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Table 5 The multivariable linear regression analysis between impulsivity and biomarkers

From: Fibroblast growth factor 21 associating with serotonin and dopamine in the cerebrospinal fluid predicts impulsivity in healthy subjects

Variables BIS total scores
Model 1 β coefficient (95% CI) Model 2 β coefficient (95% CI) Model 3 β coefficient (95% CI)
CSF serotonin (pg/ml) −0.034 (−0.059; −0.009)** −0.038 (−0.063; −0.013)** −0.037 (−0.063; −0.011)**
CSF Dopamine (pg/ml) −0.105 (−0.184; −0.026)** −0.122 (−0.202; −0.042)** −0.116 (−0.200; −0.031)**
  1. Model 1: unadjusted
  2. Model 2: adjusted for age and education years
  3. Model 3: adjusted for age, education years, BMI, and pain levels
  4. **: p < 0.01; FGF, fibroblast growth factor; BIS, Barratt Impulsiveness Scale; CI, confidence interval