Articles
Page 5 of 98
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Citation: BMC Neuroscience 2021 22:64
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Hypothetical molecular interconnection between type 2 diabetes and dyslexia
Dyslexia is one of the most common learning disabilities, especially among children. Type 2 diabetes is a metabolic disorder that affects a large population globally, with metabolic disorders. There have been ...
Citation: BMC Neuroscience 2021 22:63 -
Cerebral ventriculomegaly in myotonic dystrophy type 1: normal pressure hydrocephalus-like appearances on magnetic resonance imaging
Cerebral ventriculomegaly is an abnormal feature characteristic of myotonic dystrophy type 1 (DM1). This retrospective study investigated the morphologic changes accompanied by ventriculomegaly in DM1 on brain...
Citation: BMC Neuroscience 2021 22:62 -
Electrical stimulation of the common peroneal nerve and its effects on the relationship between corticomuscular coherence and motor control in healthy adults
Sensory input via neuromuscular electrical stimulation (NMES) may contribute to synchronization between motor cortex and spinal motor neurons and motor performance improvement in healthy adults and stroke pati...
Citation: BMC Neuroscience 2021 22:61 -
A systematic review of common genetic variation and biological pathways in autism spectrum disorder
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by persistent deficits in social communication and interaction. Common genetic variation appears to play a key role in the...
Citation: BMC Neuroscience 2021 22:60 -
The neurodevelopmental basis of schizophrenia: clinical clues from craniofacial dysmorphology in northwest Ethiopia, 2020
The neurodevelopmental speculation of schizophrenia states that the pathogenesis of schizophrenia starts with early fetal or neonatal neurocraniofacial development rather than youthful adulthood when manic sig...
Citation: BMC Neuroscience 2021 22:59 -
Publisher Correction to: Uptake of Aβ by OATPs might be a new pathophysiological mechanism of Alzheimer disease
Citation: BMC Neuroscience 2021 22:58 -
The functional indexes of RBCs and microcirculation in the traumatic brain injury with the action of 2-ethil-6-methil-3-hydroxypiridin succinate
To study the RBCs functional and metabolic parameters and the microcirculatory brain structure at traumatic brain injury (TBI) under the action of 2-ethyl-6-methyl-3-hydroxypyridine succinate.
Citation: BMC Neuroscience 2021 22:57 -
NRXN1α+/- is associated with increased excitability in ASD iPSC-derived neurons
NRXN1 deletions are identified as one of major rare risk factors for autism spectrum disorder (ASD) and other neurodevelopmental disorders. ASD has 30% co-morbidity with epilepsy, and the latter is associated wit...
Citation: BMC Neuroscience 2021 22:56 -
Evaluating a new verbal working memory-balance program: a double-blind, randomized controlled trial study on Iranian children with dyslexia
It is important to improve verbal Working Memory (WM) in reading disability, as it is a key factor in learning. There are commercial verbal WM training programs, which have some short-term effects only on the ...
Citation: BMC Neuroscience 2021 22:55 -
Ceftriaxone therapy attenuates brain trauma in rats by affecting glutamate transporters and neuroinflammation and not by its antibacterial effects
Ceftriaxone is a β-lactam antibiotic used to treat central nervous system infections. Whether the neuroprotective effects of ceftriaxone after TBI are mediated by attenuating neuroinflammation but not its anti...
Citation: BMC Neuroscience 2021 22:54 -
Uptake of Aβ by OATPs might be a new pathophysiological mechanism of Alzheimer disease
The accumulation of neurotoxic amyloid-beta (Aβ) in the brain is a characteristic of Alzheimer's disease (AD), at the same time, it is possible alterations of liver function could affect brain Aβ levels throug...
Citation: BMC Neuroscience 2021 22:53 -
Effect of extremely low frequency magnetic fields on oxidative balance in rat brains subjected to an experimental model of chronic unpredictable mild stress
There has been an increasing interest in researching on the effects of extremely low-frequency magnetic fields on living systems. The mechanism of action of extremely low-frequency magnetic fields on organisms...
Citation: BMC Neuroscience 2021 22:52 -
Brain multimodal co-alterations related to delay discounting: a multimodal MRI fusion analysis in persons with and without cocaine use disorder
Delay discounting has been proposed as a behavioral marker of substance use disorders. Innovative analytic approaches that integrate information from multiple neuroimaging modalities can provide new insights i...
Citation: BMC Neuroscience 2021 22:51 -
Differential effects of rat ADSCs encapsulation in fibrin matrix and combination delivery of BDNF and Gold nanoparticles on peripheral nerve regeneration
Fibrin as an extracellular matrix feature like biocompatibility, creates a favorable environment for proliferation and migration of cells and it can act as a reservoir for storage and release of growth factors...
Citation: BMC Neuroscience 2021 22:50 -
Five-year outcomes after IVIG for mild cognitive impairment due to alzheimer disease
The purpose of this study was to assess the five-year treatment effects of a short course of intravenous immunoglobulin (IVIG) in subjects with mild cognitive impairment (MCI) due to Alzheimer disease (AD).
Citation: BMC Neuroscience 2021 22:49 -
Stressor controllability modulates the stress response in fish
In humans the stress response is known to be modulated to a great extent by psychological factors, particularly by the predictability and the perceived control that the subject has of the stressor. This psycho...
Citation: BMC Neuroscience 2021 22:48 -
The disrupted topological properties of structural networks showed recovery in ischemic stroke patients: a longitudinal design study
Stroke is one of the leading causes of substantial disability worldwide. Previous studies have shown brain functional and structural alterations in adults with stroke. However, few studies have examined the lo...
Citation: BMC Neuroscience 2021 22:47 -
Epileptiform activity in mouse hippocampal slices induced by moderate changes in extracellular Mg2+, Ca2+, and K+
Rodent brain slices—particularly hippocampal slices—are widely used in experimental investigations of epileptiform activity. Oxygenated artificial cerebrospinal fluid (ACSF) is used to maintain slices in vitro...
Citation: BMC Neuroscience 2021 22:46 -
In vivo oxygen measurement in cerebrospinal fluid of pigs to determine physiologic and pathophysiologic oxygen values during CNS infections
During infection and inflammation, a reduced oxygen level clearly affects cellular functions. Oxygen levels during CNS infections are unknown. Here we established and evaluated an in vivo measurement system to...
Citation: BMC Neuroscience 2021 22:45 -
The neuroprotective effects of AMN082 on neuronal apoptosis in rats after traumatic brain injury
The aim of this study was to investigate whether AMN082 exerts its neuroprotective effect by attenuating glutamate receptor-associated neuronal apoptosis and improving functional outcomes after traumatic brain...
Citation: BMC Neuroscience 2021 22:44 -
Phenotypic overlap between atopic dermatitis and autism
Autism, a childhood behavioral disorder, belongs to a large suite of diseases, collectively referred to as autism spectrum disorders (ASD). Though multifactorial in etiology, approximately 10% of ASD are assoc...
Citation: BMC Neuroscience 2021 22:43 -
Brain size reductions associated with endothelin B receptor mutation, a cause of Hirschsprung’s disease
ETB has been reported to regulate neurogenesis and vasoregulation in foetal development. Its dysfunction was known to cause HSCR, an aganglionic colonic disorder with syndromic forms reported to associate with bo...
Citation: BMC Neuroscience 2021 22:42 -
Memantine ameliorates cognitive deficit in AD mice via enhancement of entorhinal–CA1 projection
Memantine, a low- to moderate-affinity uncompetitive N-methyl-D-aspartate receptor antagonist, has been shown to improve cognitive functions in animal models of Alzheimer’s disease (AD). Here we treated APP/PS...
Citation: BMC Neuroscience 2021 22:41 -
Retraction Note to: Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12868-021-00644-1
Citation: BMC Neuroscience 2021 22:40 -
MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer’s disease
Matrix metallopeptidase 9 (MMP9) has been implicated in a variety of neurological disorders, including Alzheimer’s disease (AD), where MMP9 levels are elevated in the brain and cerebrovasculature. Previously o...
Citation: BMC Neuroscience 2021 22:39 -
Overexpression of the receptor for advanced glycation end-products in the auditory cortex of rats with noise-induced hearing loss
The receptor for advanced glycation end-products (RAGE) is involved in neuroinflammation. This study investigated the changes in RAGE expression following noise-induced hearing loss.
Citation: BMC Neuroscience 2021 22:38 -
Causal relationship of CA3 back-projection to the dentate gyrus and its role in CA1 fast ripple generation
Pathophysiological evidence from temporal lobe epilepsy models highlights the hippocampus as the most affected structure due to its high degree of neuroplasticity and control of the dynamics of limbic structur...
Citation: BMC Neuroscience 2021 22:37 -
Inhibitory control training reveals a common neurofunctional basis for generic executive functions and language switching in bilinguals
The neural networks underpinning language control and domain-general executive functions overlap in bilinguals, but existing evidence is mainly correlative. Here, we present the first neurofunctional evidence ...
Citation: BMC Neuroscience 2021 22:36 -
Impairments in brain perfusion, executive control network, topological characteristics, and neurocognition in adult patients with asymptomatic Moyamoya disease
Asymptomatic Moyamoya disease (MMD) impairs hemodynamic and cognitive function. The relationship between these changes, cerebral blood flow (CBF), and network connectivity remains largely unknown. The aim of t...
Citation: BMC Neuroscience 2021 22:35 -
Time spent on the smartphone does not relate to manual dexterity in young adults
The Grooved Pegboard Test (GPT) is widely adopted to evaluate manual dexterity, it presents normative data but the test is influenced by different factors. The influence of time spent on smartphones has not be...
Citation: BMC Neuroscience 2021 22:34 -
Comparative analysis of spreading depolarizations in brain slices exposed to osmotic or metabolic stress
Recurrent spreading depolarizations (SDs) occur in stroke and traumatic brain injury and are considered as a hallmark of injury progression. The complexity of conditions associated with SD in the living brain ...
Citation: BMC Neuroscience 2021 22:33 -
Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism
Autism spectrum disorder (ASD) is characterized by the core symptoms of impaired social interactions. Increasing evidence suggests that ASD has a strong genetic link with mutations in chromodomain helicase DNA...
Citation: BMC Neuroscience 2021 22:32 -
Lung-protective ventilation increases cerebral metabolism and non-inflammatory brain injury in porcine experimental sepsis
Protective ventilation with lower tidal volumes reduces systemic and organ-specific inflammation. In sepsis-induced encephalopathy or acute brain injury the use of protective ventilation has not been widely in...
Citation: BMC Neuroscience 2021 22:31 -
A short-term musical training affects implicit emotion regulation only in behaviour but not in brain activity
In everyday life, negative emotions can be implicitly regulated by positive stimuli, without any conscious cognitive engagement; however, the effects of such implicit regulation on mood and related neuro-mecha...
Citation: BMC Neuroscience 2021 22:30 -
Concentrations of estradiol, progesterone and testosterone in serum and cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage correlate weakly with transcranial Doppler flow velocities
The implication of the steroids estradiol, progesterone and testosterone in cerebral vasospasm after aneurysmal subarachnoid hemorrhage (aSAH) has not been comprehensively assessed. In rodents, studies suggest...
Citation: BMC Neuroscience 2021 22:29 -
Early postnatal irradiation‐induced age‐dependent changes in adult mouse brain: MRI based characterization
Brain radiation exposure, in particular, radiotherapy, can induce cognitive impairment in patients, with significant effects persisting for the rest of their life. However, the main mechanisms leading to this ...
Citation: BMC Neuroscience 2021 22:28 -
Correction to: Protective effects of intracerebroventricular adiponectin against olfactory impairments in an amyloid β1–42 rat model
An amendment to this paper has been published and can be accessed via the original article.
Citation: BMC Neuroscience 2021 22:27 -
Transcranial direct current stimulation for balance and gait in repetitive mild traumatic brain injury in rats
Balance impairment and lack of postural orientation are serious problems in patients with repetitive mild traumatic brain injury (mTBI).
Citation: BMC Neuroscience 2021 22:26 -
N/OFQ modulates orofacial pain induced by tooth movement through CGRP-dependent pathways
Nociceptin/orphanin FQ (N/OFQ) has been revealed to play bidirectional roles in orofacial pain modulation. Calcitonin gene-related peptide (CGRP) is a well-known pro-nociceptive molecule that participates in t...
Citation: BMC Neuroscience 2021 22:25 -
Behavioral sensitization induced by methamphetamine causes differential alterations in gene expression and histone acetylation of the prefrontal cortex in rats
Methamphetamine (METH) is one of the most widely abused illicit substances worldwide; unfortunately, its addiction mechanism remains unclear. Based on accumulating evidence, changes in gene expression and chro...
Citation: BMC Neuroscience 2021 22:24 -
Spinal reflexive movement follows general tau theory
Tau theory explains how both intrinsically and perceptually guided movements are controlled by the brain. According to general tau theory, voluntary, self-paced human movements are controlled by coupling the t...
Citation: BMC Neuroscience 2021 22:23 -
Sex effects on clinical features in LRRK2 G2385R carriers and non-carriers in Parkinson's disease
Differences of genotypes between male and female have been studied in Parkinson’s disease (PD), but limited research has focused on the comparison between sexes with LRRK2 G2385 variant.
Citation: BMC Neuroscience 2021 22:22 -
Ammonia induced microglia activation was associated with limited effects on connexin 43 and aquaporin 4 expression in an astrocyte-microglia co-culture model
Hepatic encephalopathy (HE) is a neurological complication resulting from acute or chronic liver disease. Hyperammonemia leading to astrocyte swelling and cerebral edema in combination with neuroinflammation i...
Citation: BMC Neuroscience 2021 22:21 -
Association between the vertebrobasilar artery geometry and basilar artery plaques determined by high-resolution magnetic resonance imaging
Atherosclerotic plaques are often present in regions of arteries with complicated flow patterns. Vascular morphology plays important role in hemodynamics. In this study, we investigated the relationship betwee...
Citation: BMC Neuroscience 2021 22:20 -
Framing and self-responsibility modulate brain activities in decision escalation
Escalation of commitment is a common bias in human decision making. The present study examined (1) differences in neural recruitment for escalation and de-escalation decisions of prior investments, and (2) how...
Citation: BMC Neuroscience 2021 22:19 -
SCN11A gene deletion causes sensorineural hearing loss by impairing the ribbon synapses and auditory nerves
The SCN11A gene, encoded Nav1.9 TTX resistant sodium channels, is a main effector in peripheral inflammation related pain in nociceptive neurons. The role of SCN11A gene in the auditory system has not been well c...
Citation: BMC Neuroscience 2021 22:18 -
The role of mGlu4 receptors within the nucleus accumbens in acquisition and expression of morphine-induced conditioned place preference in male rats
Several studies have shown that glutamate neurotransmission in the nucleus accumbens (NAc) is required for the development of morphine-induced conditional place preference (CPP). In addition, metabotropic glut...
Citation: BMC Neuroscience 2021 22:17 -
Correction to: Eye-tracking-aided characterization of saccades and antisaccades in SYNE1 ataxia patients: a pilot study
An amendment to this paper has been published and can be accessed via the original article.
Citation: BMC Neuroscience 2021 22:16 -
Construction of competitive endogenous RNA network reveals regulatory role of long non-coding RNAs in intracranial aneurysm
Rupture of intracranial aneurysm (IA) is the main cause of devastating subarachnoid hemorrhage, which urges our understanding of the pathogenesis and regulatory mechanisms of IA. However, the regulatory roles ...
Citation: BMC Neuroscience 2021 22:15
Annual Journal Metrics
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Citation Impact 2023
Journal Impact Factor: 2.4
5-year Journal Impact Factor: 2.9
Source Normalized Impact per Paper (SNIP): 0.634
SCImago Journal Rank (SJR): 0.666
Speed 2023
Submission to first editorial decision (median days): 16
Submission to acceptance (median days): 136
Usage 2023
Downloads: 1,148,240
Altmetric mentions: 1,031