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BMC Neuroscience

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  1. Content type: Research article

    Ischemic stroke is a major disease that threatens human health in ageing population. Increasing evidence has shown that neuroinflammatory mediators play crucial roles in the pathophysiology of cerebral ischemi...

    Authors: Wen-Xin Zeng, Yong-Li Han, Gao-Feng Zhu, Lin-Qiang Huang, Yi-Yu Deng, Qiao-Sheng Wang, Wen-Qiang Jiang, Miao-Yun Wen, Qian-Peng Han, Di Xie and Hong-Ke Zeng

    Citation: BMC Neuroscience 2017 18:32

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  2. Content type: Research article

    Increased motor activity or social interactions through enriched environment are strong stimulators of grey and white matter plasticity in the adult rodent brain. In the present study we evaluated whether spe...

    Authors: Silke Keiner, Fanny Niv, Susanne Neumann, Tanja Steinbach, Christian Schmeer, Katrin Hornung, Yvonne Schlenker, Martin Förster, Otto W. Witte and Christoph Redecker

    Citation: BMC Neuroscience 2017 18:31

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  3. Content type: Research article

    The possibility of using deep brain stimulation (DBS) for memory enhancement has recently been reported, but the precise underlying mechanisms of its effects remain unknown. Our previous study suggested that s...

    Authors: Da Un Jeong, Jihyeon Lee, Won Seok Chang and Jin Woo Chang

    Citation: BMC Neuroscience 2017 18:29

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  4. Content type: Research article

    Wallerian degeneration (WD) in injured peripheral nerves is associated with a large number of up- or down-regulated genes, but the effects of these changes are poorly understood. In our previous studies, we re...

    Authors: Xingyu Liu, Yuhua Sun, Huaiqin Li, Yuting Li, Meiyuan Li, Ying Yuan, Shusen Cui and Dengbing Yao

    Citation: BMC Neuroscience 2017 18:30

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  5. Content type: Research article

    EEG studies investigating the neural networks that facilitate action observation (AO) and kinaesthetic motor imagery (KMI) have shown reduced, or desynchronized, power in the alpha (8–12 Hz) and beta (13–30 Hz...

    Authors: Paula M. Di Nota, Julie M. Chartrand, Gabriella R. Levkov, Rodrigo Montefusco-Siegmund and Joseph F. X. DeSouza

    Citation: BMC Neuroscience 2017 18:28

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  6. Content type: Research article

    Primary open angle glaucoma is a heterogeneous group of optic neuropathies that results in optic nerve degeneration and a loss of retinal ganglion cells (RGCs) ultimately causing blindness if allowed to progre...

    Authors: Nolan R. McGrady, Alena Z. Minton, Dorota L. Stankowska, Shaoqing He, Hayden B. Jefferies and Raghu R. Krishnamoorthy

    Citation: BMC Neuroscience 2017 18:27

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  7. Content type: Research article

    The study investigates oscillatory brain activity during working memory (WM) tasks. The tasks employed varied in two dimensions. First, they differed in complexity from average to highly demanding. Second, we ...

    Authors: Yuri G. Pavlov and Boris Kotchoubey

    Citation: BMC Neuroscience 2017 18:26

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  8. Content type: Research article

    The role of the piriform cortex (PC) in olfactory information processing remains largely unknown. The anterior part of the piriform cortex (APC) has been the focus of cortical-level studies of olfactory codin...

    Authors: Junli Yang, Gerhard Litscher, Zhongren Sun, Qiang Tang, Kiyoshi Kishi, Satoko Oda, Masaaki Takayanagi, Zemin Sheng, Yang Liu, Wenhai Guo, Ting Zhang, Lu Wang, Ingrid Gaischek, Daniela Litscher, Irmgard Th. Lippe and Masaru Kuroda

    Citation: BMC Neuroscience 2017 18:25

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  9. Content type: Research article

    Synucleinopathies such as Parkinson’s disease or multiple system atrophy are characterized by Lewy bodies in distinct brain areas. These aggregates are mainly formed by α-synuclein inclusions, a protein crucia...

    Authors: R. Rabl, C. Breitschaedel, S. Flunkert, S. Duller, D. Amschl, J. Neddens, V. Niederkofler, E. Rockenstein, E. Masliah, H. Roemer and B. Hutter-Paier

    Citation: BMC Neuroscience 2017 18:22

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  10. Content type: Methodology

    Cation-chloride cotransporters (CCCs) are indispensable for maintaining chloride homeostasis in multiple cell types, but K–Cl cotransporter KCC2 is the only CCC member with an exclusively neuronal expression i...

    Authors: Anastasia Ludwig, Claudio Rivera and Pavel Uvarov

    Citation: BMC Neuroscience 2017 18:23

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  11. Content type: Research article

    TDP-43 aggregates accumulate in individuals affected by amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases, representing potential diagnostic and therapeutic targets. Using an atomic forc...

    Authors: Stephanie M. Williams, Galam Khan, Brent T. Harris, John Ravits and Michael R. Sierks

    Citation: BMC Neuroscience 2017 18:20

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  12. Content type: Research article

    Previous studies compared evoked potentials (EPs) between several sleep stages but only one uniform wake state. However, using electroencephalography (EEG), several arousal states can be distinguished before s...

    Authors: Jue Huang, Tilman Hensch, Christine Ulke, Christian Sander, Janek Spada, Philippe Jawinski and Ulrich Hegerl

    Citation: BMC Neuroscience 2017 18:21

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  13. Content type: Research Article

    There is a large body of experimental evidence suggesting that omega-3 (n-3) polyunsaturated fatty acids (PUFAs) are capable of modulating immune function. Some studies have shown that these PUFAs might have ...

    Authors: Elise Siegert, Friedemann Paul, Michael Rothe and Karsten H. Weylandt

    Citation: BMC Neuroscience 2017 18:19

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  14. Content type: methodology article

    Bioluminescence imaging (BLI) is a powerful technique for monitoring the temporal and spatial dynamics of gene expression in the mouse brain. However, the black fur, skin pigmentation and hair regrowth after d...

    Authors: Hironori Izumi, Tetsuya Ishimoto, Hiroshi Yamamoto and Hisashi Mori

    Citation: BMC Neuroscience 2017 18:18

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  15. Content type: Research article

    Previous studies have indicated that selenium supplementation may be beneficial in neuroprotection against glutamate-induced cell damage, in which mitochondrial dysfunction is considered a major pathogenic fea...

    Authors: Yan-Mei Ma, Gordon Ibeanu, Li-Yao Wang, Jian-Zhong Zhang, Yue Chang, Jian-Da Dong, P. Andy Li and Li Jing

    Citation: BMC Neuroscience 2017 18:15

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  16. Content type: Research Article

    Poly(ADP-ribose) polymerase 1 (PARP-1), which catalyzes poly(ADP-ribosyl)ation of proteins by using NAD+ as a substrate, plays a key role in several nuclear events, including DNA repair, replication, and transcri...

    Authors: Akiko Okuda, Suguru Kurokawa, Masanori Takehashi, Aika Maeda, Katsuya Fukuda, Yukari Kubo, Hyuma Nogusa, Tomoka Takatani-Nakase, Shujiro Okuda, Kunihiro Ueda and Seigo Tanaka

    Citation: BMC Neuroscience 2017 18:14

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  17. Content type: Research article

    Magnetic resonance spectroscopy (MRS) provides non-invasive information about the metabolic pattern of the brain parenchyma in vivo. The SpectraClassifier software performs MRS pattern-recognition by determin...

    Authors: Elena Jiménez-Xarrié, Myriam Davila, Ana Paula Candiota, Raquel Delgado-Mederos, Sandra Ortega-Martorell, Margarida Julià-Sapé, Carles Arús and Joan Martí-Fàbregas

    Citation: BMC Neuroscience 2017 18:13

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  18. Content type: Research article

    Deposition of aggregated amyloid beta (Aβ) protein is hallmark of Alzheimer’s disease, leading to dysfunction and apoptosis of neurons. The isoflavone phytoestrogen compound genistein (Gen) exerts a significan...

    Authors: Fuling You, Qiao Li, Guifang Jin, Yaojie Zheng, Jingrong Chen and Hong Yang

    Citation: BMC Neuroscience 2017 18:12

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  19. Content type: Research Article

    The fractalkine/CX3C chemokine receptor 1 (CX3CR1) pathway has been identified to play an essential role in the chemotaxis of microglia, leukocyte trafficking and microglia/macrophage recruitment. It has also bee...

    Authors: Gerlinde van der Maten, Vivien Henck, Tadeusz Wieloch and Karsten Ruscher

    Citation: BMC Neuroscience 2017 18:11

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  20. Content type: Research article

    Previous neuroimaging studies have shown the hemodynamic effect of either preconditioning or postconditioning anesthesia in ischemic stroke model. However, the anesthetic effect in hemodynamics during and imm...

    Authors: Hongyang Lu, Yao Li, Bin Bo, Lu Yuan, Xiaodan Lu, Hangdao Li and Shanbao Tong

    Citation: BMC Neuroscience 2017 18:10

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  21. Content type: Research article

    Ultraviolet B irradiation confers strong resistance against experimental autoimmune encephalomyelitis, a model of multiple sclerosis. This protection by ultraviolet B is independent of vitamin D production but...

    Authors: Amy A. Irving, Steven J. Marling, Lori A. Plum and Hector F. DeLuca

    Citation: BMC Neuroscience 2017 18:8

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