Fig. 2
From: Cytokine expression profiles in white blood cells of patients with small fiber neuropathy
ROC-curve analysis of cytokine gene expression levels in WBC of SFN patients compared to controls. The ROC-curves show the total AUC for IL-2, IL-8, and TNF separately (a), after combination of two out of three cytokines (b), and after merging IL-2, IL-8, and TNF together (c). AUC was highest for IL-8 (AUC = 0.69) when comparing AUC results for each cytokine separately (a). After merging, combing IL-2 with IL-8 or TNF reached the highest values (AUC = 0.78, each). Combination of three cytokines resulted in an AUC of 0.81. Numbers of samples investigated: SFN patients = 52; controls = 21. AUC area under the curve, IL− interleukin, ROC receiver operating characteristic, TNF tumor necrosis factor-alpha