Fig. 2
From: Memantine ameliorates cognitive deficit in AD mice via enhancement of entorhinal–CA1 projection
Memantine restored LTP impairment in APP/PS1 mice. A Typical fEPSP traces before and after TBS recorded in the different groups. Vertical bar, 0.5 mV; horizontal bar, 20 ms. B Time course of LTP induced in the hippocampal CA1 region of mice in the different groups (n = 6 for each group). C Statistics of LTP induced in the hippocampal CA1 region of mice in the different groups. ∗ p < 0.05 compared with WT mice; #p < 0.05 compared with saline treated APP/PS1 mice. one-way ANOVA, Bonferroni post-tests). Bars represent as mean ± SEM