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Table 4 Effect of mitoxantrone on motor performance of exercised EAE rats (day 13—day 17)

From: Does physical exercise improve or deteriorate treatment of multiple sclerosis with mitoxantrone? Experimental autoimmune encephalomyelitis study in rats

Parameter

Motor performance (s)

Groups

Day 13

Day 14

Day 15

Day 16

Day 17

CN

1800 ± 0

1800 ± 0

1800 ± 0

1800 ± 0

1800 ± 0

EAE

711 ± 215.5$

625.4 ± 190.2$

599.2 ± 183.0$

540.8 ± 165.9$

453.3 ± 143.5$

MT

711 ± 215.5$

950.7 ± 380.2

664.4 ± 362.0$

1028 ± 350.4

1500 ± 300.0%

  1. Values are presented as mean ± S.D (n = 6) and were analyzed using one-way ANOVA followed by Tukey's Multiple Comparison Test (p < 0.05). As compared with ($) CN and (%) EAE groups. EAE experimental autoimmune encephalomyelitis, CN exercised control, EAE exercised untreated EAE, MT exercised mitoxantrone treated rats
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BMC Neuroscience

ISSN: 1471-2202

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