Fig. 1
Increased Aβ42 in PDD and decreased p-TauS199/202 levels in DLB. Multivariate analysis of post-mortem samples from the TC and CP regions of controls and individuals with PDD and DLB. a Protein levels of Aβ42 in the TC by ELISA assay; 100 µg of each protein sample was used per ELISA reaction. N = 5. b p-APPT668 and APP protein levels were measured in the TC samples by western blot. Twenty micrograms of protein were used per well for SDS-PAGE. Protein values are normalized to β-actin levels and control samples. Blots were cropped from different gels. Representative western blot images were shown. All blot images with significant changes were included in the Additional file 1: Fig. S1. c Statistical results of relative p-APPT668 protein levels normalized to APP levels in the TC. d p-TauS199/202 protein levels were measured in CP by western blot. Blots were cropped from different gels. Representative western blot images were shown. Protein values are normalized to β-actin levels and control samples. e Statistical results of relative p-TauS199/202 levels in the CP samples. Data are presented as the mean ± SEM. Kruskal–Wallis test was used to measure the differences between Control, PDD, and DLB samples. *p < 0.05, **p < 0.01, ***p < 0.001. Sample numbers, Control = 9, PDD = 10, and DLB = 9