How central inputs and force and velocity feedbacks determine motoneurons activity during voluntary hand movements
© Mazzoni et al. 2015
Published: 18 December 2015
Human hand motion is the result of a complex interplay of motoneurons dynamics, central inputs and feedbacks from the muscles activity. A complete picture of this interplay is still missing, also due to the difficulty of recording motoneuron activity. Thanks to a novel recording method we were able to observe motoneurons spiking activity in the human median nerve during voluntary hand movements. We characterized then the neural dynamics associated to force-varying tasks and to fixed velocity tasks involving different muscles. We used these results to develop a spiking neuron model for the interpretation of the observed relationship between motoneurons firing rate and muscle activity features shedding light on the neural interactions underlying control of hand movements.
This work was supported by FP7-602547 EPIONE, FP7-611687 NEBIAS, Italian Ministry of Health grant NEMESIS, Italian Ministry of University and Research grant HANDBOT, and by Scuola Superiore Sant'Anna.
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