Fig. 4

Measures for hippocampal ictal and interictal events of thick slices. A Thick hippocampal slices obtained from young mice (21–28 days-old). Proportion of slices with or without detected ictal discharges or interictal spikes was estimated. The “ictal” category refers to slices that displayed discharges spontaneously or following HFS, irrespective of associated interictal spikes; the “interictal” refers to slices that expressed interictal spikes spontaneously or following HFS, but no spontaneous or HFS-induced ictal discharges; the “no” denotes slices that did not exhibit spontaneous nor HFS-induced epileptiform field potentials. B Interevent intervals of interictal spikes measured from individual thick slices. C, D Interevent intervals and durations of ictal discharges measured from individual slices with ≥ 5 recurrent discharge events. Box plots presented in B–D, and interquartile range abbreviated as IQR