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  1. Neuronal injury induced in young rats by cerebral ischemia reperfusion (CIR) is known to differ substantially from that in adult rats. In the present study, we investigated the specific differences in neuronal...

    Authors: Jie Wang, Zihao Xia, Peng Sheng, Mengmeng Shen, Lidong Ding, Dezhi Liu and Bing Chun Yan
    Citation: BMC Neuroscience 2022 23:55
    Content type: Research Published on:

  2. Exercise boosts the health of some brain parts, such as the hippocampus and hypothalamus. Several studies show that long-term exercise improves spatial learning and memory, enhances hypothalamic leptin sensiti...

    Authors: Shu-Jing Liu, Tong-Hui Cai, Chun-Lu Fang, Shao-Zhang Lin, Wen-Qi Yang, Yuan Wei, Fu Zhou, Ling Liu, Yuan Luo, Zi-Yi Guo, Ge Zhao, Ya-Ping Li and Liang-Ming Li
    Citation: BMC Neuroscience 2022 23:54
    Content type: Research Published on:

  3. Glioblastoma (GBM) is an aggressive and malignant brain tumor with extremely poor prognosis. Despite advances in treatment, the pathogenesis of GBM remains elusive. Mounting studies have revealed the critical ...

    Authors: Qingjiu Zhou, Mahati Shaya, Yalikun Kugeluke, Qiang Fu, Shaoshan Li and Yisireyili Dilimulati
    Citation: BMC Neuroscience 2022 23:53
    Content type: Research Published on:

  4. Paraoxonase 2 (PON2) is an intracellular antioxidant enzyme located at the inner mitochondrial membrane. Previous studies have found PON2 to be an important antioxidant in a variety of cellular systems, such a...

    Authors: Jacqueline M. Garrick, Khoi Dao, Lucio G. Costa, Judit Marsillach and Clement E. Furlong
    Citation: BMC Neuroscience 2022 23:52
    Content type: Research Published on:

  5. Spinal cord injury (SCI) is a common trauma in clinical practices. Subacute SCI is mainly characterized by neuronal apoptosis, axonal demyelination, Wallerian degeneration, axonal remodeling, and glial scar fo...

    Authors: Lei Yan, Jiawei Fu, Xiong Dong, Baishen Chen, Hongxiang Hong and Zhiming Cui
    Citation: BMC Neuroscience 2022 23:51
    Content type: Research Published on:

  6. Evidences indicate that inflammasome compounds participate in amyotrophic lateral sclerosis (ALS), a fatal progressive motoneuron degenerative disease. Researchers have observed the expressions of nucleotide o...

    Authors: Haoyun Zhang, Hao Li, Bingkun Huang, Shaoye Wang, Ying Gao, Fandi Meng, Yanchun Chen, Fenghua Zhou, Yingjun Guan and Xin Wang
    Citation: BMC Neuroscience 2022 23:50
    Content type: Research Published on:

  7. Microglia assume opposite phenotypes in response to ischemic brain injury, exerting neurotoxic and neuroprotective effects under different ischemic stages. Modulating M1/M2 polarization is a potential therapy ...

    Authors: Ye Hong, Jinfeng Lyu, Lin Zhu, Xixi Wang, Mengna Peng, Xiangliang Chen, Qiwen Deng, Jie Gao, Zhenhua Yuan, Di Wang, Gelin Xu and Mengyi Xu
    Citation: BMC Neuroscience 2022 23:49
    Content type: Research Published on:

  8. During neurodegenerative diseases, the brain undergoes morphological and pathological changes; Iron deposits are one of the causes of pathological changes in the brain. The Quantitative susceptibility mapping ...

    Authors: Farzaneh Nikparast, Zohreh Ganji and Hoda Zare
    Citation: BMC Neuroscience 2022 23:48
    Content type: Research Published on:

  9. Stem cell-based therapy has received considerable attention as a potential candidate in the treatment of ischemic stroke; however, employing an appropriate type of stem cells and an effective delivery route ar...

    Authors: Seyedeh Maryam Mousavi, Bijan Akbarpour, Saeideh Karimi-Haghighi, Sareh Pandamooz, Ivaldo Jesus Almeida Belém-Filho, Marianella Masís-Calvo, Haniye Salimi, Ramin Lashanizadegan, Alireza Pouramini, Maryam Owjfard, Etrat Hooshmandi, Mahnaz Bayat, Seyedeh Shaghayegh Zafarmand, Mehdi Dianatpour, Mohammad Saied Salehi and Afshin Borhani-Haghighi
    Citation: BMC Neuroscience 2022 23:47
    Content type: Research Published on:

  10. Following one mild traumatic brain injury (mTBI), there is a window of vulnerability during which subsequent mTBIs can cause substantially exacerbated impairments. Currently, there are no known methods to moni...

    Authors: Prashanth S. Velayudhan, Jordan J. Mak, Lisa M. Gazdzinski and Anne L. Wheeler
    Citation: BMC Neuroscience 2022 23:46
    Content type: Research article Published on:

  11. Physical exercise and neurorehabilitation involve repetitive training that can induce changes in motor performance arising from neuroplasticity. Retention of these motor changes occurs via an encoding process,...

    Authors: Martin V. Sale and Anastasiia Kuzovina
    Citation: BMC Neuroscience 2022 23:45
    Content type: Research Published on:

  12. Following Spinal Cord Injury (SCI), innumerable inflammatory and degenerative fluctuations appear in the injured site, and even remotely in manifold areas of the brain. Howbeit, inflammatory, degenerative, and...

    Authors: Ahad Karimzadeh Kalkhoran, Mohammad Reza Alipour, Mohsen Jafarzadehgharehziaaddin, Hamid Soltani Zangbar and Parviz Shahabi
    Citation: BMC Neuroscience 2022 23:44
    Content type: Research Published on:

  13. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly contagious, and the neurological symptoms of SARS-CoV-2 infection have already been reported. However, the mechanisms underlying the effec...

    Authors: Rui-Cheng Yang, Kun Huang, Hui-Peng Zhang, Liang Li, Chen Tan, Huan-Chun Chen, Mei-Lin Jin and Xiang-Ru Wang
    Citation: BMC Neuroscience 2022 23:43
    Content type: Research Published on:

  14. Cervical spondylotic myelopathy (CSM) is a clinically symptomatic condition due to spinal cord compression, leading to spinal cord dysfunction. Surgical decompression is the main treatment of CSM, but the mech...

    Authors: Peisheng Liu, Xiaofeng Li, Jing Liu, Hengjia Zhang, Zhitao You and Jianfeng Zhang
    Citation: BMC Neuroscience 2022 23:42
    Content type: Research Published on:

  15. Exercise could prevent physical and psychological deteriorations, especially during pandemic times of lock-down scenarios and social isolation. But to meet both, the common exercise protocols require optimizat...

    Authors: V. Abeln, E. Fomina, J. Popova, L. Braunsmann, J. Koschate, F. Möller, S. O. Fedyay, G. Y. Vassilieva, S. Schneider, H. K. Strüder and T. Klein
    Citation: BMC Neuroscience 2022 23:41
    Content type: Research Published on:

  17. Corticotropin-releasing factor (CRF) is the major neuromodulator orchestrating the stress response, and is secreted by neurons in various regions of the brain. Cerebellar CRF is released by afferents from infe...

    Authors: Guang-Gao Li, Chun-Jian Piao, Peng Wan, Shu-Yu Li, Yu-Xuan Wei, Guo-Jun Zhao, Wen-Yuan Wu, Lan Hong, Chun-Ping Chu and De-Lai Qiu
    Citation: BMC Neuroscience 2022 23:39
    Content type: Research Published on:

  18. Critical development period of intestinal microbiota occurs concurrently with brain development, and their interaction is influenced by the microbiota–gut–brain axis. This study examined how antibiotics exposu...

    Authors: Yujie Zhang, Huijing Liang, Yimie Wang, Ruyue Cheng, Fangfang Pu, Yang Yang, Jinxing Li, Simou Wu, Xi Shen and Fang He
    Citation: BMC Neuroscience 2022 23:38
    Content type: Research Published on:

  19. Autologous vein wrapping (VW) is used in the treatment of recurrent chronic constriction neuropathy and traumatic peripheral nerve injury. However, use of autologous veins is limited by the inability to obtain...

    Authors: Michiaki Mukai, Kentaro Uchida, Naoya Hirosawa, Kenichi Murakami, Gen Inoue, Masayuki Miyagi, Yasuhiro Shiga, Hiroyuki Sekiguchi, Kazuhide Inage, Sumihisa Orita, Takane Suzuki, Yusuke Matsuura, Masashi Takaso and Seiji Ohtori
    Citation: BMC Neuroscience 2022 23:37
    Content type: Research Published on:

  20. To examine the pathological effect of a mesial temporal seizure onset zone (SOZ) on local and inter-regional response to faces in the amygdala and other structures of the temporal lobe.

    Authors: Ji-Won Kim, Katja E. Brückner, Celina Badenius, Wolfgang Hamel, Miriam Schaper, Michel Le Van Quyen, Elisa K. El-Allawy-Zielke, Stefan R. G. Stodieck, Jonas M. Hebel and Michael Lanz
    Citation: BMC Neuroscience 2022 23:36
    Content type: Research Published on:

  21. Temporal envelope cues are conveyed by cochlear implants (CIs) to hearing loss patients to restore hearing. Although CIs could enable users to communicate in clear listening environments, noisy environments st...

    Authors: Yang Guo, Zhong Zheng, Keyi Li, Yuanyuan Sun, Liang Xia, Di Qian and Yanmei Feng
    Citation: BMC Neuroscience 2022 23:35
    Content type: Research Published on:

  22. Natural nutrition and physical training have been defined as non-pharmacochemical complementary and alternative medicines to prevent and treat various pathogenesis. Royal jelly possesses various pharmacologica...

    Authors: Maryam Lohrasbi, Farzaneh Taghian, Khosro Jalali Dehkordi and Seyed Ali Hosseini
    Citation: BMC Neuroscience 2022 23:34
    Content type: Research Published on:

  24. Fragile X syndrome, the major cause of inherited intellectual disability among men, is due to deficiency of the synaptic functional regulator FMR1 protein (FMRP), encoded by the FMRP translational regulator 1 (FM...

    Authors: Juliana C. Corrêa-Velloso, Alessandra M. Linardi, Talita Glaser, Fernando J. Velloso, Maria P. Rivas, Renata E P. Leite, Lea T. Grinberg, Henning Ulrich, Michael R. Akins, Silvana Chiavegatto and Luciana A. Haddad
    Citation: BMC Neuroscience 2022 23:32
    Content type: Research article Published on:

  26. Therapeutic agents stimulating the process of myelination could be beneficial for the treatment of demyelinating diseases, such as multiple sclerosis. The efficient translation of compounds promoting myelinati...

    Authors: Karen Lariosa-Willingham, Dmitri Leonoudakis, Timo Bragge, Laura Tolppanen, Antti Nurmi, Megan Flanagan, Janelle Gibson, David Wilson, Jennifer Stratton, Kimmo K. Lehtimäki and Diana Miszczuk
    Citation: BMC Neuroscience 2022 23:30
    Content type: Research Published on:

  27. The kaolin induced obstructive hydrocephalus (OHC) model is well known for its ability to increase intracranial pressure (ICP) in experimental animals. Papilledema (PE) which is a predominant hallmark of eleva...

    Authors: Snorre Malm Hagen, Sajedeh Eftekhari, Steffen Hamann, Marianne Juhler and Rigmor H. Jensen
    Citation: BMC Neuroscience 2022 23:29
    Content type: Research Published on:

  28. Psychological disorders including depression, anxiety, and stress comprise a huge public health problem. The aim of this cross-sectional study is to assess the relationship between dietary glycemic index (DGI)...

    Authors: Ali Amirinejad, Mina Darand, Ian G. Davies, Mohsen Mazidi, Azadeh Nadjarzadeh, Masoud Mirzaei and Sayyed Saeid Khayyatzadeh
    Citation: BMC Neuroscience 2022 23:28
    Content type: Research Published on:

  30. Transcranial magneto-acoustical stimulation (TMAS) is a noninvasive technique that has advantages in spatial resolution and penetration depth. It changes the firing properties of neurons through the current ge...

    Authors: Song Zhao, Dan Liu, Minzhuang Liu, Xiaoyuan Luo and Yi Yuan
    Citation: BMC Neuroscience 2022 23:26
    Content type: Research article Published on:

  31. Hashimoto’s thyroiditis (HT) is an autoimmune illness that renders individuals vulnerable to neuropsychopathology even in the euthyroid state, the mechanisms involved remain unclear. We hypothesized that activ...

    Authors: Fen Wang, Yao-Jun Cai, Xiao Ma, Nan Wang, Zhang-Bi Wu, Yan Sun, Yong-xia Xu, Hao Yang, Tian-tian Liu, Qin Xia, Zhen Yu and De-Fa Zhu
    Citation: BMC Neuroscience 2022 23:25
    Content type: Research Published on:

  32. visual expertise and experience modulate evoked brain activity in response to training-related stimuli. However, few studies have considered how the visual experience is represented in the resting state brain ...

    Authors: Ting Zhang, Minghao Dong, Hongmei Wang, Rui Jia, Fu Li, Xiaoli Ni and Chenwang Jin
    Citation: BMC Neuroscience 2022 23:24
    Content type: Research article Published on:

  33. Some degree of spontaneous recovery is usually observed after stroke. Experimental studies have provided information about molecular mechanisms underlying this recovery. However, the majority of pre-clinical s...

    Authors: Maryam Mostajeran, Lars Edvinsson, Hilda Ahnstedt, Kajsa Arkelius and Saema Ansar
    Citation: BMC Neuroscience 2022 23:23
    Content type: Research article Published on:

  34. The preventive role of muscular strength on diminishing neuroinflammation is yet unknown. In this study, the role of the prophylactic muscular strength exercise was investigated in order to verify whether it w...

    Authors: Elizama de Gregório, Gabriela Cristiane Mendes, Lincon Bordignon Somensi, Cassio Geremia Freire, Luiza Freitas Lopes, Karine Ramires Lima, Guilherme Salgado Carrazoni, Ben-Hur Souto Neves, Steffanie Severo Picua, Luisa Mota da Silva, Pamela Billig Mello-Carpes, Juliana Sartori Bonini and Weber Claudio da Silva
    Citation: BMC Neuroscience 2022 23:22
    Content type: Research Published on:

  36. C-C motif chemokine ligand 2 (CCL2) is reported to be involved in the pathogenesis of various neurological and/or psychiatric diseases. Tissue or cellular expression of CCL2, in normal or pathological conditio...

    Authors: Xue Shi, Xinrui Gong, Huangui Xiong and Jingdong Zhang
    Citation: BMC Neuroscience 2022 23:20
    Content type: Research Published on:

  37. Deoxythymidine triphosphate (dTTP) is an essential building block of DNA, and defects in enzymes involved in dTTP synthesis cause neurodegenerative disorders. For instance, mutations in DTYMK, the gene coding for...

    Authors: Junmei Hu Frisk, Stefan Örn, Gunnar Pejler, Staffan Eriksson and Liya Wang
    Citation: BMC Neuroscience 2022 23:19
    Content type: Research article Published on:

  38. Hematoma expansion can be related to increased mortality and poor clinical outcomes in patients with intracerebral hemorrhage (ICH). So, early identification and prevention of hematoma expansion can be conside...

    Authors: Ehsan Alimohammadi, Seyed Reza Bagheri, Parand Mardanpour, Farid Moradi, Fatemeh Arjmandnia and Narges Esmaeili
    Citation: BMC Neuroscience 2022 23:18
    Content type: Research Published on:

  39. Cerebellar injury can not only cause gait and postural instability, nystagmus, and vertigo but also affect the vestibular system. However, changes in connectivity regarding the vestibular projection pathway af...

    Authors: Byeong Uk Gam, In Hee Cho, Sang Seok Yeo, Jung Won Kwon, Sung Ho Jang and Seunghue Oh
    Citation: BMC Neuroscience 2022 23:17
    Content type: Research Published on:

  41. Pituitary adenoma (PA) may compress the optic apparatus, resulting in impaired vision. Some patients can experience improved vision rapidly after surgery. During the early period after surgery, however, the ch...

    Authors: Fuyu Wang, Tao Zhou, Peng Wang, Ze Li, Xianghui Meng and Jinli Jiang
    Citation: BMC Neuroscience 2022 23:15
    Content type: Research article Published on:

  43. Neuroinflammation plays a prominent role in Alzheimer’s disease (AD), both in pathogenesis and disease progression. It has been shown that TLR/MYD88 signaling is involved in the chronic low-grade sterile infla...

    Authors: Catalina Anca Cucos, Maria Dobre, Elena Mihaela Dragnea, Gina Manda and Elena Milanesi
    Citation: BMC Neuroscience 2022 23:13
    Content type: Research Published on:

  44. Autism spectrum disorder (ASD) is characterized by repetitive behaviors, deficits in communication, and overall impaired social interaction. Of all the integrin subunit mutations, mutations in integrin β3 (Itgb3)...

    Authors: Andrew J. Lopuch, Brian D. Swinehart, Eden L. Widener, Z. Logan Holley, Katherine M. Bland, Christopher J. Handwerk, Cooper A. Brett, Hollyn N. Cook, Anna R. Kalinowski, Hilda V. Rodriguez, M. Irene Song and George S. Vidal
    Citation: BMC Neuroscience 2022 23:12
    Content type: Research article Published on:

  45. Mitoxantrone has proved efficacy in treatment of multiple sclerosis (MS). The fact that physical exercise could slow down the progression of disease and improve performance is still a debatable issue, hence; w...

    Authors: Mohamed A. El-Emam, Samar El Achy, Dalaal M. Abdallah, Hanan S. El-Abhar and Mennatallah A. Gowayed
    Citation: BMC Neuroscience 2022 23:11
    Content type: Research Published on:

  48. Retinoic acid-related orphan receptor alpha (RORA) has been reported to be suppressed in autistic patients and is associated with autism spectrum disorders (ASD), although the potential role and mechanism of R...

    Authors: Li Xiao, Min Wang, Wanhua Zhang, Yuan Song, Jiaying Zeng, Huilin Li, Hong Yu, Ling Li, Pingming Gao and Paul Yao
    Citation: BMC Neuroscience 2022 23:8
    Content type: Research Published on:

  49. The gut microbiota can modulate brain function and behavior and is increasingly recognized as an important factor in mediating the risk of epilepsy and the effects of seizure interventions. Drug therapy is one...

    Authors: Xiang Li, Qing Wang, Di Wu, Dian-wen Zhang, Shu-chang Li, Si-wei Zhang, Xia Chen and Wei Li
    Citation: BMC Neuroscience 2022 23:7
    Content type: Research Published on:

  50. In the horizon of therapeutic restrictions in intracerebral hemorrhage (ICH), recently, non-invasive transcranial electrical stimulation (tES) has achieved considerable prosperities. Translational studies have...

    Authors: Amir Reza Heidarzadegan, Asadollah Zarifkar, Narges Sotoudeh, Mohammad Reza Namavar and Amir Hossein Zarifkar
    Citation: BMC Neuroscience 2022 23:6
    Content type: Research Published on:
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BMC Neuroscience

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