Analysis of risk factors and preventive strategies for intracranial infection after neuroendoscopic transnasal pituitary adenoma resection

Table 4 Univariate analysis of patients with intracranial infection after NTPAR

	Influencing factors	Infected group (n = 32)	Noninfected group (n = 355)	Infection rate (%)	X² value	P value
Sex	Male	12	170	6.59	1.271	0.274
Sex	Female	20	185	9.76
Age (years)	> 45	19	140	11.95	4.821	0.028
Age (years)	≤ 45	13	215	5.70
BMI (kg/m²)	> 24.9	8	102	7.27	0.201	0.654
	≤ 24.9	24	253	8.66
History of hypertension	Yes	11	87	11.11	1.512	0.219
History of hypertension	No	21	268	7.23
History of diabetes	Yes	8	56	12.5	1.810	0.179
History of diabetes	No	24	299	7.43
ASA score	> 2	8	117	6.40	0.794	0.737
ASA score	≤ 2	24	238	9.16
Tumour size (cm)	> 1	29	266	9.83	3.990	0.046
Tumour size (cm)	≤ 1	3	89	3.26
Operation time (min)	> 240	16	85	15.84	10.333	0.001
Operation time (min)	≤ 240	16	270	5.59
Bleeding volume (ml)	> 400	9	39	18.75	7.936	0.005
Bleeding volume (ml)	≤ 400	23	316	6.78
Kelly Grade	> 2	6	22	21.43	6.890	0.009
Kelly Grade	≤ 2	26	333	7.24
Postoperative CSF leakage	Yes	10	37	21.27	11.934	0.001
Postoperative CSF leakage	No	22	318	6.47
Sinusitis	Yes	9	58	13.43	2.849	0.091
Sinusitis	No	23	297	7.19
Antibacterial drug use during perioperative period	Yes	26	327	7.37	4.322	0.038
Antibacterial drug use during perioperative period	No	6	28	17.65
Lumbar cistern drainage	Yes	5	18	21.74	5.85	0.016
Lumbar cistern drainage	No	27	337	7.42
Blood transfusion	Yes	5	19	20.83	5.325	0.021
Blood transfusion	No	27	336	7.44

ISSN: 1471-2202