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- Open Access
Effects of a reduced efficacy of the KCC2 co-transporter in temporal lobe epilepsy: single neuron and network study
- Published: 4 December 2015
Keywords
- Neural Network Model
- Pyramidal Cell
- Temporal Lobe Epilepsy
- Potassium Level
- Ionic Homeostasis
A raster plot of pyramidal cell population firing; B raster plot of interneuron firing; C spatial distribution of extracellular potassium; D intracellular chloride distribution.
Declarations
Acknowledgements
This work has been supported by the following grants: ANR-10-LABX-0087 IEC, ANR-10-IDEX-0001-02 PSL, ERC-322721, FRM FDT20140930942. Especially we would like to thank Giri Krishnan for useful discussions.
Authors’ Affiliations
References
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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.