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Fig. 3 | BMC Neuroscience

Fig. 3

From: Positive memory increases cataplexy-like behaviors in narcolepsy mice as revealed using conditioned place preference test

Fig. 3

Negative conditioning did not change the number of cataplexy-like behavior. We used a different set of naïve orexin neuron ablated mice (four males and three females) in this study. A Two days of conditioning with an instinctively aversive odorant, 2-methyl-2-thiazoline (2MT), induced avoidance behavior, as shown by a significant decrease in preference for the 2MT-associated chamber. Meanwhile, the number of cataplexy-like behavior B–D and the duration of a single cataplexy-like episode E, F did not change by negative conditioning, except for a significant increase in the control chamber during conditioning-1 (C). Statistical significances denoted in the figure were obtained by 2-way ANOVA in (A) and by repeated design one-way ANOVA followed by Sidak's multiple comparison test, if appropriate, in (B–F)

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BMC Neuroscience

ISSN: 1471-2202

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