Fig. 3

CSDS promoted chronicity of postsurgical nociception in male mice. A Experimental procedure schematic; B Left plantar PWTs (Control, n = 12; Incision, n = 12; Stress, n = 16, Stress + Incision, n = 16, Two-way RM ANOVA, interaction: F_(33;572) = 53.33, P < 0.001, Time: F_(11;572) = 121.3, P < 0.001, Group: F_(3;572) = 80.17, P < 0.001).; C. Right plantar PWTs (Control, n = 12; Incision, n = 12; Stress, n = 16, Stress + Incision, n = 16, Two-way RM ANOVA, interaction: F_(33;572) =  = 1.248, P > 0.05, Time: F_(11;572) = 0.7852, P > 0.05, Group: F_(3;572) = 0.0902, P > 0.05). Data are represented as mean ± SEM, Data are represented as mean ± SEM, compared with the control group, *P < 0.05, ***P < 0.001; compared with the incision group, #P < 0.05, ##P < 0.01, ###P < 0.001