Figure 6
C/EBP siRNA treatment hinders recovery of locomotion activity of the snails following CNS injury. Sham-operated or crush-operated snails were injected with either saline, control siRNA or C/EBP siRNA. The distance that the injured snails crawled in 10 min was measured at various time points (1 day, 5 days, and 10 days) following the nerve crush procedure. On the 10th day, the crush-operated C/EBP siRNA group crawled an average of 4.99 ± 0.71 cm (n = 5) per 10 min which was reduced as compared to the sham-operated saline (10.28 ± 1.28 cm, n = 6), control siRNA (12.23 ± 1.36 cm, n = 6), or C/EBP siRNA (11.56 ± 2.75 cm, n = 5), and crush-operated saline (10.65 ± 2.84 cm, n = 4) or control siRNA treated snails (10.17 ± 1.0 cm, n = 5). Data are presented as mean ± S.E.M. * indicates p < 0.05.