Table 1 List of "apoptosis" genes selectively upregulated in cluster 3

Nr4a2

nuclear receptor subfamily 4, group A, member 2

54278

1.60

4.29

1.30

2.97

6.14

7.39

Fosl1

fos-like antigen 1

25445

1.69

2.09

2.15

2.34

3.02

6.46

Itgav

integrin alpha V

296456

1.39

1.56

2.78

2.38

5.32

5.22

Twist2

twist homolog 2 (Drosophila)

59327

1.42

1.50

1.37

1.58

3.08

4.84

Rarb

retinoic acid receptor, beta

24706

0.89

0.83

1.42

1.80

3.90

4.24

Dusp1

dual specificity phosphatase 1

114856

0.96

1.70

1.89

1.47

2.59

4.16

Hmox1

heme oxygenase (decycling) 1

24451

1.63

2.86

3.07

2.62

2.25

3.71

Angptl4

angiopoietin-like 4

362850

1.23

1.28

1.33

1.98

2.73

3.60

Acin1

apoptotic chromatin condensation inducer 1

305884

0.92

0.67

1.31

2.14

2.68

3.41

Pdgfrb

Platelet derived growth factor receptor, beta polypeptide

24629

0.84

0.77

1.71

1.92

2.99

3.26

Gclc

glutamate-cysteine ligase, catalytic subunit

25283

1.25

1.99

1.58

1.80

2.02

3.01

Ihpk2

inositol hexaphosphate kinase 2

59268

1.07

1.17

1.26

1.64

2.39

2.88

Dapk1

death associated protein kinase 1

306722

0.85

0.95

1.55

1.38

2.70

2.82

Amigo2

adhesion molecule with Ig like domain 2

300186

0.87

0.93

1.00

1.33

1.49

2.81

Mmp2

matrix metallopeptidase 2

81686

1.05

1.12

1.32

1.48

1.92

2.76

Hipk2

Homeodomain interacting protein kinase 2

362342

1.01

1.63

2.14

1.86

2.94

2.69

Birc3

baculoviral IAP repeat-containing 3

78971

1.52

1.63

1.22

1.48

2.27

2.68

Myd116

myeloid differentiation primary response gene 116

171071

1.09

1.90

2.17

1.58

2.95

2.67

Il1rn

interleukin 1 receptor antagonist

60582

1.73

2.51

3.06

1.77

3.57

2.49

Hipk1

homeodomain interacting protein kinase 1

365895

1.12

1.05

1.30

1.37

2.44

2.48

LOC687118

similar to death effector domain-containing DNA binding protein 2

687118

1.58

1.58

2.14

2.00

3.13

2.46

Ripk2

receptor (TNFRSF)-interacting serine-threonine kinase 2

362491

1.04

1.33

1.48

1.69

2.55

2.38

Dapk1

death associated protein kinase 1

306722

0.97

1.00

1.16

1.35

2.16

2.35

Timp3

Tissue inhibitor of metalloproteinase 3

25358

1.16

1.08

1.28

1.01

1.78

2.35

Cln3

ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)

293485

1.17

1.56

2.08

1.50

2.44

2.32

Ercc5

excision repair cross-complementing rodent repair deficiency, complementation group 5

301382

1.05

1.29

1.30

2.06

2.13

2.28

Pik3ca

phosphatidylinositol 3-kinase, catalytic, alpha polypeptide

170911

1.08

1.05

1.45

1.63

2.07

2.20

Raf1

v-raf-leukemia viral oncogene 1

24703

1.13

1.66

1.71

1.73

2.01

2.17

Ednrb

endothelin receptor type B

50672

1.32

1.09

1.46

1.94

1.31

2.15

Cd24

CD24 molecule

25145

0.78

0.61

0.70

0.71

1.39

2.13

Hipk2

homeodomain interacting protein kinase 2

362342

0.93

0.99

1.47

1.35

2.33

2.09

Timp3

Tissue inhibitor of metalloproteinase 3

25358

1.10

0.85

1.13

0.98

1.36

2.08

Vegfa

vascular endothelial growth factor A

83785

0.89

1.20

0.94

1.09

2.02

2.07

Gal

galanin

29141

1.32

1.22

1.85

0.77

1.84

2.03

Furin

furin (paired basic amino acid cleaving enzyme)

54281

1.17

1.20

1.36

1.18

1.89

2.03

Ep300

E1A binding protein p300

170915

1.33

1.09

1.23

1.29

2.28

2.01

Sh3kbp1

SH3-domain kinase binding protein 1

84357

1.03

1.58

1.78

1.47

2.52

1.85

Psen2

presenilin 2

81751

1.37

1.52

2.14

1.91

2.09

1.81

Ptk2b

PTK2 protein tyrosine kinase 2 beta

50646

0.93

1.29

1.95

1.69

2.17

1.81

LOC687813

similar to Tnf receptor-associated factor 1

687813

1.87

2.36

2.35

1.68

2.71

1.75

Ncf1

neutrophil cytosolic factor 1

114553

1.83

2.78

2.72

2.44

2.59

1.75

Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

305338

1.09

1.12

1.48

1.28

2.15

1.74

Cln8

ceroid-lipofuscinosis, neuronal 8

306619

1.52

2.11

2.21

1.77

1.94

1.73

Sh3kbp1

SH3-domain kinase binding protein 1

84357

1.15

1.41

1.47

1.58

2.41

1.72