Reconstructing dynamical models from optogenetic data
© Oprisan et al. 2015
Published: 18 December 2015
Optogenetics allows optical control of neuronal activity by using genetically altered neural cells and optical tools. Briefly, optogenetics uses a photosensitive element that, upon absorption of light, produces some change in the activity of the cells. Although the technique evolved, it involves inserting a light-sensitive channel from green algae, called channelrhodopsin-2 (ChR2), into neurons . By precise spatial and temporal delivery of light pulses we can identify the local interconnections among neurons and investigate their dynamical response under different conditions.
Oprisan acknowledges IOS CAREER grant 1054914 from the National Science Foundation.
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