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Retraction Note: Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease

The Original Article was published on 23 February 2018

Retraction Note: BMC Neurosci19, 7 (2018).

https://doi.org/10.1186/s12868-018-0406-3

The Editor has retracted this article at the corresponding author’s request. After publication, concerns were raised regarding similarities in the presented data. Specifically:

  • In Fig. 6, the PFC 5xFAD + SLCP (2d) and CA1 5xFAD + Cur (2d) images appear highly similar;

  • Also in Fig. 6, the CA3 5xFAD + Cur (2d) and 5xFAD + SLCP (2d) appear to originate from the same sample;

  • Figure 8a GFAP 5xFAD (top) appears highly similar to Fig. 13a GFAP 5xFAD (bottom) with a brightness adjustment.

The authors checked their data and identified additional errors:

  • In Fig. 11a, the two Iba-1 5xFAD images originated from the same sample;

  • In Fig. 14a, the two Iba-1 5xFAD images originated from the same sample.

The Editor and the authors therefore no longer have confidence in the presented data.

All authors agree to this retraction.

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Correspondence to Panchanan Maiti or Gary L. Dunbar.

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The online version of the original article can be found at https://doi.org/10.1186/s12868-018-0406-3.

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Maiti, P., Paladugu, L. & Dunbar, G.L. Retraction Note: Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease. BMC Neurosci 24, 16 (2023). https://doi.org/10.1186/s12868-023-00785-5

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  • DOI: https://doi.org/10.1186/s12868-023-00785-5