Neurologic effects of short-term treatment with a soluble epoxide hydrolase inhibitor after cardiac arrest in pediatric swine

Table 3 Ischemic neurons per mm² in the 4 experimental groups at 4 d recovery

Anatomic area	Sham + Veh (n = 8)	Sham + TPPU (n = 9)	CA + Veh (n = 9)	CA + TPPU (n = 8)	p
Anterior putamen	3 [1, 7]	1 [0, 3]	43 [37, 93]^a	68 [24, 107]^b	< 0.001
Posterior putamen	1 [0, 5]	2 [0, 5]	43 [8, 80]^c	20 [3, 65]	0.003
Motor cortex	1 [1, 2]	4 [1, 7]	8 [4, 14]	6 [3, 13]	0.053

Data are presented as median and interquartile range. Data were analyzed by Kruskal–Wallis test with post hoc Dunn’s multiple comparisons test
CA, cardiac arrest; Veh, vehicle
^ap = 0.026 vs Sham + Veh and p < 0.001 vs Sham + TPPU
^bp = 0.016 vs Sham + Veh and p < 0.001 vs Sham + TPPU
^cp = 0.013 vs Sham + Veh and p = 0.028 vs Sham + TPPU

ISSN: 1471-2202