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  1. Alzheimer’s disease (AD) is a primary cause of dementia in ageing population affecting more than 35 million people around the globe. It is a chronic neurodegenerative disease caused by defected folding and agg...

    Authors: Sidra Khalid, Muhammad Ammar Zahid, Hussain Ali, Yeong S. Kim and Salman Khan
    Citation: BMC Neuroscience 2018 19:74
  2. The plasma membrane Na+/Ca2+-exchanger (NCX) has recently been shown to regulate Ca2+-dependent N-methyl-d-aspartate receptor (NMDAR) desensitization, suggesting a tight interaction of NCXs and NMDARs in lipid na...

    Authors: Dmitry A. Sibarov, Ekaterina E. Poguzhelskaya and Sergei M. Antonov
    Citation: BMC Neuroscience 2018 19:73
  3. Glycine receptors (GlyRs) are involved in the development of spinal pain sensitization. The GlyRα3 subunit has recently emerged as a key factor in inflammatory pain pathways in the spinal cord dorsal horn (DH)...

    Authors: Hung-Chen Wang, Kuang-I Cheng, Pei-Ru Chen, Kuang-Yi Tseng, Aij-Lie Kwan and Lin-Li Chang
    Citation: BMC Neuroscience 2018 19:72
  4. Neurological disorders suggest that the excitotoxicity involves a drastic increase in intracellular Ca2+ concentrations and the formation of reactive oxygen species. The presence of these free radicals may also a...

    Authors: Armando Valenzuela Peraza, David Calderón Guzmán, Norma Osnaya Brizuela, Maribel Ortiz Herrera, Hugo Juárez Olguín, Miroslava Lindoro Silva, Belén Juárez Tapia and Gerardo Barragán Mejía
    Citation: BMC Neuroscience 2018 19:71
  5. The proteasome system plays an important role in synaptic plasticity. Induction and maintenance of long term potentiation is directly dependent on selective targeting of proteins for proteasomal degradation. T...

    Authors: Julia Adelöf, My Andersson, Michelle Porritt, Anne Petersen, Madeleine Zetterberg, John Wiseman and Malin Hernebring
    Citation: BMC Neuroscience 2018 19:70
  6. FoxP transcription factors play crucial roles for the development and function of vertebrate brains. In humans the neurally expressed FOXPs, FOXP1, FOXP2, and FOXP4 are implicated in cognition, including langu...

    Authors: Adriana Schatton, Julia Agoro, Janis Mardink, Gérard Leboulle and Constance Scharff
    Citation: BMC Neuroscience 2018 19:69
  7. The clinical significance of anti-neuronal antibodies in patients with psychiatric disorders, but without encephalitis, remains unknown. In patients admitted to acute psychiatric inpatient care we aimed to ide...

    Authors: Morten B. Schou, Sverre Georg Sæther, Ole Kristian Drange, Karoline Krane-Gartiser, Solveig K. Reitan, Arne E. Vaaler and Daniel Kondziella
    Citation: BMC Neuroscience 2018 19:68
  8. Tinnitus is the perception of sound in the absence of any external acoustic stimulation. Transcranial direct current stimulation (tDCS) has shown promising though heterogeneous therapeutic outcomes for tinnitu...

    Authors: Tifei Yuan, Ali Yadollahpour, Julio Salgado-Ramírez, Daniel Robles-Camarillo and Rocío Ortega-Palacios
    Citation: BMC Neuroscience 2018 19:66
  9. Social behavior and interactions pervasively shape and influence our lives and relationships. Competition, in particular, has become a core topic in social neuroscience since it stresses the relevance and sali...

    Authors: Michela Balconi and Maria Elide Vanutelli
    Citation: BMC Neuroscience 2018 19:63
  10. Epidemiological surveys and studies with animal models have established a relationship between maternal stress and affective disorders in their offspring. However, whether maternal depression before pregnancy ...

    Authors: Sheng Wei, Zifa Li, Meng Ren, Jieqiong Wang, Jie Gao, Yinghui Guo, Kaiyong Xu, Fang Li, Dehao Zhu, Hao Zhang, Rongju Lv and Mingqi Qiao
    Citation: BMC Neuroscience 2018 19:61
  11. Pulsed transcranial ultrasound stimulation (pTUS) can modulate the neuronal activity of motor cortex and elicit muscle contractions. Cortico-muscular coupling (CMC) can serve as a tool to identify interaction ...

    Authors: Ping Xie, Sa Zhou, Xingran Wang, Yibo Wang and Yi Yuan
    Citation: BMC Neuroscience 2018 19:60
  12. Environmental uncertainty, such as food deprivation, may alter internal milieu of nervous system through various mechanisms. In combination with circumstances of stress or aging, high consumption of unsaturate...

    Authors: Noushin Nikray, Isaac Karimi, Zahraminoosh Siavashhaghighi, Lora A. Becker and Mohammad Mehdi Mofatteh
    Citation: BMC Neuroscience 2018 19:59
  13. Minocycline is a lipophilic tetracycline of increasing appeal in neuroscience as it inhibits microglial activation, a mechanism involved in numerous neuropsychiatric disorders. Own data point towards retinoid-...

    Authors: Vera Clemens, Francesca Regen, Nathalie Le Bret, Isabella Heuser and Julian Hellmann-Regen
    Citation: BMC Neuroscience 2018 19:58
  14. Low-intensity transcranial focused ultrasound (tFUS) has emerged as a new non-invasive modality of brain stimulation with the potential for high spatial selectivity and penetration depth. Anesthesia is typical...

    Authors: Wonhye Lee, Phillip Croce, Ryan W. Margolin, Amanda Cammalleri, Kyungho Yoon and Seung-Schik Yoo
    Citation: BMC Neuroscience 2018 19:57
  15. Transcranial focused ultrasound (tFUS) is a new non-invasive neuromodulation technique that uses mechanical energy to modulate neuronal excitability with high spatial precision. tFUS has been shown to be capab...

    Authors: Leo Ai, Priya Bansal, Jerel K. Mueller and Wynn Legon
    Citation: BMC Neuroscience 2018 19:56
  16. The long-term effects of psychotropic drugs are associated with the reversal of disease-related alterations through the reorganization and normalization of neuronal connections. Molecular factors that trigger ...

    Authors: Magdalena Zygmunt, Dżesika Hoinkis, Jacek Hajto, Marcin Piechota, Bożena Skupień-Rabian, Urszula Jankowska, Sylwia Kędracka-Krok, Jan Rodriguez Parkitna and Michał Korostyński
    Citation: BMC Neuroscience 2018 19:55
  17. Our published data have indicated that the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) provides beneficial effects by attenuating neuronal damage induced by interleukin-1β (IL-1β), and up-re...

    Authors: YiLong Dong, KangJing Pu, WenJing Duan, HuiCheng Chen, LiXing Chen and YanMei Wang
    Citation: BMC Neuroscience 2018 19:52
  18. Adipose tissue is a dynamic organ with different effects on the body. Many of these effects are mediated by leptin, a hormone strongly involved in regulation of feeding and energy metabolism. It has an importa...

    Authors: Laura Mora-Muñoz, Alejandro Guerrero-Naranjo, Elisa Angélica Rodríguez-Jimenez, Claudio Alberto Mastronardi and Alberto Velez-van-Meerbeke
    Citation: BMC Neuroscience 2018 19:51
  19. Spinal cord injury (SCI) is one of the leading causes of disability and chronic pain. In SCI-induced pathology, homeostasis of the nitric oxide (NO) metabolome is lost. Major NO metabolites such as S-nitrosogl...

    Authors: Mushfiquddin Khan, Tajinder S. Dhammu, Inderjit Singh and Avtar K. Singh
    Citation: BMC Neuroscience 2018 19:50
  20. Current antiepileptic drugs are not able to prevent recurrent seizures in all patients. Orexins are excitatory hypothalamic neuropeptides that their receptors (Orx1R and Orx2R) are found almost in all major re...

    Authors: Saeedeh Asadi, Ali Roohbakhsh, Ali Shamsizadeh, Masoud Fereidoni, Elham Kordijaz and Ali Moghimi
    Citation: BMC Neuroscience 2018 19:49
  21. Intracranial Self-Stimulation (ICSS) of the medial forebrain bundle (MFB) is a deep brain stimulation procedure, which has a powerful enhancement effect on explicit and implicit memory. However, the downstream...

    Authors: Elisabet Kádár, Eva Vico Varela, Laura Aldavert-Vera, Gemma Huguet, Ignacio Morgado-Bernal and Pilar Segura-Torres
    Citation: BMC Neuroscience 2018 19:48
  22. The amino acid taurine (2-Aminoethanesulfonic acid) modulates inhibitory neurotransmitter receptors. This study aimed to determine if the dual action of taurine on GABAC-ρ1R relates to its structure. To address t...

    Authors: Lenin David Ochoa-de la Paz, Martin González-Andrade, Herminia Pasantes-Morales, Rodrigo Franco, Rubén Zamora-Alvarado, Edgar Zenteno, Hugo Quiroz-Mercado, Roberto Gonzales-Salinas and Rosario Gulias-Cañizo
    Citation: BMC Neuroscience 2018 19:47
  23. Alzheimer’s disease (AD), the most common cause of dementia, is characterized by the progressive deposition of amyloid-β (Aβ) peptides and neurofibrillary tangles. Mouse models of Aβ amyloidosis generated by k...

    Authors: Yasufumi Sakakibara, Michiko Sekiya, Takashi Saito, Takaomi C. Saido and Koichi M. Iijima
    Citation: BMC Neuroscience 2018 19:46
  24. Although amyloid beta (Aβ) imaging is widely used for diagnosing and monitoring Alzheimer’s disease in clinical fields, paralleling comparison between 18F-flutemetamol and 18F-florbetaben was rarely attempted in ...

    Authors: Hye Joo Son, Young Jin Jeong, Hyun Jin Yoon, Sang Yoon Lee, Go-Eun Choi, Ji-Ae Park, Min Hwan Kim, Kyo Chul Lee, Yong Jin Lee, Mun Ki Kim, Kook Cho and Do-Young Kang
    Citation: BMC Neuroscience 2018 19:45
  25. Given the reported inverse association between light and depressive mood, ambient light may also be associated with some of the brain regions in healthy subjects. The present study aims to investigate the effe...

    Authors: Hirofumi Hirakawa, Takeshi Terao, Koji Hatano, Kentaro Kohno and Nobuyoshi Ishii
    Citation: BMC Neuroscience 2018 19:44
  26. Light exposure induces oxidative stress, which contributes to ocular diseases of aging. Blue light provides a model for light-induced oxidative stress, lipid peroxidation and retinal degeneration in Drosophila me...

    Authors: Hana Hall, Jingqun Ma, Sudhanshu Shekhar, Walter D. Leon-Salas and Vikki M. Weake
    Citation: BMC Neuroscience 2018 19:43
  27. Striatal fast-spiking interneurons (FSI) are a subset of GABAergic cells that express calcium-binding protein parvalbumin (PV). They provide feed-forward inhibition to striatal projection neurons (SPNs), recei...

    Authors: Ernesto Alberto Rendón-Ochoa, Teresa Hernández-Flores, Victor Hugo Avilés-Rosas, Verónica Alejandra Cáceres-Chávez, Mariana Duhne, Antonio Laville, Dagoberto Tapia, Elvira Galarraga and José Bargas
    Citation: BMC Neuroscience 2018 19:42
  28. Many neuropsychiatric disorders develop in early life. Although the mechanisms involved have not been elucidated, it is possible that functional abnormalities of parvalbumin-positive interneurons (PV neurons) ...

    Authors: Hiroshi Ueno, Shunsuke Suemitsu, Shinji Murakami, Naoya Kitamura, Kenta Wani, Yosuke Matsumoto, Motoi Okamoto, Shozo Aoki and Takeshi Ishihara
    Citation: BMC Neuroscience 2018 19:41
  29. Visuospatial attention is executed by the frontoparietal cortical areas of the brain. Damage to these areas can result in visual neglect. We therefore aimed to assess a combination of the greyscales task and r...

    Authors: Katrin Giglhuber, Stefanie Maurer, Claus Zimmer, Bernhard Meyer and Sandro M. Krieg
    Citation: BMC Neuroscience 2018 19:40
  30. Tick-borne encephalitis (TBE) is the main tick-borne viral infection in Eurasia. Its manifestations range from inapparent infections and fevers with complete recovery to debilitating or fatal encephalitis. Th...

    Authors: Martin Palus, Yahya Sohrabi, Karl W. Broman, Hynek Strnad, Matyáš Šíma, Daniel Růžek, Valeriya Volkova, Martina Slapničková, Jarmila Vojtíšková, Lucie Mrázková, Jiří Salát and Marie Lipoldová
    Citation: BMC Neuroscience 2018 19:39
  31. Post-traumatic stress disorder (PTSD) is an important psychological disease that can develop following the physical experience or witnessing of traumatic events. The psychopathological response to traumatic st...

    Authors: Bombi Lee, Insop Shim, Hyejung Lee and Dae-Hyun Hahm
    Citation: BMC Neuroscience 2018 19:38
  32. High-frequency transcutaneous neuromuscular electrical nerve stimulation (TENS) is currently used for the administration of electrical current in denervated muscle to alleviate muscle atrophy and enhance moto...

    Authors: Hong-Lin Su, Chien-Yi Chiang, Zong-Han Lu, Fu-Chou Cheng, Chun-Jung Chen, Meei-Ling Sheu, Jason Sheehan and Hung-Chuan Pan
    Citation: BMC Neuroscience 2018 19:37
  33. Cholinergic hypothesis has been advanced as an etiology of Alzheimer disease (AD) on the basis of the presynaptic deficit found in the diseased brains, and cholinesterase inhibitors (ChEIs) are the treatment o...

    Authors: Yu San Chang, Yu Hsuan Wu, Chin Jen Wang, Shu Hui Tang and Hsiang Lan Chen
    Citation: BMC Neuroscience 2018 19:36
  34. Memory performance of an individual (within the age range: 50–55 years old) showing superior memory abilities (protagonist PR) was compared to an age- and education-matched reference group in a historical fact...

    Authors: Thorsten Fehr, Angelica Staniloiu, Hans J. Markowitsch, Peter Erhard and Manfred Herrmann
    Citation: BMC Neuroscience 2018 19:35
  35. Non-depolarizing magnetic fields, like low frequency-pulsed electromagnetic fields (LF-PEMFs) have shown the ability to modulate living structures, principally by influencing synaptic activity and ion channels...

    Authors: Enrico Premi, Alberto Benussi, Antonio La Gatta, Stefano Visconti, Angelo Costa, Nicola Gilberti, Valentina Cantoni, Alessandro Padovani, Barbara Borroni and Mauro Magoni
    Citation: BMC Neuroscience 2018 19:34
  36. The functional connectivity of the default mode network (DMN) decreases in patients with Alzheimer’s disease (AD) as well as in patients with type 2 diabetes mellitus (T2DM). Altered functional connectivity of...

    Authors: Kenji Ishibashi, Keita Sakurai, Keigo Shimoji, Aya M. Tokumaru and Kenji Ishii
    Citation: BMC Neuroscience 2018 19:33
  37. The progressive neurodegenerative disorder multiple system atrophy (MSA) is characterized by α-synuclein-positive (oligodendro-) glial cytoplasmic inclusions (GCIs). A connection between the abnormal accumulat...

    Authors: Lisa Fellner, Edith Buchinger, Dominik Brueck, Regina Irschick, Gregor K. Wenning and Nadia Stefanova
    Citation: BMC Neuroscience 2018 19:32
  38. Exposure to electromagnetic fields can affect human health, damaging tissues and cell homeostasis. Stress modulates neuronal responses and composition of brain lipids. The aim of this study was to evaluate the...

    Authors: Jesús Martínez-Sámano, Alan Flores-Poblano, Leticia Verdugo-Díaz, Marco Antonio Juárez-Oropeza and Patricia V. Torres-Durán
    Citation: BMC Neuroscience 2018 19:31
  39. Studies have suggested the supplementation of Zinc and Linoleic acid in the management of neurodegenerative disorders but none has investigated the combined effects. Little is known about the neuroprotective e...

    Authors: Ngala Elvis Mbiydzenyuy, Herbert Izo Ninsiima, Miriela Betancourt Valladares and Constant Anatole Pieme
    Citation: BMC Neuroscience 2018 19:29
  40. Auditory function and cochlear morphology have previously been described in a porcine model with spontaneous WS2-like phenotype. In the present study, cochlear histopathology was further investigated in the in...

    Authors: Wei Chen, Qing-Qing Hao, Li–Li Ren, Wei Ren, Hui-sang Lin, Wei-Wei Guo and Shi-Ming Yang
    Citation: BMC Neuroscience 2018 19:28
  41. To investigated distinct manifestations of Sjögren’s syndrome (SS) patients with neurological complications and the potential risk factors associated with neurological complications in SS, and to produce a dis...

    Authors: Wenjing Ye, Siyan Chen, Xinshi Huang, Wei Qin, Ting Zhang, Xiaofang Zhu, Xiaochun Zhu, Chongxiang Lin and Xiaobing Wang
    Citation: BMC Neuroscience 2018 19:26

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