Dissecting estimation of conductances in subthreshold regimes
© Vich and Guillamon; licensee BioMed Central Ltd. 2014
Published: 21 July 2014
Statistics of relative errors in the estimation of total, excitatory and inhibitory conductances.
IAHP – dominated
ILTS – dominated
Mean / Std deviation
8.6% / 6.45%
-11.23% / 9.69%
27.82% / 35.14%
-13.87% / 16.30%
Maximum relative error
Our results add a new warning message when extracting conductance traces from intracellular recordings and the conclusions concerning neuronal activity that can be drawn from them. It also stimulates challenging questions in developing theoretical efficient methods to properly estimate synaptic conductances from voltage traces.
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