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Table 4 Chronic effects of OSE and CSE on blood levels of BDNFP, BDNFS, IGF-1 and IL-6

From: Comparison of the effects of open vs. closed skill exercise on the acute and chronic BDNF, IGF-1 and IL-6 response in older healthy adults

Variable

cOSE

cCSE

Pre

Post

Change

Pre

Post

Change

BDNFP (pg/ml)

1695.0 (837.5)

1810.0 (760.0)

+ 35.0 (1392.5)

1620.0 (810.0)

1850.0 (2168.0)

+ 63.0 (1739.0)

BDNFS (pg/ml)

25,200.0 (4800.0)

27,400.0* (7650.0)

+ 2450.0 (4625.0)

30,700.0 (6450.0)

32,400.0 (14,050.0)

+ 3600.0 (11,500.0)

IGF-1 (ng/ml)

209.5 (96.8)

158.5* (90.3)

− 34.5 (34.25)

180.0 (81.0)

146.0# (63.0)

− 21.0 (86.5)

IL-6 (ng/L)

1.6 (1.6)

5.4* (2.4)

+ 3.8 (2.8)

1.5 (4.7)

5.9 (1.4)

+ 4.0 (5.4)

  1. Median values (interquartile range) of BDNFP, BDNFS, serum IGF-1, and serum IL-6 at pre-test and post-test
  2. BDNF brain-derived neurotrophic factor; IGF-1 insulin-like growth factor 1; IL-6 interleukine-6
  3. Asterisk indicates a significant difference between pre-test and post-test (*0.050 >  p  ≥ 0.001)
  4. Number sign indicates a tendency for difference between pre-test and post-test (#0.100 >  p  ≥ 0.050)