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Table 2 Characteristics of morphometric indicators of the microcirculatory bed of the brain in the investigated groups of rats (M + m)

From: The functional indexes of RBCs and microcirculation in the traumatic brain injury with the action of 2-ethil-6-methil-3-hydroxypiridin succinate

Value Intact rats Group Period after TBI (day)
1 3 7 12
Diameter of the capillary, µm2 5.5
5 ± 0.06
Control 3.25 ± 0.05* 3.95 ± 0.06* 5.21 ± 0.05* 5.94 ± 0.03*
Experiment 3.53 ± 0.04* 3.49 ± 0.05* 4.75 ± 0.03* 5.19 ± 0.04*
Area of the capillary, µm2 41.9
 ± 5.31
Control 114.86 ± 12.32* 154.64 ± 10.41* 129.69 ± 9.87* 109.06 ± 34.51*
Experiment 120.62 ± 9.85* 124.28 ± 8.63* 98,.6 ± 9.45* 45.02 ± 6.21*
Area of pericapillary edema, µm2 124.2
 ± 12.83
Control 375.79 ± 27.51* 533.86 ± 34.71* 277.04 ± 28.08* 194.64 ± 24.18*
Experiment 345 ± 26.82* 262.82 ± 14.54 * 144.29 ± 11.05 117.75 ± 12.47
Area of the capillary bed, µm2 628
 ± 32.24
Control 456 ± 26.01* 854 ± 41.64* 748 ± 34* 560 ± 29*
Experiment 904.65 ± 38.32* 1 118.2 ± 35.26* 884 ± 31* 630 ± 33
Area of the venules, µm2 185
 ± 14.21
Control 335.62 ± 20.14* 356.05 ± 19.32* 293.67 ± 18.41* 254.06 ± 17.64*
Experiment 328.91 ± 21.01* 282 ± 17.64
*
22,658 ± 15.32* 205.17 ± 15.08
Area of perivascular edema of venules, µm2 124.2
 ± 12.83
Control 801.75 ± 21.51* 906.24 ± 25.68* 574.28 ± 22.56* 391.26 ± 19.42*
Experiment 774.08 ± 24.13* 504.78 ± 21.25* 308.2 ± 17.34 * 178.35 ± 14.72 *
Area of the arterioles, µm2 320
 ± 15.2
Control 458 ± 25.45* 471 ± 26.81* 421 ± 18.21* 408 ± 16.14*
Experiment 452 ± 24.62* 403 ± 21.51* 373 ± 18.93 * 306 ± 14.72 *
Area of perivascular edema of arterioles, µm2 243.2
 ± 14.72
Control 925.16 ± 25.16* 1059.75 ± 21.5* 719.91 ± 22.14* 510 ± 20.05 *
Experiment 899.48 ± 19.63* 834.19 ± 17.64* 514.78 ± 15.64* 266.22 ± 16.35
Swelling of the neuron, µm2 140.43
 ± 8.74
Control 251 ± 12.36* 264 ± 11.04* 220 ± 12,31* 206.66 ± 8,84*
Experiment 208.85 ± 9.75* 204.7 ± 10.62* 168 ± 7.84* 136.25 ± 5.64*
  1. Data are means ± SD. “*” statistically important differences regarding the intact group data, p < 0,05, “” statistically important differences of experiment from control, p < 0,05