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Fig. 5 | BMC Neuroscience

Fig. 5

From: Involvement of kynurenine pathway between inflammation and glutamate in the underlying etiopathology of CUMS-induced depression mouse model

Fig. 5

The changes in KP and its metabolites under the stress. A–D The level of KYN/TRP (A), KYN (B), QA (C) and GLU (D) in the brain were measured via HPLC. E–I The results of KYN/TRP (E), TRP (F), QA (G), KYNA/QA (H), KYNA (I) and GLU (J) in the serum. Data are expressed as the mean ± SEM. ** p < 0.01, ****p < 0.0001 vs. Control group; #p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001 vs model

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BMC Neuroscience

ISSN: 1471-2202

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