Fig. 3
From: Calmodulin binding proteins and neuroinflammation in multiple neurodegenerative diseases
Calcium-dependent calmodulin binding domains and motifs identified in human neuroinflammation proteins. ABCA7, ATP-binding cassette transporter subfamily A member A7; CD33, Myeloid cell surface antigen CD33; CH3L1/YKL-40, Chitinase-3-like protein 1; CLU, Clusterin; CR1, Complement receptor type 1; EPHA1, Ephrin type-A receptor 1; M4A4E, Membrane-spanning 4-domains subfamily A member 4E; M4A6A, Membrane-spanning 4-domains subfamily A member 6A; NLRP3, NACHT, LRR and PYD domains-containing protein 3; PILRA, Paired immunoglobulin-like type 2 receptor alpha; TREM2, Triggering receptor expressed on myeloid cells 2. 1From O’Day, 2015; reanalyzed here. Green highlights: hydrophobic amino acids associated with binding motifs