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Fig. 2 | BMC Neuroscience

Fig. 2

From: Exercise combined with postbiotics treatment results in synergistic improvement of mitochondrial function in the brain of male transgenic mice for Alzheimer’s disease

Fig. 2

Effects of exercise training and postbiotic treatment on APP levels (A) mouse endogenous APP/PS1 levels were determined by Western blotting with the APP-1 antibody (Abcam; ab101492) in the brain homogenates of wild type mice (Wt), control mice (APP/PS1TG), exercise trained mice (APP/PS1TG-Ex), mice with postbiotic treatment (APP/PS1TG-Pt), mice with combined training and postbiotic supplementation (APP/PS1TG-Ex-Pt) mice. C Human APPTG levels were detected with the human reactive anti-β-Amyloid antibody (Biolegend; clone 6E10). B, D Quantitative analysis of optical densities for mouse and human APP1 expression. Results show means ± SEM (n = 6). *P < 0.05 compared with APP/PS1 groups, determined by analysis of variance using Two-way ANOVA, followed by Bonferroni’s post-hoc test. Representative Western blots are shown in A and C

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BMC Neuroscience

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