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Table 5 Brain DML (p < 0.0001); PD cases with OGC pesticide exposure 4+ vs 0–2 detectable levels

From: Genome-wide epigenetic analyses in Japanese immigrant plantation workers with Parkinson’s disease and exposure to organochlorines reveal possible involvement of glial genes and pathways involved in neurotoxicity

PROBESET ID

CHR

CpG location

Gene name

p-value (Code 2 vs 0)

Methylationa

cg18397450

14

Body; Body

PACS2

1.18E−06

+

cg18912855

14

Body

PACS2

1.60E−05

+

cg02101742

13

Body

TFDP1

1.68E−05

cg09677945

13

5′UTR; 1stExon

DNAJC15

1.73E−05

+

cg15988970

13

5′UTR; 1stExon

DNAJC15

2.82E−05

+

cg25499461

19

TSS200

IRF2BP1

5.28E−05

+

cg15909600

22

TSS1500

MAPK8IP2

6.08E−05

+

cg06534988

5

Intergenic

 

8.05E−05

  1. a Hyper (+) or Hypo (−) methylation