Fig. 5
From: Activation of the IL-17/TRAF6/NF-κB pathway is implicated in Aβ-induced neurotoxicity
Inhibition of IL-17 attenuates Aβ42-induced neuronal damage by inactivation TRAF6/NF-κB signaling. TRAF-6 expression levels were detected by western blotting using specific antibodies, and actin was used as a loading control (A). Intensity analysis of TRAF-6 (B). Western blotting showed the expression of phospho-NF-κB p65 in the cytoplasm (C) and nucleus (E) in the hippocampus of mice. Intensity analysis of the phospho-NF-κB p65 levels in the cytoplasm (D) and nucleus (F). N = 5 for independent experiments. Data are presented as the mean ± SD. p value significance is calculated from a one-way ANOVA test, **p < 0.01 and ***p < 0.001 vs the Aβ42 group. For western blotting original images, please see Additional file 1, and Adobe Photoshop software (2021) was used to cut the parts of interest from the original images