iBrain: a simulation and visualization tool for activation of brain areas on a realistic 3D brain image
© Suzuki et al; licensee BioMed Central Ltd. 2007
Published: 6 July 2007
Many computer models have been developed to simulate a neuron, neural networks, and activation of brain areas aimed at the elucidation of mechanisms of brain functions. In this track there is one clear direction of modeling from a single cell to the whole brain . We developed a simulation and visualization tool, "iBrain", by which we could construct, simulate and visualize a model of the transition of brain activation on a realistic brain anatomical atlas.
To test the simulator, we tried to reproduce the activation patterns of a human's word processing which were measured by MEG (magneto-encephalogram). The reproduced patterns were roughly matched to the patterns from the experiment and we could see them visually on the iBrain.
Simulation and visualization of spatio-temporal activation of brain areas on a realistic 3D brain image can be realized by iBrain. We believe this software can help us to understand the brain function at macroscopic level.