Observations of dynamical behavior in a stochastic Wilson-Cowan population with plasticity
BMC Neuroscience volume 14, Article number: P400 (2013)
Understanding network connectivity and its role in brain activity is an arduous task. Complicating matters further is the introduction of synaptic plasticity rules. Observations using a mean-field perspective  are by their nature incomplete so, here, a stochastic model, which includes fluctuations, has been employed. This analysis shows that two types of network connections, driven by plasticity, exhibit oscillatory behavior signaled by a flipping between Up and Down states. Fluctuations in each state in both setups display power law-like avalanche distributions.
This study, employing a stochastic algorithm  used previously in a population-based model , introduces plasticity, according to a modified version of , into both an E → E and I → E network (Figure 1A). The former network includes plastic excitatory, anti-Hebbian synapses, connecting the populations, while the latter contains plastic inhibitory Hebbian synapses. Both networks incorporate a constant recurrent excitatory synapse. Dynamically, each network undergoes oscillations of relaxation type (Figure 1B) with fluctuations whose avalanche distributions look like power laws (Figure 1C).
Understanding the dynamics of plasticity-driven neural networks is vital. Here, it was shown that a stochastic Wilson-Cowan population connected to an exterior population can naturally exhibit relaxation oscillations. This result with its power law avalanche statistics is a potential sign of self-organized criticality.
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This work was supported by the Dr. Ralph and Marian Falk Medical Research Trust Fund.
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Neuman, J., Kiewiet, B., Cowan, J.D. et al. Observations of dynamical behavior in a stochastic Wilson-Cowan population with plasticity. BMC Neurosci 14 (Suppl 1), P400 (2013). https://doi.org/10.1186/1471-2202-14-S1-P400