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Poster Presentation | Open | Published:

Encoding visual stimuli with a population of Hodgkin-Huxley neurons

In recent years the increasing availability of multi-electrode recordings has led to the application of neural decoding techniques to the recovery of complex stimuli such as natural scenes. A linear decoding algorithm was presented in [1] for the reconstruction of natural scenes with recognizable moving objects using recordings from a neural population of the cat’s Lateral Geniculate Nucleus (LGN).

Most of the current models of encoding in the early visual system (retina, LGN, V1) consist of a linear receptive field followed by a non-linear spike generation mechanism. In [2] we considered a neural circuit architecture consisting of receptive fields in cascade with an equal number of spiking neural circuits. The neural circuits investigated were integrate-and-fire neurons and ON-OFF neurons with random thresholds and feedback. We demonstrated for the first time a decoding algorithm for natural scenes and shown its dependence on the noise level.

Methods

We investigate a neural encoding architecture for visual stimuli consisting of classical receptive fields (center surround or Gabor) in cascade with an ensemble of Hodgkin-Huxley neurons. Recovery of stimuli encoded with an ensemble of Hodgkin-Huxley neurons with known phase response curves was achieved based on the I/O equivalence between Hodgkin-Huxley neurons and Project-Integrate-and-Fire neurons in [3]. The ensemble of Hodgkin-Huxley neurons considered here is assumed to have unknown phase response curves [4]. We provide a visual stimulus reconstruction algorithm based on the spike times generated by the ensemble of Hodgkin-Huxley neurons and demonstrate its performance using natural video sequences (movies). Fig. 1 shows a sample time instant (a frame of a movie) of the reconstructed (left) and the original (right) visual stimulus.

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Figure 1

References

  1. 1.

    Stanley GB, Li FF, Dan Y: Reconstruction of Natural Scenes from Ensemble Responses in the Lateral Geniculate Nucleus. J Neurosci. 1999, 19 (18): 8036-8042.

  2. 2.

    Lazar AA, Pnevmatikakis EA, Zhou Y: Encoding of Natural Scenes with Neural Circuits with Random Thresholds. BNET Technical Report #06-09, Department of Electrical Engineering, Columbia University, New York, NY. 2009

  3. 3.

    Lazar AA: Population Encoding with Hodgkin-Huxley Neurons. IEEE Transactions on Information Theory. 2010, 56 (2): to appear

  4. 4.

    Kim AJ, Lazar AA: Recovery of Stimuli Encoded with a Hodgkin-Huxley Neuron Using Conditional PRCs. In Phase Response Curves in Neuroscience, Springer. Edited by: Nathan W. Schultheiss, Astrid Prinz, and Rob Butera. 2010, to appear

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Acknowledgements

The work presented here was supported by AFOSR under grant number FA9550-09-1-0350.

Author information

Correspondence to Aurel A Lazar.

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Keywords

  • Visual Stimulus
  • Receptive Field
  • Neural Circuit
  • Lateral Geniculate Nucleus
  • Natural Scene