Maximized directed information transfer in critical neuronal networks
© Rubino et al; licensee BioMed Central Ltd. 2011
Published: 18 July 2011
Critical dynamics in complex systems emerge at the transition from random to ordered dynamics and are characterized by power-law distributions of spatial and temporal properties of system events. The occurrence of critical dynamics in neuronal networks is increasingly supported by multielectrode array recordings of spontaneous activity in organotypic cortical slice cultures . System events in these neuronal networks are typically defined as activations of neuronal ensembles, or “neuronal avalanches”. Interestingly, studies associate critical neuronal network avalanche dynamics with optimized information transfer [1, 2]. However, studies have not previously examined the directed nature of information transfer in these networks.
Here, we present three novel transfer-entropy  based measures of directed information transfer between neuronal avalanches. Our measures compute the amount of predictive information present in avalanches properties (avalanche size, avalanche duration and inter-avalanche period) of the source region about avalanche properties of the destination region and are suitable for detecting information transfer at multiple spatial scales, from individual neurons to neuronal ensembles. We apply these measures to compute directed information transfer in large, sparse, modular networks of leaky integrate-and-fire neurons with spike timing-dependent synaptic plasticity and axonal conduction delays. We characterize dynamics in our networks by distributions of neuronal avalanches and assess these distributions for power-law scaling. We compute directed information transfer between two halves of each network, and we normalize this transfer by the null-model transfer, generated by randomly rotating avalanche times for each avalanche vector, and so destroying any present relationships between groups of vectors.
- Beggs JM, Plenz D: Neuronal avalanches in neocortical circuits. J Neurosci. 2003, 23 (35): 11167-11177.PubMedGoogle Scholar
- Shew WL, Yang H, Yu S, Roy R, Plenz D: Information capacity and transmission are maximized in balanced cortical networks with neuronal avalanches. J Neurosci. 2011, 31: 55-63. 10.1523/JNEUROSCI.4637-10.2011.PubMed CentralView ArticlePubMedGoogle Scholar
- Schreiber T: Measuring Information Transfer. Phys Rev Lett. 2000, 85: 461-464. 10.1103/PhysRevLett.85.461.View ArticlePubMedGoogle Scholar
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