves, Steffanie Severo Picua, Luisa Mota da Silva, Pamela Billig Mello-Carpes, Juliana Sartori Bonini and Weber Claudio da Silva
    Citation: BMC Neuroscience 2022 23:22

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