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Table 2 Distances between correlation matrices of AD11 and controls

From: Time dynamics of protein complexes in the AD11 transgenic mouse model for Alzheimer’s disease like pathology

  

Distance: AD11-Control

COMPLEX

Size

d 1

d 3

d 6

d 15

immunoproteasome

14

0.26

0.14

0.2

0.16

(2.22)

(−2.45)

(−0.22)

(0.19)

Mediator-complex

7

0.29

0.2

0.16

0.11

(2.10)

(0.09)

(−1.00)

(1.17)

Wave-2-complex-Rac-activated

4

0.33

0.07

0.33

0.36

(1.98)

(−1.85)

(1.97)

(3.39)

p97-Ufd1-Npl4-IP3-receptor-complex

4

0.34

0.21

0.16

0.20

(2.14)

(0.31)

(−0.56)

(0.86)

Tis7-Sin3-Hdac1-Ncor1-Sap30-complex

4

0.34

0.2

0.12

0.03

(2.14)

(0.16)

(−1.16)

(−1.81)

Axin-Dvl-Gsk-Frat1-complex

4

0.28

0.33

0.13

0.1

(1.20)

(2.17)

(−1.01)

(−0.7)

PYR-complex

10

0.19

0.16

0.17

0.27

(−0.67)

(−1.22)

(−0.98)

(3.20)

PU,1-associated-protein-complex

4

0.21

0.21

0.21

0.3

0.11)

(0.31)

(0.18)

(2.44)

TFIID-complex

7

0.25

0.15

0.17

0.2

(1.09)

(−1.16)

(−0.76)

(2.15)

ORC-complex-origin-recognition-complex

4

0.21

0.18

0.27

0.27

(0.11)

(−0.14)

(1.07)

(1.97)

  1. The distances of AD11 and control matrices at the 4 different time points (1,3,6,15 months of age) are reported in columns (d1, d3, d6, d15) respectively. The z-score of each value is reported in parentheses below the value itself. Size is the number of genes in the complex. Only complexes with size > 3 and with at least a z-score value above 1.9 are reported. Negative z-scores indicate a distance AD11 vs. control matrices smaller than the random expectation. Significant z-scores are highlighted in bold.
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BMC Neuroscience

ISSN: 1471-2202

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