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Table 1 EC50 and Hill Slope values for human and cat TAS2R38 and TAS2R43

From: A functional comparison of the domestic cat bitter receptors Tas2r38 and Tas2r43 with their human orthologs

  

TAS2R38 published

TAS2R38 human

Tas2r38 cat

TAS2R43 published

TAS2R43 human

Tas2r43 cat

PTC

EC50

1.1 μM [19]

2.3 μM

47 μM

-

-

-

 

Hill Slope

-

1.0

2.6

-

-

-

PROP

EC50

2.1 μM [19]

2.2 μM

-

-

-

-

 

Hill Slope

-

1.59

-

-

-

-

Aloin

EC50

-

-

-

1.2 μM [20]

35 μM

346 μM

 

Hill Slope

-

-

-

-

0.8

1.0

Denatonium

EC50

-

-

-

300 μM [5]

1206μM

217 μM

 

Hill Slope

-

-

-

-

1.3

1.7

Saccharin

EC50

-

-

-

1.7 mM [44]

4.5

mM

 

Hill Slope

-

-

-

-

1.5

-

  1. Values were derived from the data shown graphed in Figs. 2 and 3
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BMC Neuroscience

ISSN: 1471-2202

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