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Table 1 The change in functional indexes of RBCs (erythrocytes) in the TBI post-traumatic period of rats in the investigated groups

From: The functional indexes of RBCs and microcirculation in the traumatic brain injury with the action of 2-ethil-6-methil-3-hydroxypiridin succinate

Value Intact rats Group Period after TBI (day)
1 3 7 12
RBC electrophoretic mobility,
μm∙cm∙V-1∙s−1
1.19
 ± 0.03
Experiment 1.02 ± 0.02* 1.07 ± 0.03* 1.08 ± 0.03* 1.11 ± 0.02 *
Control 0.78 ± 0.03* 0.85 ± 0.03
*
0.93 ± 0.03
*
1.05 ± 0.02
*
RBC aggregation, % 36.85
 ± 1.17
Experiment 87.82 ± 3.79* 49.84 ± 5.81* 44.22 ± 2.51
*
38.19 ± 1.18
Control 85.81 ± 0.74* 77.89 ± 1.35* 69.09 ± 1.13* 59.68 ± 0.75*
MDA,
nmol/ml
0.08
 ± 0.01
Experiment 0.20 ± 0.04
*
0.09 ± 0.02
*
0.08 ± 0.04
0.10 ± 0.04
Control 0.23 ± 0.02* 0.18 ± 0.04* 0.19 ± 0.03* 0.14 ± 0.02*
Catalase, units/gHb∙min 28.23
 ± 0.66
Experiment 38.63 ± 1.98* 41.59 ± 1.97* 29.79 ± 1.34 34.61 ± 1.58*
Control 20.46 ± 0.49* 17.02 ± 0.75* 16.65 ± 0.81* 17.28 ± 1.3*
ATP,
μmolPn/mL
1.78 ± 0,17 Experiment 1.27 ± 0.17* 2.17 ± 0.13 2.72 ± 0.21* 2.85 ± 0.39*
Control 1,49 ± 0.17 2,28 ± 0.19* 2.56 ± 0.13* 2.37 ± 0.19*
2.3-BPG,
μmolPn/mL
2.99 ± 0.25 Experiment 5.16 ± 0,42* 6.68 ± 0,23* 5.68 ± 0,26* 4.26 ± 0,28*
Control 5.22 ± 0.57* 5.12 ± 0,25* 4.01 ± 0,34* 3.79 ± 0,32
  1. Data are means ± SD. “*” statistically important differences regarding the intact group data, p ≤ 0.05, “” statistically important differences of experiment from control, p ≤ 0.05