Fig. 1

In vitro mouse NMJ EPPs with model reconstruction (blue). A Control: number of release sites N=100, release probability p=0.4, quantal size q=0.13mV, background noise σ=0.2mV, depression time constant τ_d=95ms, refilling time constant τ_f=50ms, desensitization τ_des= 30ms. B Curare administration: N=100, p=0.5, q=0.05mV, σ=0.1mV, τ_d=45ms, τ_f=50ms, τ_des=30ms. C Cartoon of a synaptic junction. Comparison of estimation of parameters with rat NMJ can be found in [3]