Table 1 Demographics, clinical symptoms and global morphometric features
Normal controls (n = 36) | PD patients (n = 47) | t (χ2) | p value | |
|---|---|---|---|---|
Age (years) | 66.03 ± 8.92 | 67.21 ± 8.61 | -0.612 | 0.542 |
Sex (M/F) | 16:20 | 19:28 | 0.895 | 0.611 |
MMSE | 29.05 ± 1.32 | 28.75 ± 1.07 | 0.791 | 0.434 |
HY | - | 1.91 ± 0.47 | - | - |
Global brain morphometry | ||||
Mean CT (mm) | 3.95 ± 0.21 | 3.98 ± 0.24 | -0.751 | 0.455 |
Mean GMV (×103 mm3) | 6.49 ± 0.59 | 6.55 ± 0.68 | -0.397 | 0.692 |
Mean WMV (×103 mm3) | 3.83 ± 0.54 | 3.91 ± 0.59 | -0.591 | 0.556 |
Morphometry of left DLPFC | ||||
CT (mm) | 4.39 ± 0.42 | 4.38 ± 0.41 | 0.067 | 0.947 |
GMV (×103 mm3) | 13.39 ± 1.75 | 13.27 ± 1.99 | 0.301 | 0.764 |
WMV (×103 mm3) | 6.86 ± 1.37 | 7.05 ± 1.67 | -0.564 | 0.574 |
Pial surface area (×103 mm2) | 5.53 ± 0.69 | 5.49 ± 0.94 | 0.261 | 0.796 |
Inner surface area (×103 mm2) | 3.28 ± 0.61 | 3.27 ± 0.68 | 0.092 | 0.927 |
Gyrification index | 1.71 ± 0.22 | 1.70 ± 0.21 | 0.252 | 0.801 |