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Fig. 4 | BMC Neuroscience

Fig. 4

From: Protective effect of resveratrol on mitochondrial biogenesis during hyperoxia-induced brain injury in neonatal pups

Fig. 4

(A) The fold change of mRNA expression of PGC-1α in NN, ND, NR, HN, HD, and HR groups on PN1, PN7, and PN14. (B) The fold change of mRNA expression of Sirt1 in NN, ND, NR, HN, HD, and HR groups on PN1, PN7, and PN14. (C) The fold change of mRNA expression of Nrf1 in NN, ND, NR, HN, HD, and HR groups on PN1, PN7, and PN14. (D) The fold change of mRNA expression of Nrf2 in NN, ND, NR, HN, HD, and HR groups on PN1, PN7, and PN14. (E) The fold change of mRNA expression of TFAM in NN, ND, NR, HN, HD, and HR groups on PN1, PN7, and PN14. (F) The fold change of mRNA expression of ND1 in NN, ND, NR, HN, HD, and HR groups on PN1, PN7, and PN14. (G) The fold change of mRNA expression of ND4 in NN, ND, NR, HN, HD, and HR groups on PN1, PN7, and PN14. (H) The fold change of mRNA expression of ND4/ND1 in NN, ND, NR, HN, HD, and HR groups on PN1, PN7, and PN14. *p < 0.05, **p < 0.001. NN, the nonhyperoxia group; ND, the nonhyperoxia with dimethyl sulfoxide group; NR, the nonhyperoxia with Res group; HN, the hyperoxia group; HD, the hyperoxia with dimethyl sulfoxide group; HR, the hyperoxia with Res group; PN1, postnatal day 1; PN7, postnatal day 7; PN14, postnatal day 14; PGC-1α, peroxisome proliferator-activated receptor gamma coactivator-1α; Sirt1, silencing information regulator 2-related enzyme 1; Nrf1, nuclear respiratory factor 1; Nrf2, nuclear respiratory factor2; TFAM, mitochondrial transcription factor A; ND1, NADH dehydrogenase 1; ND4, NADH dehydrogenase 4; Res, resveratrol.

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