Key factors dominating the neural coding preference to 1/f signal
© Fan et al. 2015
Published: 18 December 2015
To further reveal the key factors dominating the preference of neuronal dynamics to colored and white noise, we systematically varied the values of Na+ and K+ channel time constants and channel rate constants. Figure 1c showed that the firing rate doesn't change much as a function of sodium activation time constant (τm) for a given 1/f signal (STD = 1). However, the firing rate decrease dramatically with an increase of sodium inactivation time constant (τh) or potassium activation time constant (τn) for this signal. For very large τh and τn, neuronal response dynamics start to be saturate for all signals, see Figure 1d. These results indicate that both sodium inactivation time constant (τh) and potassium activation time constant (τn) may be the key factors dominating neural coding preference to signals with different correlated statistic features.
In sum, this study demonstrated that ionic channel time constant of sodium inactivation and potassium activation may be the dominating factors accounting for the neuronal spiking sensitivity favorable to signals with temporal correlations.
This project is funded by NNSF of China (31271170) and Shanghai Eastern Scholar program SHH1140004).
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