Table 3 Clinical data of 387 patients with pituitary tumours

Sex (male, %)

47.89%

37.50%

0.274^a

Age (x ± s, years)

44.84  ±  13.28

48.81 v 14.81

0.151^b

BMI (x ± s, kg/m²)

22.16 ± 2.61

22.26 ± 2.27

0.815^b

History of hypertension (%)

34.37%

24.51%

0.219^a

History of diabetes (%)

15.78%

25%

0.179^a

ASA score (x ± s)

1.88 ± 0.88

1.93 ± 0.76

0.697^b

Tumour size (x ± s, cm)

2.02 ± 0.99

2.43 ± 1.02

0.035^b

Small adenoma (case)

70

2

Large adenoma (case)

270

26

Giant adenoma (case)

15

4

Operation time (x ± s, minutes)

198.51 ± 81.68

245.5 ± 86.57

0.005^b

Bleeding volume (x ± s, ml)

267.79 ± 111.55

397.81 ± 141.96

0.000^b

Kelly Grade of intraoperative CSF leakage (x ± s, Grade)

0.96 ± 0.84

1.50 ± 1.05

0.007^b

0 (cases)

109

6

1 (case)

175

11

2 (cases)

48

8

3 (cases)

23

7

Postoperative CSF leakage (cases, %)

10.42%

28.12%

0.001^a

Sinusitis (cases, %)

16.34%

31.25%

0.091^a

Use of antibacterial drugs during perioperative period (%)

92.11%

81.25%

0.038^a

Drainage of lumbar cistern (%)

5.07%

15.62%

0.016^a

Blood transfusion (%)

5.35%

15.62%

0.021^a