Klein DC, Moore RY, Reppert SM: Suprachiasmatic nucleus: The mind's clock. New York: Oxford University Press. 1991
Google Scholar
Edgar DM: Functional role of the suprachiasmatic nuclei in the regulation of sleep and wakefulness. In: Fatal Familial Insomnia: Inherited prion diseases, sleep and the thalamus. Edited by: Guilleminault C. 1994, New York: Raven Press, Ltd, 203-213.
Google Scholar
Dijk DJ, Czeisler CA: Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans. J Neurosci. 1995, 15: 3526-38.
CAS
PubMed
Google Scholar
Borbely AA, Achermann P: Sleep homeostasis and models of sleep regulation. In: Principles and practice in sleep medicine. Edited by: Kryger MH, Roth T, Dement WC. 2000, Philadelphia: W.B. Saunders, 377-390. 3rd
Google Scholar
Edgar DM, Dement WC, Fuller CA: Effect of SCN lesions on sleep in squirrel monkeys: evidence for opponent processes in sleep-wake regulation. J Neurosci. 1993, 13: 1065-79.
CAS
PubMed
Google Scholar
Mistlberger RE, Bergmann BM, Waldenar W, Rechtschaffen A: Recovery sleep following sleep deprivation in intact and suprachiasmatic nuclei-lesioned rats. Sleep. 1983, 6: 217-33.
CAS
PubMed
Google Scholar
Tobler I, Borbely AA, Groos G: The effect of sleep deprivation on sleep in rats with suprachiasmatic lesions. Neurosci Lett. 1983, 42: 49-54. 10.1016/0304-3940(83)90420-2.
Article
CAS
PubMed
Google Scholar
Trachsel L, Edgar DM, Seidel WF, Heller HC, Dement WC: Sleep homeostasis in suprachiasmatic nuclei-lesioned rats: effects of sleep deprivation and triazolam administration. Brain Res. 1992, 589: 253-61. 10.1016/0006-8993(92)91284-L.
Article
CAS
PubMed
Google Scholar
Wurts SW, Edgar DM: Circadian and homeostatic control of rapid eye movement (REM) sleep: promotion of REM tendency by the suprachiasmatic nucleus. J Neurosci. 2000, 20: 4300-10.
CAS
PubMed
Google Scholar
Franken P, Chollet D, Tafti M: The homeostatic regulation of sleep need is under genetic control. J Neurosci. 2001, 21: 2610-21.
CAS
PubMed
Google Scholar
Huber R, Deboer T, Tobler I: Effects of sleep deprivation on sleep and sleep EEG in three mouse strains: empirical data and simulations. Brain Res. 2000, 857: 8-19. 10.1016/S0006-8993(99)02248-9.
Article
CAS
PubMed
Google Scholar
Edgar DM, Seidel WF: Modafinil induces wakefulness without intensifying motor activity or subsequent rebound hypersomnolence in the rat. J Pharmacol Exp Ther. 1997, 283: 757-769.
CAS
PubMed
Google Scholar
Franken P, Dijk DJ, Tobler I, Borbely AA: Sleep deprivation in rats: effects on EEG power spectra, vigilance states, and cortical temperature. Am J Physiol. 1991, 261: R198-208.
CAS
PubMed
Google Scholar
Daan S, Beersma DG, Borbely AA: Timing of human sleep: recovery process gated by a circadian pacemaker. Am J Physiol. 1984, 246: R161-83.
CAS
PubMed
Google Scholar
Cirelli C: How sleep deprivation affects gene expression in the brain: a review of recent findings. J Appl Physiol. 2002, 92: 394-400.
CAS
PubMed
Google Scholar
Shaw PJ, Tononi G, Greenspan RJ, Robinson DF: Stress response genes protect against lethal effects of sleep deprivation in Drosophila. Nature. 2002, 417: 287-91. 10.1038/417287a.
Article
CAS
PubMed
Google Scholar
Shaw PJ, Cirelli C, Greenspan RJ, Tononi G: Correlates of sleep and waking in Drosophila melanogaster. Science. 2000, 287: 1834-7. 10.1126/science.287.5459.1834.
Article
CAS
PubMed
Google Scholar
Hendricks JC, Finn SM, Panckeri KA, Chavkin J, Williams JA, Sehgal A, Pack AI: Rest in Drosophila is a sleep-like state. Neuron. 2000, 25: 129-38.
Article
CAS
PubMed
Google Scholar
Kume K, Zylka MJ, Sriram S, Shearman LP, Weaver DR, Jin X, Maywood ES, Hastings MH, Reppert SM: mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop. Cell. 1999, 98: 193-205.
Article
CAS
PubMed
Google Scholar
Shearman LP, Sriram S, Weaver DR, Maywood ES, Chaves I, Zheng B, Kume K, Lee CC, van der Horst GT, Hastings MH, et al: Interacting molecular loops in the mammalian circadian clock. Science. 2000, 288: 1013-9. 10.1126/science.288.5468.1013.
Article
CAS
PubMed
Google Scholar
Reppert SM, Weaver DR: Molecular analysis of mammalian circadian rhythms. Annu Rev Physiol. 2001, 63: 647-76. 10.1146/annurev.physiol.63.1.647.
Article
CAS
PubMed
Google Scholar
van der Horst GT, Muijtjens M, Kobayashi K, Takano R, Kanno S, Takao M, de Wit J, Verkerk A, Eker AP, van Leenen D, et al: Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms. Nature. 1999, 398: 627-30. 10.1038/19323.
Article
CAS
PubMed
Google Scholar
Vitaterna MH, Selby CP, Todo T, Niwa H, Thompson C, Fruechte EM, Hitomi K, Thresher RJ, Ishikawa T, Miyazaki J, et al: Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2. Proc Natl Acad Sci U S A. 1999, 96: 12114-9. 10.1073/pnas.96.21.12114.
Article
PubMed Central
CAS
PubMed
Google Scholar
Rutter J, Reick M, Wu LC, McKnight SL: Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors. Science. 2001, 293: 510-4. 10.1126/science.1060698.
Article
CAS
PubMed
Google Scholar
Okamura H, Miyake S, Sumi Y, Yamaguchi S, Yasui A, Muijtjens M, Hoeijmakers JH, van der Horst GT: Photic induction of mPer1 and mPer2 in cry-deficient mice lacking a biological clock. Science. 1999, 286: 2531-4. 10.1126/science.286.5449.2531.
Article
CAS
PubMed
Google Scholar
Ripperger JA, Shearman LP, Reppert SM, Schibler U: CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP. Genes Dev. 2000, 14: 679-89.
PubMed Central
CAS
PubMed
Google Scholar
Griffin EA, Staknis D, Weitz CJ: Light-independent role of CRY1 and CRY2 in the mammalian circadian clock. Science. 1999, 286: 768-71. 10.1126/science.286.5440.768.
Article
CAS
PubMed
Google Scholar
Albus H, Bonnefont X, Chaves I, Yasui A, Doczy J, van der Horst GT, Meijer JH: Cryptochrome-deficient mice lack circadian electrical activity in the suprachiasmatic nuclei. Current biology : CB. 2002, 12 (13): 1130-3. 10.1016/S0960-9822(02)00923-5.
Article
CAS
PubMed
Google Scholar
Zheng B, Albrecht U, Kaasik K, Sage M, Lu W, Vaishnav S, Li Q, Sun ZS, Eichele G, Bradley A, et al: Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell. 2001, 105: 683-94. 10.1016/S0092-8674(01)00380-4.
Article
CAS
PubMed
Google Scholar
Bunger MK, Wilsbacher LD, Moran SM, Clendenin C, Radcliffe LA, Hogenesch JB, Simon MC, Takahashi JS, Bradfield CA: Mop3 is an essential component of the master circadian pacemaker in mammals. Cell. 2000, 103: 1009-17.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ibuka N, Nihonmatsu I, Sekiguchi S: Sleep-wakefulness rhythms in mice after suprachiasmatic nucleus lesions. Waking Sleeping. 1980, 4: 167-73.
CAS
PubMed
Google Scholar
Borbely AA: A two process model of sleep regulation. Hum Neurobiol. 1982, 1: 195-204.
CAS
PubMed
Google Scholar
Vitaterna MH, King DP, Chang AM, Kornhauser JM, Lowrey PL, McDonald JD, Dove WF, Pinto LH, Turek FW, Takahashi JS: Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science. 1994, 264: 719-725.
Article
PubMed Central
CAS
PubMed
Google Scholar
Naylor E, Bergmann BM, Krauski K, Zee PC, Takahashi JS, Vitaterna MH, Turek FW: The circadian clock mutation alters sleep homeostasis in the mouse. J Neurosci. 2000, 20: 8138-43.
CAS
PubMed
Google Scholar
Lopez-Molina L, Conquet F, Dubois-Dauphin M, Schibler U: The DBP gene is expressed according to a circadian rhythm in the suprachiasmatic nucleus and influences circadian behavior. Embo J. 1997, 16: 6762-71. 10.1093/emboj/16.22.6762.
Article
PubMed Central
CAS
PubMed
Google Scholar
Franken P, Lopez-Molina L, Marcacci L, Schibler U, Tafti M: The transcription factor DBP affects circadian sleep consolidation and rhythmic EEG activity. J Neurosci. 2000, 20: 617-25.
CAS
PubMed
Google Scholar
Reick M, Garcia JA, Dudley C, McKnight SL: NPAS2: an analog of clock operative in the mammalian forebrain. Science. 2001, 293: 506-9. 10.1126/science.1060699.
Article
CAS
PubMed
Google Scholar
Yagita K, Tamanini F, Yasuda M, Hoeijmakers JH, van Der Horst GT, Okamura H: Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein. Embo J. 2002, 21: 1301-1314. 10.1093/emboj/21.6.1301.
Article
PubMed Central
CAS
PubMed
Google Scholar
Selby C, Thompson C, Schmitz T, Van Gelder R, S A: Functional redundancy of cryptochromeand classical photoreceptors for nonvisual ocular photoreception in mice. Proc Natl Acad Sci, USA. 2000.
Google Scholar
Albrecht U, Sun ZS, Eichele G, Lee CC: A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light. Cell. 1997, 91: 1055-1064.
Article
CAS
PubMed
Google Scholar
Shigeyoshi Y, Taguchi K, Yamamoto S, Takekida S, Yan L, Tei H, Moriya T, Shibata S, Loros JJ, Dunlap JC, et al: Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript. Cell. 1997, 91: 1043-1053.
Article
CAS
PubMed
Google Scholar
Yokota S, Yamamoto M, Moriya T, Akiyama M, Fukunaga K, Miyamoto E, Shibata S: Involvement of calcium-calmodulin protein kinase but not mitogen-activated protein kinase in light-induced phase delays and Per gene expression in the suprachiasmatic nucleus of the hamster. J Neurochem. 2001, 77: 618-27. 10.1046/j.1471-4159.2001.00270.x.
Article
CAS
PubMed
Google Scholar
Tischkau SA, Mitchell JW, Tyan SH, Buchanan GF, Gillette MU: CREB-dependent activation of Per1 is required for light-induced signaling in the suprachiasmatic nucleus circadian clock. J Biol Chem. 2002
Google Scholar
Gau D, Lemberger T, von Gall C, Kretz O, Le Minh N, Gass P, Schmid W, Schibler U, Korf HW, Schutz G: Phosphorylation of CREB Ser142 regulates light-induced phase shifts of the circadian clock. Neuron. 2002, 34: 245-53.
Article
CAS
PubMed
Google Scholar
Cirelli C, Tononi G: Gene expression in the brain across the sleep-waking cycle. Brain Res. 2000, 885: 303-21. 10.1016/S0006-8993(00)03008-0.
Article
CAS
PubMed
Google Scholar
Lee C, Etchegaray JP, Cagampang FR, Loudon AS, Reppert SM: Posttranslational mechanisms regulate the mammalian circadian clock. Cell. 2001, 107: 855-67.
Article
CAS
PubMed
Google Scholar
Oishi K, Fukui H, Ishida N: Rhythmic expression of BMAL1 mRNA is altered in Clock mutant mice: differential regulation in the suprachiasmatic nucleus and peripheral tissues. Biochem Biophys Res Commun. 2000, 268: 164-71. 10.1006/bbrc.1999.2054.
Article
CAS
PubMed
Google Scholar
Yamaguchi S, Mitsui S, Yan L, Yagita K, Miyake S, Okamura H: Role of DBP in the circadian oscillatory mechanism. Mol Cell Biol. 2000, 20: 4773-81. 10.1128/MCB.20.13.4773-4781.2000.
Article
PubMed Central
CAS
PubMed
Google Scholar
Abe H, Honma S, Namihira M, Masubuchi S, Honma K: Behavioural rhythm splitting in the CS mouse is related to clock gene expression outside the suprachiasmatic nucleus. Eur J Neurosci. 2001, 14: 1121-8. 10.1046/j.0953-816x.2001.01732.x.
Article
CAS
PubMed
Google Scholar
Mrosovsky N, Edelstein K, Hastings MH, Maywood ES: Cycle of period gene expression in a diurnal mammal (Spermophilus tridecemlineatus): implications for nonphotic phase shifting. J Biol Rhythms. 2001, 16: 471-8.
Article
CAS
PubMed
Google Scholar
Masubuchi S, Honma S, Abe H, Ishizaki K, Namihira M, Ikeda M, Honma K: Clock genes outside the suprachiasmatic nucleus involved in manifestation of locomotor activity rhythm in rats. Eur J Neurosci. 2000, 12: 4206-14. 10.1046/j.1460-9568.2000.01313.x.
CAS
PubMed
Google Scholar
Wakamatsu H, Yoshinobu Y, Aida R, Moriya T, Akiyama M, Shibata S: Restricted-feeding-induced anticipatory activity rhythm is associated with a phase-shift of the expression of mPer1 and mPer2 mRNA in the cerebral cortex and hippocampus but not in the suprachiasmatic nucleus of mice. Eur J Neurosci. 2001, 13: 1190-6. 10.1046/j.0953-816x.2001.01483.x.
Article
CAS
PubMed
Google Scholar
Abe M, Herzog ED, Yamazaki S, Straume M, Tei H, Sakaki Y, Menaker M, Block GD: Circadian rhythms in isolated brain regions. J Neurosci. 2002, 22: 350-6.
CAS
PubMed
Google Scholar
Kopp C, Albrecht U, Zheng B, Tobler I: Homeostatic sleep regulation is preserved in mPer1 and mPer2 mutant mice. Eur J Neurosci. 2002, 16: 1099-106. 10.1046/j.1460-9568.2002.02156.x.
Article
PubMed
Google Scholar
Benington JH, Heller HC: Restoration of brain energy metabolism as the function of sleep. Prog Neurobiol. 1995, 45: 347-360. 10.1016/0301-0082(94)00057-O.
Article
CAS
PubMed
Google Scholar
Edgar DM, Kilduff TS, Martin CE, Dement WC: Influence of running wheel activity on free-running sleep/wake and drinking circadian rhythms in mice. Physiol Behav. 1991, 50: 373-378. 10.1016/0031-9384(91)90080-8.
Article
CAS
PubMed
Google Scholar
Franken P, Malafosse A, Tafti M: Genetic determinants of sleep regulation in inbred mice. Sleep. 1999, 22: 155-69.
CAS
PubMed
Google Scholar
O'Hara BF, Watson FL, Srere HK, Kumar H, Wiler SW, Welch SK, Bitting L, Heller HC, Kilduff TS: Gene expression in the brain across the hibernation cycle. J Neurosci. 1999, 19: 3781-90.
PubMed
Google Scholar
Terao A, Peyron C, Ding J, Wurts SW, Edgar DM, Heller HC, Kilduff TS: Prepro-hypocretin (prepro-orexin) expression is unaffected by short-term sleep deprivation in rats and mice. Sleep. 2000, 23: 867-74.
CAS
PubMed
Google Scholar