LFP oscillations provide a time reference for excess spike synchrony among V1 neurons
© Ito et al; licensee BioMed Central Ltd. 2009
Published: 13 July 2009
Based on these findings, we hypothesized that the firing threshold of neurons is effectively modulated in an oscillatory manner due to LFP oscillations. This model predicts that spike synchrony precedes the peak firing rates of the individual neurons, since peak firing rate tends to occur around the trough of the oscillation while the onset of the rate increase (first spikes) should concentrate at the previous, negative slope of the oscillation. Here we show that these predictions hold and that the peak occurrence of UEs indeed occurs at the steepest negative slope of the LFP (Figure 1c, red line). Our observations provide strong support for the interpretation that the beta-band LFP oscillation triggered at saccade-onset reflects an intrinsic, presumably top down, reference signal that enables early visually evoked spikes to precisely lock to this signal. This framework also provides a mechanism to accurately time the spikes of populations of neurons, thereby allowing further processing of visual information via spike synchronization.
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