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Table 6 Gene enrichment WikiPathways analysis of significantly upregulated genes

From: Prodromal Parkinson disease signs are predicted by a whole-blood inflammatory transcriptional signature in young Pink1−/− rats

WikiPathways 2019

P-value

Combined score

Genes

Fatty acid biosynthesis WP336

0.003901842

132.9442998

ACSL1;ECH1

G1 to S cell cycle control WP413

0.027781692

29.05924205

CDKN2C;GADD45A

p53 signaling WP2902

0.033023072

25.09708755

PIDD1;GADD45A

Heme biosynthesis WP18

0.037613345

97.17686109

PPOX

PPAR signaling pathway WP2316

0.046591985

18.55228225

ACSL1;UBC

  1. ACSL1, Acyl-CoA Synthetase Long Chain Family Member 1; CDKN2C, Cyclin Dependent Kinase Inhibitor 2C; ECH1, Enoyl-CoA Hydratase 1; GADD45A, Growth Arrest And DNA Damage Inducible Alpha; PIDD1, P53-Induced Death Domain Protein 1; PPOX, protoporphyrinogen oxidase; UBC, ubiquitin gene
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BMC Neuroscience

ISSN: 1471-2202

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