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Fig. 3 | BMC Neuroscience

Fig. 3

From: Circ VRK1/microRNA-17/PTEN axis modulates the angiogenesis of human brain microvascular endothelial cells to affect injury induced by oxygen-glucose deprivation/reperfusion

Fig. 3

Silencing of Circ VRK1 induces angiogenesis and migration of HBMVECs. HBMVECs were infected with lentiviral vectors harboring Circ VRK1 NC or Circ VRK1 siRNA and exposed to OGD/R. A the migration of HBMVECs assessed by Transwell assay. B vessels area and total vessel length in HBMVECs assessed by tube formation assay. C VEGF mRNA expression in HBMVECs by RT-qPCR. D Representative pictures of western blotting for VEGF protein expression in HBMVECs, and all replicates are presented in the Additional file 1 (images of adequate length are not provided). Error bars represented the mean ± SD from 3 independent experiments. One-way ANOVA were used

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BMC Neuroscience

ISSN: 1471-2202

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