- Poster presentation
- Open Access
In vivo connection imaging revealed distinct feedforward and intrinsic neurons in posterior inferotemporal cortex
© Ichiohe et al; licensee BioMed Central Ltd. 2013
- Published: 8 July 2013
- Animal Model
- Injection Site
- Object Recognition
- Parallel System
- Anatomical Imaging
We investigated  circuits for object recognition in macaque anterior (TE) and posterior inferotemporal cortex (TEO), using a two-step method for in vivo anatomical imaging. In step 1, red fluorescent tracer was injected into TE to reveal and Pre-target patches of feedforward neurons in TEO. In step 2, these were visualized on the cortical surface in vivo, and injected with green fluorescent tracer. Histological processing revealed that patches >500 μm from the injection site in TEO consisted of intermingled green TEO-TE intrinsically projecting neurons and red TEO-to-TE neurons, with only few double-labeled neurons. In contrast, patches near the injection site in TEO contained many double-labeled neurons. Two parallel, spatially intermingled circuits are suggested: (1) TEO neurons having very local intrinsic collaterals and projection to TE (2) TEO neurons projecting more widely in the intrinsic network, but not to TE. These parallel systems might be specialized for, respectively, fast vs. highly processed signals.
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