Articles
Page 6 of 98
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Citation: BMC Neuroscience 2020 21(Suppl 1):54
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Distraction by a cognitive task has a higher impact on electrophysiological measures compared with conditioned pain modulation
Conditioned pain modulation (CPM) evaluates the effect of a painful conditioning stimulus (CS) on a painful test stimulus (TS). Using painful cutaneous electrical stimulation (PCES) as TS and painful cold wate...
Citation: BMC Neuroscience 2020 21:53 -
Target detection in healthy 4-week old piglets from a passive two-tone auditory oddball paradigm
Passive auditory oddball tests are effort independent assessments that evaluate auditory processing and are suitable for paediatric patient groups. Our goal was to develop a two-tone auditory oddball test pro...
Citation: BMC Neuroscience 2020 21:52 -
Sex-dimorphic neuroestradiol regulation of ventromedial hypothalamic nucleus glucoregulatory transmitter and glycogen metabolism enzyme protein expression in the rat
Ventromedial hypothalamic nucleus (VMN) gluco-regulatory transmission is subject to sex-specific control by estradiol. The VMN is characterized by high levels of aromatase expression.
Citation: BMC Neuroscience 2020 21:51 -
Enriched environment ameliorates adult hippocampal neurogenesis deficits in Tcf4 haploinsufficient mice
Transcription factor 4 (TCF4) has been linked to human neurodevelopmental disorders such as intellectual disability, Pitt-Hopkins Syndrome (PTHS), autism, and schizophrenia. Recent work demonstrated that TCF4 par...
Citation: BMC Neuroscience 2020 21:50 -
Autistic traits are associated with the functional connectivity of between—but not within—attention systems in the general population
Previous studies have demonstrated that individuals with autism spectrum disorder (ASD) exhibit dysfunction in the three attention systems (i.e., alerting, orienting, and executive control) as well as atypical re...
Citation: BMC Neuroscience 2020 21:49 -
Occipital repetitive transcranial magnetic stimulation does not affect multifocal visual evoked potentials
To identify mechanisms of cortical plasticity of the visual cortex and to quantify their significance, sensitive parameters are warranted. In this context, multifocal visual evoked potentials (mfVEPs) can make...
Citation: BMC Neuroscience 2020 21:48 -
Emotion regulation through bifocal processing of fear inducing and disgust inducing stimuli
We present first-time evidence for the immediate neural and behavioral effects of bifocal emotional processing via visualized tapping for two different types of negative emotions (fear and disgust) in a sample...
Citation: BMC Neuroscience 2020 21:47 -
Crossed cerebellar diaschisis after stroke detected noninvasively by arterial spin-labeling MR imaging
As a noninvasive perfusion-weighted MRI technique, arterial spin-labeling (ASL) was becoming increasingly used to evaluate cerebral hemodynamics in many studies. The relation between ASL-MRI and crossed cerebe...
Citation: BMC Neuroscience 2020 21:46 -
Effect of acute noise trauma on the gene expression profile of the hippocampus
This study aimed to investigate the changes in the expression of hippocampal genes upon acute noise exposure.
Citation: BMC Neuroscience 2020 21:45 -
Correction to: Gender differences in nerve regeneration after sciatic nerve injury and repair in healthy and in type 2 diabetic Goto-Kakizaki rats
An amendment to this paper has been published and can be accessed via the original article.
Citation: BMC Neuroscience 2020 21:44 -
Neurologic effects of short-term treatment with a soluble epoxide hydrolase inhibitor after cardiac arrest in pediatric swine
Cardiac arrest (CA) is the most common cause of acute neurologic insult in children. Many survivors have significant neurocognitive deficits at 1 year of recovery. Epoxyeicosatrienoic acids (EETs) are multifun...
Citation: BMC Neuroscience 2020 21:43 -
Does conserved domain SOD1 mutation has any role in ALS severity and therapeutic outcome?
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative fatal disease that can affect the neurons of brain and spinal cord. ALS genetics has identified various genes to be associated with diseas...
Citation: BMC Neuroscience 2020 21:42 -
Sensory gating and suppression of subjective peripheral sensations during voluntary muscle contraction
During voluntary muscle contraction, sensory information induced by electrostimulation of the nerves supplying the contracting muscle is inhibited and the somatosensory evoked potentials (SEPs) amplitude decre...
Citation: BMC Neuroscience 2020 21:41 -
Autoreceptor control of serotonin dynamics
Serotonin is a neurotransmitter that has been linked to a wide variety of behaviors including feeding and body-weight regulation, social hierarchies, aggression and suicidality, obsessive compulsive disorder, ...
Citation: BMC Neuroscience 2020 21:40 -
Aberrant functional connectivity in resting state networks of ADHD patients revealed by independent component analysis
ADHD is one of the most common psychiatric disorders in children and adolescents. Altered functional connectivity has been associated with ADHD symptoms. This study aimed to investigate abnormal changes in the...
Citation: BMC Neuroscience 2020 21:39 -
NGF receptors and PI3K/AKT pathway involved in glucose fluctuation-induced damage to neurons and α-lipoic acid treatment
Glucose fluctuation promotes neuronal apoptosis, which plays a central role in diabetic encephalopathy (DE). Nerve growth factor (NGF), and its interaction with high-affinity (TrkA) and low-affinity (p75NTR) r...
Citation: BMC Neuroscience 2020 21:38 -
Distributed causality in resting-state network connectivity in the acute and remitting phases of RRMS
Although previous studies have shown that intra-network abnormalities in brain functional networks are correlated with clinical/cognitive impairment in multiple sclerosis (MS), there is little information rega...
Citation: BMC Neuroscience 2020 21:37 -
Isolation and characterization of antibody fragments selective for human FTD brain derived TDP-43 variants
Frontotemporal dementia (FTD) is the second leading cause of early onset dementia following Alzheimer’s disease. It involves atrophy of the frontal and temporal regions of the brain affecting language, memory,...
Citation: BMC Neuroscience 2020 21:36 -
Inter-scanner reproducibility of brain volumetry: influence of automated brain segmentation software
The inter-scanner reproducibility of brain volumetry is important in multi-site neuroimaging studies, where the reliability of automated brain segmentation (ABS) tools plays an important role. This study aimed...
Citation: BMC Neuroscience 2020 21:35 -
Median nerve conduction studies in rabbits
When planning nerve conduction studies using animal models, the sciatic nerve is often used and the upper extremity nerves are not preferred due to the size of laboratory animals. This study aimed to present t...
Citation: BMC Neuroscience 2020 21:34 -
MicroRNA-138 promotes neuroblastoma SH-SY5Y cell apoptosis by directly targeting DEK in Alzheimer’s disease cell model
Alzheimer’s disease (AD) is a progressive neuro-degenerative disease with a major manifestation of dementia. MicroRNAs were reported to regulate the transcript expression in patients with Alzheimer’s disease (...
Citation: BMC Neuroscience 2020 21:33 -
Opposing effects of antibiotics and germ-free status on neuropeptide systems involved in social behaviour and pain regulation
Recent research has revealed that the community of microorganisms inhabiting the gut affects brain development, function and behaviour. In particular, disruption of the gut microbiome during critical developme...
Citation: BMC Neuroscience 2020 21:32 -
Genome-wide epigenetic analyses in Japanese immigrant plantation workers with Parkinson’s disease and exposure to organochlorines reveal possible involvement of glial genes and pathways involved in neurotoxicity
Parkinson’s disease (PD) is a disease of the central nervous system that progressively affects the motor system. Epidemiological studies have provided evidence that exposure to agriculture-related occupations ...
Citation: BMC Neuroscience 2020 21:31 -
Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study
One of the most basic human traits is language. Linguistic ability, and disability, have been shown to have a strong genetic component in family and twin studies, but molecular genetic studies of language phen...
Citation: BMC Neuroscience 2020 21:30 -
Neuroprotective effects of magnesium l-threonate in a hypoxic zebrafish model
Hypoxia inhibits the uptake of glutamate (a major neurotransmitter in the brain closely related to cognitive function) into brain cells, and the initial response of cells to cortical hypoxia depends on glutama...
Citation: BMC Neuroscience 2020 21:29 -
NeuroConstruct-based implementation of structured-light stimulated retinal circuitry
Retinal circuitry provides a fundamental window to neural networks, featuring widely investigated visual phenomena ranging from direction selectivity to fast detection of approaching motion. As the divide betw...
Citation: BMC Neuroscience 2020 21:28 -
Hcfc1a regulates neural precursor proliferation and asxl1 expression in the developing brain
Precise regulation of neural precursor cell (NPC) proliferation and differentiation is essential to ensure proper brain development and function. The HCFC1 gene encodes a transcriptional co-factor that regulates ...
Citation: BMC Neuroscience 2020 21:27 -
Anodal transcranial direct current stimulation reduces motor slowing in athletes and non-athletes
Motor fatigability describes a phenomenon that occurs when exhaustive exercise or physically demanding tasks are executed over an extended period of time. Concerning fast repetitive movements, it is noticeable...
Citation: BMC Neuroscience 2020 21:26 -
Repeated social defeat promotes persistent inflammatory changes in splenic myeloid cells; decreased expression of β-arrestin-2 (ARRB2) and increased expression of interleukin-6 (IL-6)
Previous studies suggest that persistent exposure to social stress in mammals may be associated with multiple physiological effects. Here, we examine the effects of social stress in rats, i.e. repeated social ...
Citation: BMC Neuroscience 2020 21:25 -
Dl-3-n-Butylphthalide promotes neovascularization and neurological recovery in a rat model of intracerebral hemorrhage
Cerebral stroke occurs following ischemic and hemorrhagic lesions in the brain. Survival and recovery of stroke patients depend on the severity of the initial injury but also the therapeutic approaches applied...
Citation: BMC Neuroscience 2020 21:24 -
Alexithymia and automatic processing of facial emotions: behavioral and neural findings
Alexithymia is a personality trait characterized by difficulties identifying and describing feelings, an externally oriented style of thinking, and a reduced inclination to imagination. Previous research has s...
Citation: BMC Neuroscience 2020 21:23 -
Resuscitation with macromolecular superoxide dismutase/catalase mimetic polynitroxylated PEGylated hemoglobin offers neuroprotection in guinea pigs after traumatic brain injury combined with hemorrhage shock
Polynitroxylated PEGylated hemoglobin (PNPH, aka SanFlow) possesses superoxide dismutase/catalase mimetic activities that may directly protect the brain from oxidative stress. Stabilization of PNPH with bound ...
Citation: BMC Neuroscience 2020 21:22 -
Cathodal tDCS exerts neuroprotective effect in rat brain after acute ischemic stroke
Transcranial direct current stimulation (tDCS) is a non-invasive brain modulation technique that has been proved to exert beneficial effects in the acute phase of stroke. To explore the underlying mechanism, w...
Citation: BMC Neuroscience 2020 21:21 -
The impact of mental fatigue on brain activity: a comparative study both in resting state and task state using EEG
Mental fatigue is usually caused by long-term cognitive activities, mainly manifested as drowsiness, difficulty in concentrating, decreased alertness, disordered thinking, slow reaction, lethargy, reduced work...
Citation: BMC Neuroscience 2020 21:20 -
Conformity-like behaviour in mice observing the freezing of other mice: a model of empathy
Empathy refers to the ability to recognise and share emotions with others. Several research groups have recognised observational fear in mice as a useful behavioural model for assessing their ability to empath...
Citation: BMC Neuroscience 2020 21:19 -
COX5A over-expression protects cortical neurons from hypoxic ischemic injury in neonatal rats associated with TPI up-regulation
Neonatal hypoxic-ischemic encephalopathy (HIE) represents as a major cause of neonatal morbidity and mortality. However, the underlying molecular mechanisms in brain damage are still not fully elucidated. This...
Citation: BMC Neuroscience 2020 21:18 -
Correction to: The role of C-afferents in mediating neurogenic vasodilatation in plantar skin after acute sciatic nerve injury in rats
An amendment to this paper has been published and can be accessed via the original article.
Citation: BMC Neuroscience 2020 21:17 -
Noise exposure alters MMP9 and brevican expression in the rat primary auditory cortex
This study aimed to investigate the changes in molecules related to perineuronal nets (PNNs) and synaptic transporters in the primary auditory cortices of rats with noise-induced hearing loss. Female Sprague–D...
Citation: BMC Neuroscience 2020 21:16 -
The role of C-afferents in mediating neurogenic vasodilatation in plantar skin after acute sciatic nerve injury in rats
Vasomotor regulation of dermal blood vessels, which are critical in the function of the skin in thermoregulatory control, involves both neural and non-neural mechanisms. Whereas the role of sympathetic nerves ...
Citation: BMC Neuroscience 2020 21:15 -
When gratitude and cooperation between friends affect inter-brain connectivity for EEG
Recently several studies in the psychological and social field have investigated the social function of gift exchange as a useful way for the consolidation of interpersonal and social relationships and the imp...
Citation: BMC Neuroscience 2020 21:14 -
Intravenous methylprednisolone or immunoglobulin for anti-glutamic acid decarboxylase 65 antibody autoimmune encephalitis: which is better?
Patients positive for anti-glutamic acid decarboxylase 65 (GAD65) antibodies have attracted increasing attention. Their clinical manifestations are highly heterogeneous and can be comorbid with tumors. Current...
Citation: BMC Neuroscience 2020 21:13 -
Dopamine response gene pathways in dorsal striatum MSNs from a gene expression viewpoint: cAMP-mediated gene networks
Medium spiny neurons (MSNs) comprise the main body (95% in mouse) of the dorsal striatum neurons and represent dopaminoceptive GABAergic neurons. The cAMP (cyclic Adenosine MonoPhosphate)—mediated cascade of e...
Citation: BMC Neuroscience 2020 21:12 -
Neuropathological changes in dorsal root ganglia induced by pyridoxine in dogs
Pyridoxine (PDX; vitamin B6), is an essential vitamin. PDX deficiency induces various symptoms, and when PDX is misused it acts as a neurotoxicant, inducing severe sensory neuropathy.
Citation: BMC Neuroscience 2020 21:11 -
Correction to: Wnt3a induces exosome secretion from primary cultured rat microglia
Following the publication of this article [1], it has been noted by the authors that an image of the same cell nuclei has been used in error twice, in Fig. 8, parts A and B. These images are redundant in this ...
Citation: BMC Neuroscience 2020 21:10 -
Neuromyelitis optica: a pilot study of clinical presentation and status of serological biomarker AQP4 among patients admitted to a tertiary centre in NCNS, Sudan
Neuromyelitis optica (NMO) is a demyelinating disease primarily affecting the optic nerves and spinal cord. It is distinguished from other demyelinating conditions by the presence of AQP4-IgG and serum aquapor...
Citation: BMC Neuroscience 2020 21:9 -
Suppression of behavioral activity and hippocampal noradrenaline caused by surgical stress in type 2 diabetes model mice
There has been much discussion recently about the occurrence of neuropsychological complications during the perioperative period. Diabetes is known to be one of the metabolic risk factors. Although the number ...
Citation: BMC Neuroscience 2020 21:8 -
Identifying the pulsed neuron networks’ structures by a nonlinear Granger causality method
It is a crucial task of brain science researches to explore functional connective maps of Biological Neural Networks (BNN). The maps help to deeply study the dominant relationship between the structures of the...
Citation: BMC Neuroscience 2020 21:7 -
Proximity ligation assay reveals both pre- and postsynaptic localization of the APP-processing enzymes ADAM10 and BACE1 in rat and human adult brain
Synaptic degeneration and accumulation of amyloid β-peptides (Aβ) are hallmarks of the Alzheimer diseased brain. Aβ is synaptotoxic and produced by sequential cleavage of the amyloid precursor protein (APP) by...
Citation: BMC Neuroscience 2020 21:6 -
Sexual dimorphism following in vitro ischemia in the response to neurosteroids and mechanisms of injury
Cerebral ischemic stroke is a significant cause of morbidity and mortality. Sex differences exist following stroke in terms of incidence, symptoms, outcomes and response to some treatments. Importantly, molecu...
Citation: BMC Neuroscience 2020 21:5
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