Figure 6
From: MAPK signaling pathway regulates cerebrovascular receptor expression in human cerebral arteries
A. Sections from the human cerebral artery showing pERK immunoreactivity in the smooth muscle cell layer. There are increased expressions of the ERK1/2 protein levels in the cultured arteries compared to the control segments. Treatment with U0126 prevented the increased protein expression in the smooth muscle cells. B. Expression of pERK1/2 protein levels in human cerebral arteries incubated for 48 h with or without the MEK1/2 inhibitor U0126 (5 μM) and control human arteries. Data are expressed as percentage of fresh and given as mean ± s.e.m. *P<0.05, ** P<0.01.