Fig. 2
From: Sirt1 protects against hippocampal atrophy and its induced cognitive impairment in middle-aged mice
Volume analysis of hippocampus and its subregions based on 3T MR brain structural imaging. A Illustrative schemes for hippocampal segmentation based on Turone Mouse Brain Atlas and Template (TMBTA). B–G Statistical analysis of (B) total intracranial volume (TIV), (C) the volume of hippocampal formation region, (D) total hippocampal volume, and the volumes of hippocampal subregions including (E) dentate gyrus region, (F) CA1 region, (G) CA2 region, and (H) CA3 region. n = 9. *p < 0.05, and **p < 0.01 represent comparison between the control group and the shSirt1 group