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Fig. 1 | BMC Neuroscience

Fig. 1

From: Albumin alleviated esketamine-induced neuronal apoptosis of rat retina through downregulation of Zn2+-dependent matrix metalloproteinase 9 during the early development

Fig. 1

Increase of neuronal apoptosis and MMP9 expression/activity in retinal GCL after exposure to Esketamine for 5 h. A, B and C Representative images show active caspase 3 (Cas-3), MMP9 and MMP9 activity in situ zymography staining respectively in retinal GCL (area between two white dash lines) with and without esketamine exposure. Scale bar, 100 μm. (D) Bar graphs show the cells expressing cas-3 in GCL after esketamine exposure (n = 4 retinas per group). E and F The summary graph shows the fluorescence intensity of MMP9 expression (n = 4 retinas per group, E) and enzyme activity (n = 4 retinas per group, F) in GCL

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